Báo cáo khoa học: The catalytic role of the distal site aspa

Tài liệu Báo cáo khoa học: A possible role of mitochondria in the apoptotic-like programmed nuclear death of Tetrahymena thermophila Takashi Kobayashi and Hiroshi Endoh docx

... which appear to be involved in the ﬁnal resorption of the parental macronucleus during PND in T. thermophila, and suggested the involvement of mitochondria in this process [19]. In mammalian apop- tosis, ... becomes acidic in the ﬁnal step of PND [22,23]. DePsipher staining of the macronucleus appeared initially during the stage of autophagosome formation, and...

Ngày tải lên : 20/02/2014, 03:20

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Báo cáo khoa học: Zinc-binding property of the major yolk protein in the sea urchin ) implications of its role as a zinc transporter for gametogenesis ppt

... is incorporated into the nutritive phagocytes, some of the CFMYP forming homotetramers is pro- cessed to EGMYP, with loss of zinc-binding site( s); the remainder retains zinc. When CFMYP is incorporated ... determined by ICP-AES. To investigate the accumulation of zinc in the gonads during gametogenesis, increases in the size of the gonads during this period were...

Ngày tải lên : 16/03/2014, 05:20

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Tài liệu Báo cáo khoa học: An autoinhibitory effect of the homothorax domain of Meis2 ppt

... proteins bind their cognate DNA-binding site, they generally bind to other DNA-binding cofactors [10–12]. Meis2 is a member of the TALE superfamily of HD proteins, which are characterized by the ... by the interaction of Pbx1 with the Hth domain of Meis2. Target- ing of the Hth domain to DNA suggests that it is not a portable trans- acting repression domain. However, t...

Ngày tải lên : 16/02/2014, 15:20

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Tài liệu Báo cáo khoa học: Investigation and prediction of the severity of p53 mutants using parameters from structural calculations pptx

... residue 283 is involved in DNA binding. However, residues 272 and 276 are close to DNA binding. The other four residues are further away, but at the same side of the protein, indicating a possible ... procedures. In the local minimiza- tion, the sum of the energy terms was minimized locally in the direction in which the total energy gradient was the steep- est....

Ngày tải lên : 18/02/2014, 11:20

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Tài liệu Báo cáo khoa học: Substrate speciﬁcity of the pseudouridine synthase RluD in Escherichia coli doc

... isomerizes uridine in vivo only at positions 1911, 1915, and 1917, regardless of the presence of uridine at other positions in the loop of helix 69 of 23S rRNA variants; (b) substitution of one U ... no effect on the conversion of others (i.e. formation of pseudouridines at positions 1911, 1915, and 1917 are independent of each other); (c) A1916 is the only posit...

Ngày tải lên : 18/02/2014, 16:20

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Tài liệu Báo cáo khoa học: Receptor binding characteristics of the endocrine disruptor bisphenol A for the human nuclear estrogen-related receptor c pptx

... environments of BPA in the ligand-binding pocket of the ERRc. The proximity of each amino acid residue (within a distance of 5 A ˚ ) to BPA is shown in the boxes depicting the a -heli- ces. The portrait ... activity of the latter and to reverse the deactivating inverse agonist activity of 4-hydroxytamoxifen. However, the intrinsic binding mode of bisphenol...

Ngày tải lên : 18/02/2014, 16:20

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Tài liệu Báo cáo khoa học: N-terminal extension of the yeast IA3 aspartic proteinase inhibitor relaxes the strict intrinsic selectivity ppt

... conserved in the sequence of saccharopepsin, the validity of this inter- pretation was examined by determination of inhibition constants for the interaction of the N-terminally exten- ded inhibitors ... ‘remote’ attachment of residues 35–81 from its own C-terminal segment, cause only minor perturbation of the inhibi- tory potency intrinsic to the N-terminal segment....

Ngày tải lên : 19/02/2014, 00:20

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Tài liệu Báo cáo khoa học: Salt-induced formation of the A-state of ferricytochrome c – effect of the anion charge on protein structure docx

... charges bind to spe- cific sites of horse cytochrome c [19,27]. To determine whether divalent anions bind to the same sites, we introduced some mutations within the site- containing regions of the macromolecule, ... with the aim of defining the role played by single residues in modulating protein affinity for divalent anions. On the basis of earlier work [19,27], the...

Ngày tải lên : 19/02/2014, 05:20

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Tài liệu Báo cáo khoa học: Co-operative effect of the isoforms of type III antifreeze protein expressed in Notched-ﬁn eelpout, Zoarces elongatus Kner ppt

... cloning and sequence alignment of nfeAFPs The complete amino acid sequences of the 13 isoforms of nfeAFP were determined based on the cDNA A B Fig. 2. (A) HPLC puriﬁcation of the isoforms of type ... m M nfeAFP13 in the absence of dithiothreitol. The protein standards (MW) are indicated on the left. The mono- mer of nfeAFP13 is the dominant species irrespecti...

Ngày tải lên : 19/02/2014, 16:20

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Tài liệu Báo cáo khoa học: A kinetic model of the branch-point between the methionine and threonine biosynthesis pathways in Arabidopsis thaliana doc

... first, the activating interaction of AdoMet with TS may attenuate the changes in the flux of threonine due to a modification of the level of AdoMet. Indeed, upon an increase in the level of AdoMet, ... branch-point kinetics in detail and to obtain insights into the kinetic controls of methionine and threonine synthesis in plants. The branch-point between the m...

Ngày tải lên : 20/02/2014, 02:21

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Báo cáo khoa học: The catalytic role of the distal site asparagine-histidine couple in catalase-peroxidases potx

Tài liệu Báo cáo khoa học: A possible role of mitochondria in the apoptotic-like programmed nuclear death of Tetrahymena thermophila Takashi Kobayashi and Hiroshi Endoh docx

Báo cáo khoa học: Zinc-binding property of the major yolk protein in the sea urchin ) implications of its role as a zinc transporter for gametogenesis ppt