Báo cáo khoa học: Upstream and intronic regulatory sequences interact in the activation of the glutamine synthetase promoter pot
Báo cáo khoa học: Upstream and intronic regulatory sequences interact in the activation of the glutamine synthetase promoter pot
... Upstream and intronic regulatory sequences interact in the
activation of the glutamine synthetase promoter
Rocio M. Garcia de Veas Lovillo, Jan M. Ruijter, Wil T. Labruye
`
re, Theodorus ... interactions
of upstream and intronic regulatory elements do indeed
determine the degree of activation of the GS promoter and
that these interactions di...
Báo cáo khoa học: "Computing and Evaluating Syntactic Complexity Features for Automated Scoring of Spontaneous Non-Native Speech" pot
... version of the test set contains ASR
hypotheses instead of human transcriptions. The
word error rate (WER
4
4
Word error rate (WER) is the ratio of errors from a string
between the ASR hypothesis ...
number of syntactic complexity features in the ag-
gregated file. Therefore we joined files from the
same speaker to one file for the training set and the
fiv...
Báo cáo khoa học: UDP-galactose 4-epimerase from Kluyveromyces fragilis – catalytic sites of the homodimeric enzyme are functional and regulated docx
... revived interest in
exploring the regulatory behavior of this enzyme. To
avoid misinterpretation of the results, the composition
and stoichiometry of the bound cofactor(s) and the
stability of the ... been used in
the context of binding of the inhibitor 5¢-UMP to epimerase.
The terms native, inhibitor-free and monomeric epimerase
have been used in...
Báo cáo khoa học: "Cohesion and Collocation: Using Context Vectors in Text Segmentation" pptx
... move over the input text, and at
pre-determined intervals (every 10 words), the vec-
tors associated with the words in each window are
added up, and the cosine between the resulting win-
dow ... again be compared against each other and
word vectors. If the word vectors in two adjacent
portions of text are added up, then the cosine be-
tween the two resulting...
Báo cáo khoa học: TioS T-TE – a prototypical thioesterase responsible for cyclodimerization of the quinoline- and quinoxaline-type class of chromodepsipeptides potx
... subdivided into two main
groups (i.e. the quinoxalines and the quinolines),
depending on the chromophore moiety bound to the
N-termini of each oligopeptide chain. Prominent mem-
bers of the quinoxaline-group ... assembly line [11].
The resulting structure can be either branched-cyclic,
as in the case of the last-line antibiotic daptomycin, or
closed, as in the ca...
Báo cáo khoa học: FLIP and MAPK play crucial roles in the MLN51-mediated hyperproliferation of fibroblast-like synoviocytes in the pathogenesis of rheumatoid arthritis pdf
... of
sustained in ammation and angiogenesis in arthritic
joints [2–4]. Several cytokines and RA factors existing
in the RA environment stimulate the overgrowth of
FLSs, leading to the aggravation of ... localization, and
regulation of the stress-activated protein kinases, extra-
cellular signal-regulated kinase, c-JUN N-terminal
kinase, and p38 mitogen-activated pro...
Báo cáo khoa học: ERK and cell death: ERK1⁄2 in neuronal death Srinivasa Subramaniam1 and Klaus Unsicker2 pptx
... U0126 (which inhibits
mitogen-activated protein kinase/ERK kinase (MEK),
an upstream activator of ERK1⁄ 2). Both of these
inhibitors also inhibit ERK5 activation [10]. Therefore,
it remains to be ... signal-regulated
kinases 1 and 2 (ERK1 ⁄ 2), the c-JunNH
2
-terminal kin-
ases (JNK) and the p38 kinases. There is a widely
accepted perception that JNK⁄ SAPK (stress-activated
pr...
Báo cáo khoa học: ERK and cell death: cadmium toxicity, sustained ERK activation and cell death pot
... activation of
Raf in this system results in sustained activations of
MEK and ERK. These activations in turn result in
the onset of apoptosis via the death receptor path-
way, but are independent of the ... cadmium
poisoning [33,38].
In conclusion, these data strongly suggest that
ROS production following cadmium poisoning results
in both the activation of...
Báo cáo khoa học: Cholesterol and its anionic derivatives inhibit 5-lipoxygenase activation in polymorphonuclear leukocytes and MonoMac6 cells pot
... propose that inhibition
of LT synthesis by CS contributes to the suppressive
effect of CS in gastric in ammation.
Regarding the role of CS in inflammation and athero-
genesis, other activities of CS ... given in the pres-
ence (hatched columns) and in the absence (empty columns) of
20 l
M AA in the medium.
Fig. 5. The CS effect on LT synthesis is inhibited...
Báo cáo khoa học: TRAF6 and C-SRC induce synergistic AP-1 activation via PI3-kinase–AKT–JNK pathway pptx
... (TRAF6)
[5–9]. Kinase, TAK1 and two interacting proteins, TAB1
and TAB2, are also implicated in IL-1 signaling [10,11], in
which TAK1 activates the kinase, NIK, directly, leading to
the activation of NF-jB. ... signaling also lead
to the activation of c-Jun N-terminal kinase (JNK) and
other mitogen-activated protein kinase [6,9,12–14], that
results in the phosphory...
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