Báo cáo khoa học: Expression, localization and potential physiological significance of alcohol dehydrogenase in the gastrointestinal tract pdf

... demonstrate that ADH1 and ADH4 coexist throughout the gastrointestinal tract and provide new data to understand the physiological role of ADH classes in the gastrointestinal tract and the etiopathogeny related ... products of lipid peroxidation [12,13]. ADH4, located in the upper part of the gastrointestinal tract and the luminal part of the m...

Ngày tải lên: 23/03/2014, 17:22

... the FMN domain, converting some of the enzyme to the active form. The  3-fold increase in activity may arise from the binding of the FMN domain to hMS facilitating binding of AdoMet and ⁄ or methyl ... domain with the hMS AD. Fig. S2. Comparison of the electrostatic potentials of the surface of the CPR FMN domain and of a model of the FMN domain o...

Ngày tải lên: 18/02/2014, 08:20

... alveolar macrophages. The synthetic peptides also inhibited the secretion of the CXC chemokine interleukin-8 (GRO ⁄ CINC-1) in response to lipopolysac- charide. The presence of H4-v.1 and histogranin mRNAs in tissues ... end, lack- ing the 5¢UTR and the first ATG initiation codon present in bovine H4-v.1. On the other hand, a tblastn search of NCBI for histone H4...

Ngày tải lên: 16/03/2014, 13:20

... understood. In the present study, we investigated whether ligand binding affects the turnover and ubiquitination of the PPARb subtype (also known as PPARd). Our data show that the ubiquitination and ... exam- ple, in protecting the cell against the overexpression of PPARb in pathophysiological conditions. Further- more, our findings indicate that the experimental da...

Ngày tải lên: 30/03/2014, 03:20

... schematically depicted and the binding epitope for the anti-EpoR immunoglobulin is indicated. The calibrator, GST-EpoR, consists of the protein domain containing the antibody-binding site fused to ... use the erythropoietin receptor (EpoR)-induced activation of ERK1 in the hematopoietic suspension cell line, BaF3-hemaglutinin-tagged (HA)-EpoR, and the interleukin-6 (...

Ngày tải lên: 19/02/2014, 07:20

... that the inference of the user’s overall intention via DA detection is an important task in SDS. Figure 1 depicts the training and test phases of the SLU module and the DM module in our system. The ... (DAs), counting the occurrences the DRs in DA, and intro- ducing an entropy-based weighting scheme (Belle- garda, 2000). This matrix is pivotal in the comput...

Ngày tải lên: 20/02/2014, 05:20

... 18.7 A ˚ on binding of cAMP to the anti-cAMP-binding sites of the protein. The distance between the sulfur atom of Cys178 and the C9–C10 bond of the indole ring of Trp85, derived from the crystal ... absence of cAMP in apo-CRP, some b strands of the N-terminal domain of the protein may collapse into the cAMP-binding pocket, causing reorientation of t...

Ngày tải lên: 20/02/2014, 23:20

... contents in the shifted complexes 1 and 2 and in the unbound labeled O1O2 DNA were determined by scanning the intensities of all the bands shown in the autoradiogram of the gel shift assay (I) and ... interact with the CI. The data, however, confirm that 15 bp O1 and O2 DNAs are involved in the binding of CI. The intensities of some top ()53G) and...

Ngày tải lên: 07/03/2014, 00:20

... able to discover 72.8% of the elements of the Top 100 list. However, increasing thevalues of q and B also increases search time. With a beam (B) of 100 and the number of random permutations equal to ... after applying the random permutation function π), we calcu- late the hamming distance of every vector with 2 The jumbling is performed by a mapping of the bit...

Ngày tải lên: 08/03/2014, 04:22

... tags, the lexical forms and the in- flection forms of the two morphemes pre- ceding µ; 2. the POS tags and the lexical forms of the two morphemes following µ; 3. the lexical form and the in ection ... not. During the test phase, first the ranking of the candidate classes for a given example is as- signed by the stochastic model as in the training. Then...

Ngày tải lên: 17/03/2014, 08:20