Báo cáo khoa học: Etoposide upregulates Bax-enhancing tumour necrosis factor-related apoptosis inducing ligand-mediated apoptosis in the human hepatocellular carcinoma cell line QGY-7703 pdf

... 270) 2731 Etoposide upregulates Bax-enhancing tumour necrosis factor-related apoptosis inducing ligand-mediated apoptosis in the human hepatocellular carcinoma cell line QGY-7703 Lin Miao, Peng ... TRAIL on the liver carcinoma cells QGY-7703 To investigate the apoptotic function of TRAIL containing the extracellular domain (amino acids 114–281) of...

Ngày tải lên: 23/03/2014, 17:22

... the clinical pharmacist, comprising 1,286 in the C-U and 1,224 in the PB-U. In the C-U, 44 MPEs occurred versus 331 in the PB-U (3.4% versus 27.0%, P < 0.001). Overall, the ICIS resulted in ... medication ordering. These results are shown in Table 3. In the C-U, the minor MPEs were mainly wrong pharmaceutical form errors and infusion rate errors. The interce...

Ngày tải lên: 25/10/2012, 10:39

... footnote) in the reaction mixture may reduce a proportion of the FMN domain, converting some of the enzyme to the active form. The  3-fold increase in activity may arise from the binding of the FMN ... mL. The reactions were initiated by the addition of homo- cysteine following 5 min of incubation at 37 °C of the enzyme with all other components. Following 10 min of i...

Ngày tải lên: 18/02/2014, 08:20

... in the neuroendocrine organ, a puzzling question remains unanswered: how are these peptides distributed in the different cells of the X organ–sinus gland system? In other words, what is the cellular ... Orconectes limosus, showing that l-isomer of CHH is always present in the different parts of the d-CHH cells, in decreasing amounts from the cell body to the axon t...

Ngày tải lên: 18/02/2014, 11:20

... the mechanism in which heparin binding to the basic cluster in APC is responsible for the observed inhibitory activity. A direct effect of heparin on APC can also explain the stimulation of the ... the NMR/modeled structure of heparin (file 1hpn [35]). Amino acids known to be part of the heparin-binding site in these three crystallized protein–heparin complexes were given a...

Ngày tải lên: 19/02/2014, 13:20

... of proteins involved in retinoid-related metabolism (retinoic acid receptors, cellular binding proteins and oxidizing enzymes) have been mapped within the adult dopamine system [35]. In the adult ... data indicate that adult brain tissue, in particularly the striatum, can oxidize retinol to retinal, providing the first step on the way to retinoic acid [31]. The brain must thu...

Ngày tải lên: 21/02/2014, 00:20

... mutants, these findings may indicate that CagD is released into the supernatant during host cell infec- tion by an unknown independent mechanism and then binds to the host cell surface or is incorporated ... other bacteria. The other cagPAI components repre- sent almost unique proteins in this scenario. The majority of the T4SS include approximately fifteen components, taking in...

Ngày tải lên: 06/03/2014, 00:21

... interested in investigating the effect of miR-143 on the cellular response to 5-FU. 5-FU is a well-known apoptosis- inducing drug; indeed, it was shown previously that 5-FU induces apoptosis in HCT116 cells ... hampers miR-143 pro- cessing in a transcription-independent manner. These results are once again in agreement with the results obtained in SW480 cells. In these...

Ngày tải lên: 07/03/2014, 00:20

... However, the C-terminal amino acid sequences, such as ERPGR in the human precursor or QRPGR in the bovine precursor are similar to the sequence of lamprey PQRFa-RP-1. The precursors of other vertebrates ... of the only two extant representative species of the oldest lineage of vertebrates, the Agna- tha, which diverged from the main line of vertebrate evolution  450...

Ngày tải lên: 07/03/2014, 12:20

... kinases that are thought to act upstream of the mitogen-activated protein kinas- es (see the accompanying minireview [11] on the bio- chemical interactions of the CCM proteins). Furthering the ... again hinting that the endothelial cell is the cell type that most needs the function of the CCM proteins [25]. Later work also showed that loss of heg or vtn via morpholino kn...

Ngày tải lên: 15/03/2014, 10:20