Báo cáo khoa học: Chick embryo anchored alkaline phosphatase and mineralization process in vitro Influence of Ca 2+ and nature of substrates doc

... Chick embryo anchored alkaline phosphatase and mineralization process in vitro In uence of Ca 2+ and nature of substrates Eva Hamade, Ge´rard Azzar, Jacqueline Radisson, Rene´Buchet and ... France.ResultsEvidence of different steps in the GPI-bALP mediated mineralization: effects of Ca 2+ concentrationTo assess the role of Ca 2+ in initiating the mineralization process, we modelled the biological process ... substrates aﬀecting the nucleation process or producing inhibitors of the mineralization. Keywords: anchored bone alkaline phosphatase; minerali-zation; Ca 2+ ; hydroxyapatite. Alkaline phosphatase...

Tài liệu Báo cáo khoa học: Mitogen-activated protein kinase phosphatase-1 modulated JNK activation is critical for apoptosis induced by inhibitor of epidermal growth factor receptor-tyrosine kinase pdf

... 91–118.19 Hibi M, Lin A, Smeal T, Minden A & Karin M (1993)Identiﬁcation of an oncoprotein- and UV-responsiveprotein kinase that binds and potentiates the c-Junactivation domain. Genes Dev ... cell line PC-9. To investigate the signaling routeby which AG1478 induced apoptosis, we examined the activation of c-JunN-terminal kinase (JNK) and mitogen-activated protein kinase p38 in AG1478-treated ... thatthe inhibition of ERK1 ⁄ 2 MAPK and ⁄ or PtdIns3K ⁄Akt growth ⁄ survival signaling cascades leads to apop-tosis of cancer cells. However, there are no studiesaddressing the role of JNK in apoptosis...

BÀI BÁO CÁO KHOA HỌC TẠI BẮC KINH ATCM 2009 THE SCIENTIFIC REPORT IN BEIJING - CHINA

... mathematical problems ” Therefore, I have built math-calculator subject and technology in mathematicsWE CAN USE SCIENTIFIC CALCULATORS :1.VIETNAM CALCULATOR VN- 570RS3.CASIO FX-570MS4.CASIO ... : Find the eighteenth digit after of the decimal point of We use calculators :VietnamCalculator Vn-570RS,Vn-500RS,CASIO fx – 570MS,fx – 570ES , fx – 991ES,fx-82ES,HP- 10S,HP-300S 337INTRODUCTION6.Calculate ... :we continue to find the end five digits of P and we guess that the digit 8 can have rounded, so we only calculate7 77 777 7777 77777 13+ + + + ×272367=> The end five numerals of P are...

Tài liệu Báo cáo khoa học: Accessibility changes within diphtheria toxin T domain when in the functional molten globule state, as determined using hydrogen⁄deuterium exchange measurements pdf

... into two fragments: the A chaincorresponding to the catalytic domain (C domain); and the B chain corresponding to the translocationdomain (T domain) and the receptor-binding domain.The C and ... identify the core of the pro-tein in the N- and MG states, the regions of moderate and high accessibility, and regions involved in the olig-omerization of both states of the T domain in solution.ResultsMonitoring ... mono-meric T domain and TH5 is protected because it isinvolved in the dimer interface. TH9 can be consideredas involved in the protein core but to a lesser extent.Interestingly, from these...

Tài liệu Báo cáo khoa học: 3T3-L1 adipocyte apoptosis induced by thiazolidinediones is peroxisome proliferator-activated receptor-c-dependent and mediated by the caspase-3-dependent apoptotic pathway doc

... troglitazone induces apopto-sis in prostate cancer cells by directly binding to Bcl-2 and Bcl-xL [40]. Owing to its inability to bind to Bcl-2 and Bcl-xL, pioglitazone cannot induce apoptosis in these ... levels of Akt-1 protein and inhibited its phosphorylation. Thedensitometer scanning data of Akt-1 western blot areshown in Fig. S1. However, other components of thePI3K–Akt-1 signaling cascade, ... Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, ChineseAcademy of Sciences, Shanghai, ChinaIntroductionTo date, studies of...

Tài liệu Báo cáo khoa học: Golgi reassembly stacking protein 55 interacts with membrane-type (MT) 1-matrix metalloprotease (MMP) and furin and plays a role in the activation of the MT1-MMP zymogen pdf

... been found toincrease the amount of complex containing MT1-MMP and furin, and the expression of a catalyticallyinactive dominant negative furin construct affected theprocessing of pro-MT1-MMP. ... sequence for the interaction with the PDZproteins: Mint-3, AMPA binding protein and gluta-mate receptor interacting protein (GRIP). It wouldtherefore be interesting to determine whether this ... multimerization caninvolve either of the PDZ domains, as for example in glutamate receptor interacting protein 1 (GRIP1) [55]or inactivation no afterpotential D (INAD) protein[56]. However, it can also...

Tài liệu Báo cáo khoa học :Sử dụng hợp lý nguồn tài nguyên du lịch tự nhiên cho phát triển du lịch bền vững docx

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Tài liệu Báo cáo khoa học: Disulﬁde bridge regulates ligand-binding site selectivity in liver bile acid-binding proteins ppt

... respectively).Comparison of the chemical shifts of the apo and holoforms of T91C L-BABP indicated that the regionsmostly affected by binding are mainly located at theC-terminal part of the protein, at the level of ... removal of adisulﬁde bond in rat lipocalin-type prostaglandin Dsynthase slightly increased the binding afﬁnity for bio-logical ligands, by leading to a less compact barrelpocket and allowing ... M, Paci M,Zetta L, Molinari H & Cicero DO (2007) Structural and dynamic determinants of ligand binding in the ternarycomplex of chicken liver bile acid binding protein with twobile salts...

Tài liệu Báo cáo khoa học: Mixed lineage leukemia histone methylases play critical roles in estrogen-mediated regulation of HOXC13 docx

... seen in Fig. 5A, no signiﬁcant binding of actin wasobserved in any of the EREs, irrespective of theabsence and presence of E2. Binding of ERa and ERbwas increased in both ERE1 and ERE2 of theHOXC13 ... binding proﬁles in a time-dependentmanner in ERE1 and ERE2 (Fig. 5B). In agreementwith the above ﬁndings, binding of ERa and ERb wasincreased in both ERE1 and ERE2 in the presence of E2. Interestingly, ... Interestingly, the kinetics of E2-dependent binding of ERa and ERb to both ERE1 and ERE2 are differ-ent. The binding of ERa is very low in the absence of E2, and is signiﬁcantly enhanced in the...

Tài liệu Báo cáo khoa học: Bacterial-induced hepoxilin A3 secretion as a pro-inﬂammatory mediator pptx

... hepoxilin A3blocks the apical release of hepoxilin A3 in vitro and the transmigration of neutrophils induced by S. typhimurium both in in vitro and in vivo models of in ammation. Such results ... report of intracellular Ca 2+ events following HXA3administra-tion to isolated human neutrophils are consistent withthis hypothesis [3]. Most recent studies indicate thatthe Ca 2+ signaling induced ... mito-chondria [13]. In fact, HXA3has been shown to inhibitsubsequent Ca 2+ signaling events in cells where Ca 2+ signaling is normally induced by fMet-Leu-Phe, plate-let-activating factor and leukotriene...

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