FUTURE ASPECTS OF TUMOR SUPPRESSOR GENE potx

... site for a tumor suppressor gene involved in mouse thymic lymphomagen‐ esis is located on the distal part of chromosome 4. Oncogene. 1998;17(7):925-9. Future Aspects of Tumor Suppressor Gene 14 [43] Santos ... understanding of variable pathways of radiation lymphomagenesis. Future Aspects of Tumor Suppressor Gene 10 Acknowledgements We thank Ms. Yuko Mitaki...

Ngày tải lên: 23/03/2014, 17:20

... regulation of the endosomal compartment by p53 the tumor suppressor gene Xin Yu 1 , Todd Riley 2,3 and Arnold J. Levine 1,3 1 The Cancer Institute of New Jersey, University of Medicine and Dentistry of ... accumulation of errors in a cell. As part of this process, p53 regulates the transcription of a set of genes encod- ing proteins that populate the endosomal compartmen...

Ngày tải lên: 23/03/2014, 04:21

... 2010.09.03; Accepted: 2011.02.15; Published: 2011.02.21 Abstract Human tumor suppressor gene RIZ encodes two protein products, tumor suppressor RIZ1 and proto-oncoprotein RIZ2, which regulate cellular ... whereas RIZ1, a tumor suppressor, arrests cells in the G2/M phase of the cell cycle and induces apoptosis [10-12]. An imbalance in the amount of RIZ1 and RIZ2 may be...

Ngày tải lên: 25/10/2012, 11:15

... to expand the data- base of biochemical ⁄ biophysical properties of DNA adducts of cytotoxic analogues of transplatin, we des- cribed in the present work some aspects of DNA modification by trans-PtHMP ... the cytostatic effects of this new transplatin analogue. The antitumor effect of platinum complexes is believed to result from their ability to form various types of adduct...

Ngày tải lên: 16/03/2014, 14:20

... transcription of heat shock protein genes, whose products maintain protein homeostasis under normal physiological condi- tions, as well as under conditions of stress. The promoter regions of the target genes ... to and regulates basal expression via HSEs of target genes [26]. Deletion of the HSF gene is lethal to cells, even at physiological temperatures. The genes targeted by HSF...

Ngày tải lên: 18/02/2014, 04:20

... the internal side of the peanut. The results of the crystallo- graphic model of CagS do not show any clear evidence of architectural similarity to other known structures, with the exception of a weak ... and DcagA isogenic mutant strains of H. pylori provided preliminary evidence that these genes could be involved in the repression of the gene coding for the catalytic subunit...

Ngày tải lên: 06/03/2014, 00:21

... JUDGMENTS OF THE COURT OF APPEAL OF NEW ZEALAND ON PROCEEDINGS TO REVIEW ASPECTS OF THE REPORT OF THE ROYAL COMMISSION OF INQUIRY INTO THE MOUNT EREBUS AIRCRAFT DISASTER Table of Contents ... conduct of certain officers of Air New Zealand. Senior officers of the airline are severely criticized in the Report and in one paragraph on the basis of "a pre-d...

Ngày tải lên: 06/03/2014, 12:21

Ngày tải lên: 08/03/2014, 16:20

... with p16 INK4a expression. Of note, these two cell lines give insight into the specificity of the effect as a result of their differences in the status of the retinoblastoma tumor- suppressor gene, pRb. Increased ... elegant orchestration of gene expression for glycosyltrans- ferases and galectin-1 with functional consequence. The general tissue-specific manner of expression...

Ngày tải lên: 16/03/2014, 10:20

... two of them, by deletion of the central repetitive domain. To establish the nature of the mechanisms responsible for the diversity of MUC4 transcripts, the genomic structure of the 3¢ region of ... region but also for two of them by deletion of the central repetitive domain. Until now, because of the lack of knowledge on the genomic organization of the 3¢ region of MUC...

Ngày tải lên: 17/03/2014, 23:20