Báo cáo khoa học: Advances in functional protein microarray technology Paul Bertone and Michael Snyder doc

Báo cáo khoa học: Advances in functional protein microarray technology Paul Bertone and Michael Snyder doc

Báo cáo khoa học: Advances in functional protein microarray technology Paul Bertone and Michael Snyder doc

... time and complexity involved with the cloning and purification of individual proteins as a prerequisite to constructing functional protein microarrays. In terms of assessing protein protein interactions, protein ... preparing hun- dreds or thousands of individual protein samples, the proteins must remain active during the manufacture and probing of microarrays. This entails k...

Ngày tải lên: 23/03/2014, 15:21

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Tài liệu Báo cáo khoa học: Histones in functional diversification Core histone variants pdf

Tài liệu Báo cáo khoa học: Histones in functional diversification Core histone variants pdf

... blocks in the N-terminus and histone fold of Cid may mediate essential protein protein interac- tions for recruitment of other centromeric proteins, neutralize phosphates in linker DNA and further ... containing poly(ADP-ribose) polymerase activity and other single strand RNA viral proteins. They show structural similarity to the DNA binding domain of leucine aminopeptidases, sugg...

Ngày tải lên: 20/02/2014, 02:22

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Báo cáo khoa học: "Advances in Discriminative Parsing" potx

Báo cáo khoa học: "Advances in Discriminative Parsing" potx

... regularization penalty by decreasing λ (Steps 1.6 and 1.7) and continue training. In this way, instead of choosing the best λ heuristically, we can optimize it during a single training run (Turian & ... set as training progressed. Even though the baseline training made progress more quickly than the kitchen sink, the kitchen sink’s F 1 surpassed the baseline’s F 1 early in trainin...

Ngày tải lên: 08/03/2014, 02:21

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Báo cáo khoa học: "TYPES IN FUNCTIONAL UNIFICATION GRAMMARS" ppt

Báo cáo khoa học: "TYPES IN FUNCTIONAL UNIFICATION GRAMMARS" ppt

... Towards Functional Logic Grammars. In Dahl, V. and Saint-Dizier P. (Ed.), Natural Language Programming and Logic Programming, II. Amsterdam: North Holland. Elhadad, Michael. (1988). The FUF Functional ... INTRODUCTION Unification-based formalisms are increasingly used in linguistic theories (Shieber, 1986) and com- putational linguistics. In particular, one type of u...

Ngày tải lên: 24/03/2014, 02:20

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Tài liệu Báo cáo khoa học: "Evaluation of Machine Translations by Reading Comprehension Tests and Subjective Judgments" doc

Tài liệu Báo cáo khoa học: "Evaluation of Machine Translations by Reading Comprehension Tests and Subjective Judgments" doc

... translations for preliminary tests and advised on prepa- ration of the final text, and to D. B. Robinson, Jr., L. Rosier, and B. J. Kinsberg for their contributions to selection of passages and preparation ... but with a feeling of uncertainty as to whether it was the intended interpretation. Subjects in the first study judged the sentences in paragraphs. It was intended as...

Ngày tải lên: 19/02/2014, 19:20

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Báo cáo khoa học: Typical 2-Cys peroxiredoxins – modulation by covalent transformations and noncovalent interactions doc

Báo cáo khoa học: Typical 2-Cys peroxiredoxins – modulation by covalent transformations and noncovalent interactions doc

... The PAG gene prod- uct, a stress-induced protein with antioxidant proper- ties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activity. Genes Dev 11, 2456–2467. 91 ... the protein that inhibits the intrinsic tyrosine kinase activity of the oncoprotein c-Abl [90]. Later, the study of the cytosolic yeast 2-Cys Prxs, cPrx1 and cPrx2, was extremely...

Ngày tải lên: 07/03/2014, 00:20

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Báo cáo khoa học: Reaction of human UMP-CMP kinase with natural and analog substrates docx

Báo cáo khoa học: Reaction of human UMP-CMP kinase with natural and analog substrates docx

... substrates, in particular at the acceptor site, including deoxycytidine kinase, human mitochondria thymidine kinase 2 and herpes thymidine kinase 1 and 2 [27–29]. Only human deoxycyti- dine kinase ... Biosciences) in Tris/HCl 50 m M , pH 7.5 containing 200 m M KCl and 1 m M dithiothreitol, using bovine albumin, ovalbumin and chymotrypsinogen as markers. The elution volume of UMP-C...

Ngày tải lên: 08/03/2014, 02:20

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Báo cáo khoa học: "Word classification based on combined measures of distributional and semantic similarity" docx

Báo cáo khoa học: "Word classification based on combined measures of distributional and semantic similarity" docx

... knowledge for processing the semantics of words and documents. However, maintaining a thesaurus so that it sufficiently covers the lexicon of novel text data requires a lot of time and effort, which ... it first determines a set of k nearest neigh- bors according to the similarity metric and as- Learning Accuracy (Hahn and Schattinger 1998) as an evaluation measure is described in...

Ngày tải lên: 08/03/2014, 21:20

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Báo cáo khoa học: "Syntax-based Statistical Machine Translation using Tree Automata and Tree Transducers" doc

Báo cáo khoa học: "Syntax-based Statistical Machine Translation using Tree Automata and Tree Transducers" doc

... Graehl, Kevin Knight, Daniel Marcu, Steve DeNeefe, Wei Wang, and Ignacio Thayer. 2006. Scalable inference and training of context-rich syntactic translation models. In Proceed- ings of the 21st International ... pair (using morphological informa- tion) showed that it improved the results in terms of BLEU (Papineni et al., 2001) and NIST (Dod- dington, 2002) scores, as shown in Tab...

Ngày tải lên: 23/03/2014, 16:20

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Báo cáo khoa học: Nucleocytoplasmic shuttling of STAT transcription factors Thomas Meyer and Uwe Vinkemeier doc

Báo cáo khoa học: Nucleocytoplasmic shuttling of STAT transcription factors Thomas Meyer and Uwe Vinkemeier doc

... recognition and phosphatase recruitment for some STATs [2–5]. The N-domain is followed by a coiled-coil domain implicated in protein protein interactions [6], a DNA binding domain [7], a linker domain ... role of STAT proteins in cytokine signaling. Upon binding of extracellular ligands such as interferons or interleukines to their cognate receptors, re ceptor-asso ciated Janus kinas...

Ngày tải lên: 30/03/2014, 15:20

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