Báo cáo khoa học: Modules, multidomain proteins and organismic complexity ppt

... 272 (2005) 5064–5078 ª 2005 FEBS Modules, multidomain proteins and organismic complexity Hedvig Tordai, Alinda Nagy, Krisztina Farkas, La ´ szlo ´ Ba ´ nyai and La ´ szlo ´ Patthy Institute of ... occurring in at least one multidomain protein; e domains occurring only as stand-alone domains in single domain proteins. Proteins a Domains b Multidomain proteins c (% of pr...

Ngày tải lên: 23/03/2014, 15:21

... (CAD); and (d) a search of the resulting tandem mass spectra against a database of spectra predicted for tryptic peptides of all known pro- teins. Thousands of proteins in cultured cells, tissues and ... Hart [11], this modification is found on proteins in both the nucleus and cytoplasm, is added and removed by transferase and O-GlcNAcase enzymes, respectively, and often occurs...

Ngày tải lên: 18/02/2014, 16:20

... domain, and the C-terminal GED (Fig. 2). Obvious PRDs or PH domains are not found in DRPs. Examples of DRPs are Mx proteins, mammalian DLP1, and the yeast proteins Dnm1, Mgm1 and Vps1. Mx proteins ... tissue and liver. Its target gene products are involved in lipid catabolism such as fatty acid uptake, storage and oxidation (in peroxi- somes and mitochondria), and in lipop...

Ngày tải lên: 07/03/2014, 21:20

... buffer composition, pH and on the type and concentration of surfactant used to solubilize the substrate (which in turn affects micelle composition and dynamics), a com- parison and discussion of such ... site probes of flavoproteins. Biochem J 239, 1–12. 29 Ghisla S, Massey V, Lhoste JM & Mayhew SG (1974) Fluorescence and optical characteristics of reduced flavins and flavoprotei...

Ngày tải lên: 07/03/2014, 00:20

... models. For instance, Daum´e and Marcu’s model assumes as input a corpus annotated with both MD and coreference information. On the other hand, we tackle coreference and SC induction separately ... with 16414 proper NPs and 38227 common NPs) and the ACE test set (13444 NPs, with 3713 proper NPs and 9731 common NPs), as well as their performance on the proper NPs (row 2) and the...

Ngày tải lên: 17/03/2014, 04:20

... be handled by pretending they are a form of prepos=t=onal phrase The regular and predictable relattonsn~p between s~mple statements. ¢~uestions and relalwe clauses and between act=ve and ... effic=ency on grin ~atical ,nput. and robustness in the face of ungrammatmcal tnput Wh~le Plume ~s well adapted to s=mpte ,:;~ectaratwe and ~mperat=ve utterances, it handles 0ass=yes re...

Ngày tải lên: 31/03/2014, 17:20

... ANGPTL2 and ANGPTL6 ⁄ AGF in obesity and related metabolic diseases, and discuss the possibility that both could func- tion as molecular targets for the prevention and treatment of obesity and metabolic ... focus on the roles of ANGPTL2 and ANGPTL6 ⁄ AGF in obes- ity and related metabolic diseases, and discuss whether these ANGPTLs could be targets for the prevention and tre...

Ngày tải lên: 14/02/2014, 22:20

... coordi- nating proteins. Iron–sulfur clusters are one of the most ancient and versatile cofactors of several impor- tant class of proteins and have been implicated in vari- ety of functions [29,30]. Iron and ... biochemical and biophysical properties of WhiB2, WhiB5, WhiB6 and WhiB7 of M. tuberculosis and also compare the prop- erties of all seven WhiB proteins. We show that,...

Ngày tải lên: 18/02/2014, 12:20

... SAF34 and P4 strongly stained the di-glycosylated band, and mAbs 6H4, SAF60, SAF70 and SAF84 showed the highest staining with the overlapping bands of nonglycosylated full-length PrP C and glycosylated ... within the prion protein sequence (Fig. 1 and Table 1). The two bands of higher molecular masses are the di- and mono-glycosylated isoforms and the band with the lowest molecu...

Ngày tải lên: 19/02/2014, 02:20

... [5], and proteomics [6,7]. The presence of the vast gene cluster enables us to obtain valuable binding proteins using selection meth- odology, and recent structural visualization of candi- date proteins ... foreign peptide sequences and small scaffold proteins, and as methods for designing high-quality libraries of small scaffold proteins. Functionalization of small scaffold p...

Ngày tải lên: 06/03/2014, 11:20