Báo cáo khoa học: The astacin protein family in Caenorhabditis elegans docx

... protease domains, covering the region from Ala-1 to Leu-200 in the prototype crayfish astacin, from the C. elegans astacins and selected other astacin family members were aligned using CLUSTAL [32] ... named after their occurrence in complement components C1r/C1s, embryonic sea urchin protein Uegf, and BMP-1 [62]. These domains may be involved in calcium-binding and prote...

Ngày tải lên: 23/03/2014, 15:21

... starting points for invasion. The concerted process of opening of the initial double strand and the annealing of the new duplex finally results in either the replacement of the original strand or the ... repulsive interactions within the RNA molecule. The protein thereby smooths the folding energy landscape. The direction of the RNA folding reaction (either annealin...

Ngày tải lên: 14/02/2014, 19:20

... consonantal doubling rules in the inflection of English verbs C. The determination of word-breaking rules as used in end-of -the- line practices in type composition D. The determination of parts-of-speech ... have the property that the internal-consonant string is an ad- missible initial-consonant string. The words in Class III have the mirror image property that...

Ngày tải lên: 19/02/2014, 19:20

... extracted by the methods of the linguist than by those of the statistician. The indeterminacy which does exist in lan- guage is the indeterminacy which arises from the mapping of a continuous ... Compression In large measure the coding problems arising in MT and in library work are the same as those occurring in other branches of communi- cation engineering....

Ngày tải lên: 07/03/2014, 18:20

... (NFTs) in the brains of people with DS ⁄ AD than in the brains of people with sporadic AD (Fig. 2) [19]. DYRK1A phosphorylates tau protein at the sites that are phosphorylated in AD. In NFTs, tau protein ... DYRK1A phosphorylation of tau protein at 11 sites [20,22,43]; the DYRK1A-stimulated, several-fold increase in the rate of tau protein phosphorylation by GSK-3b...

Ngày tải lên: 22/03/2014, 16:21

... alone. The kinase-deficient mutant, OXI1 K45R , in which the lysine residue of the ATP bind- ing domain is mutated to arginine, still interacted with PTI1-4. These data indicate that the kinase ... of the input was loaded on to the gel and represents the amount of HIS-tagged proteins used for the assay. The in vitro binding assays were repeated twice using recombinant pro...

Ngày tải lên: 14/02/2014, 19:20

... with the N-terminal domain, MA, associated with the inner layer of the viral membrane, and the remaining domains forming the innermost protein layers accor- ding to their positions in Gag: MA, CA-NTD, CA-CTD, ... Spain Introduction During HIV-1 morphogenesis [1,2], the capsid protein (CA; or p24) participates in two distinct assembly events. The first occurs inside the...

Ngày tải lên: 18/02/2014, 06:20

... of both the CAI peptide and a-helix 9 of CTD during formation of the peptide– protein and protein protein complexes. These NMR experiments also allowed the determina- tion of the CTD binding site. ... 6110–6117 ª 2009 The Author Journal compilation ª 2009 FEBS Gag polyprotein, yields the matrix protein (MA), the capsid protein (CA), the nucleocapsid protein (NC) and...

Ngày tải lên: 18/02/2014, 06:20

... employing microscopic lipid-binding con- stants has previously been taken to explain the enhancement of agonist binding to the nicotinic acetylcholine receptor by general anaesthetics in terms of the ... simulate the unknown narcotic receptor(s) of tadpoles, all other parameters characterizing the nAChR lipid ⁄ protein interface remaining constant. The initial analysis assumes...

Ngày tải lên: 19/02/2014, 18:20

... multispan- ning membrane proteins, we have investigated the mechan- ism of how the sensor kinase protein KdpD inserts into the membrane. We found that KdpD inserts into the membrane independently of the ... KdpD-N. The protein was not accessible to the externally added proteinase K, indicating that it remains in the cytoplasm. Intriguingly, the formation of the dimer...

Ngày tải lên: 20/02/2014, 11:20