Báo cáo khoa học: D1 – Extracellular Matrix Proteins docx

... (OBSC) depends on (pro)insulin or insulin-like growth factor-I (IGF-I) Abstracts 282 D1 – Extracellular Matrix Proteins D1- 001 Sox9 controls both chondrocyte differentiation and proliferation B. de ... establish that integrin-mediated chondrocyte–ECM interactions are required for multiple steps of EBF. D1- 003 The matrilins – adaptor proteins in the extracellular matri...

Ngày tải lên : 23/03/2014, 15:20

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Báo cáo khoa học: Acidic extracellular pH increases calcium inﬂux-triggered phospholipase D activity along with acidic sphingomyelinase activation to induce matrix metalloproteinase-9 expression in mouse metastatic melanoma pot

... 2007) doi:10.1111/j.1742-4658.2007.05848.x Acidic extracellular pH is a common feature of tumor tissues. We have reported that culturing cells at acidic pH (5. 4–6 .5) induced matrix metalloproteinase-9 expression through phospholipase D, extracellular ... desipramine) and siRNA targeting aSMase ⁄ smpd1 could inhibit acidic extracellular pH-induced matrix metalloproteinase-9 exp...

Ngày tải lên : 07/03/2014, 09:20

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Tài liệu Báo cáo khoa học: Type I antifreeze proteins expressed in snailﬁsh skin are identical to their plasma counterparts doc

... families. Abbreviations AFGPs, antifreeze glycoproteins; AFPs, antifreeze proteins ⁄ polypeptides; IBM, ice-binding motif; ORF, open reading frame; UTR, untranslated region. FEBS Journal 272 (2005) 532 7–5 336 ª 2005 FEBS ... unlike most other known type I AFPs. Although they are extremely a-helical proteins – determined experiment- ally by CD spectrometry – they possess only mo...

Ngày tải lên : 20/02/2014, 02:22

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Tài liệu Báo cáo khoa học: Interactions between M proteins of Streptococcus pyogenes and glycosaminoglycans promote bacterial adhesion to host cells pdf

... the A–B3 region, IgGFc-binding to the S-domain, and albumin-binding to the C-repeats [31]. Recombinantly expressed fragments rA–S and rS–C3 are indicated. (D) The M1 protein and the A–S and S–C3 ... representing serotypes M1 (AP1 and 9 0–2 26), M5 and M6 (JRS4) were analysed for binding of 125 I-labelled DS. Isogenic mutants of AP1 (BM27.6, MC25, BMJ71), of 9 0–2 26 (9 0–2 26 emm1::Km),...

Ngày tải lên : 20/02/2014, 11:20

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Báo cáo khoa học: Compartmentalized signalling: Ras proteins and signalling nanoclusters pdf

... compartmen- talization of scaffold proteins that are key regulators of Ras–Raf–MAP kinase and Ras–PtdIns3K–Akt signalling. Compartmentalized scaffolds Scaffold proteins contribute to the control ... that in yeast requires class C vps proteins which are normally required to regulate endosome fusion [ 8–1 0]. Unlike other small G proteins such as Rabs and Rho proteins, there has bee...

Ngày tải lên : 07/03/2014, 00:20

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Báo cáo khoa học: 15 N-Labelled proteins by cell-free protein synthesis Strategies for high-throughput NMR studies of proteins and protein–ligand complexes doc

... proteins and proteins containing non- natural amino acids can be made efﬁciently [ 8–1 0]. With the advent of cryogenic probe heads, hetero- nuclear single quantum coherence (HSQC) spectra of proteins ... MINIREVIEW 15 N-Labelled proteins by cell-free protein synthesis Strategies for high-throughput NMR studies of proteins and protein–ligand complexes Kiyoshi Ozawa, Peter S. C. .....

Ngày tải lên : 07/03/2014, 12:20

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Báo cáo khoa học: Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting pdf

... of CD95 by matrix metalloproteinase-7 induces apoptosis resistance in tumor cells. Oncogene 23, 373 2–3 736. 29 Mitsiades N, Yu WH, Poulaki V, Tsokos M & Stam- enkovic I (2001) Matrix metalloproteinase-7-mediated cleavage ... speciﬁc gene expression. J Cell Biol 125, 68 1–6 93. 34 Rundhaug EJ (2003) Matrix metalloproteinases, angio- genesis, and cancer. Clin Cancer Res 9, 55...

Ngày tải lên : 15/03/2014, 00:20

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Báo cáo khoa học: Regulation of matrix metalloproteinase activity in health and disease pdf

... Natl Acad Sci U S A 87, 557 8–5 582. 5 Nagase H (1997) Activation mechanisms of matrix metalloproteinases. Biol Chem 378, 15 1–1 60. 6 Woessner JF Jr & Nagase H (2000) Matrix Metallo- proteinases ... Chem 272, 747 3–7 481. 117 Yu WH & Woessner JF Jr (2000) Heparan sulfate proteoglycans as extracellular docking molecules for matrilysin (matrix metalloproteinase 7). J Biol...

Ngày tải lên : 15/03/2014, 00:20

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Báo cáo khoa học: 14-3-3 Proteins regulate glycogen synthase 3b phosphorylation and inhibit cardiomyocyte hypertrophy doc

... antagonists of 14-3-3 proteins by phage display. Biochemistry 38, 1249 9–1 2504. 20 Wu CL & Muslin AJ (2002) Role of 14-3-3 proteins in early Xenopus development. Mechanisms Dev 119, 4 5–5 4. 21 Masters ... unphosphorylated motifs: GHSL and WLDLE [ 4–6 ]. 14-3-3 Proteins have been shown to interact with an array of partners, ranging from enzymes to structural proteins. Often,...

Ngày tải lên : 16/03/2014, 18:20

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Báo cáo khoa học: Activity of matrix metalloproteinase-9 against native collagen types I and III potx

... Lett 503, 15 8–1 62. 8 Ohuchi E, Imai K, Fujii Y, Sato H, Seiki M & Okada Y (1997) Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules. ... expression of collagenase-3, a novel human matrix metalloproteinase produced by breast carcinomas. J Biol Chem 269, 1676 6–1 6773. 5 Aimes RT & Quigley JP (1995) Matrix...

Ngày tải lên : 23/03/2014, 09:21

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