Báo cáo khoa học: C1–Membrane ATPases and channels doc

... inacti- vation and the slope factor for other channels were: –74.0 ± 1.7 mV* and 7.6 ± 0,4 mV*** for (R180C) –76.7 ± 1.5*** mV and 6.6 ± 0.2** mV (R834C) and –75.0 ± 1.5 mV** and 6.4 ± 0.3 mV* ... transmembrane domain. The channels were inhibited by an affinity-purified anti-CLIC1 antibody, but Abstracts 201 C1–Membrane ATPases and channels C1-001 Aquaporin Water Channels...

Ngày tải lên: 23/03/2014, 15:20

... distributions over word sequences, and in particular the model of Chelba and Je- linek (1998). Most other probabilistic shift- reduce parsing models (Briscoe and Carroll, 1993; Black et al., ... her sandwich. The model under discussion is based on shift- reduce PPDAs. In such a model, shift transi- tions generate the next word w and its associ- ated syntactic category X...

Ngày tải lên: 08/03/2014, 06:20

... supported unOer DARPA contracts #N00014-85-C-0016 and #N00014-87.C-0085. The vmws and con- clusions contained in this document ere those of the authom and should not be intecpreted as neceeserily ... "a" is anomalous and has the type NULL-SET. For more details on these formal languages and their associated type system, see the paper by Landsbergen and Scha [5]. 3...

Ngày tải lên: 31/03/2014, 18:20

... of workers ( 100) and brood ( 10), and food, water and honey ⁄ water (20 : 80 v ⁄ v) were provided. Approximately 200 pupae were injected with VgR–dsRNA1 and EGFP–dsRNA, and  150 pupae were ... microtome and placed on Superfrost PlusÔ slides (Fisher) and dried for 2 days at 39 °C. Tissue sections were dewaxed for 2 · 5 min in xylene and rehydrated serially for 10 min, each...

Ngày tải lên: 18/02/2014, 08:20

... wild-type protein (B) and the StnII-R29Q (C) and StnII-Y111N (D) variants. Blue and red correspond to positively and negatively charged areas, respectively. The side chains of R29 and Y111 are shown ... 140–147 and 159–163, not located at the membrane interaction face. These stretches partially overlap the b-hairpin composed by b-strands 145–150 and 156–161 and they are rich i...

Ngày tải lên: 14/03/2014, 23:20

... Levin 2 1 Laboratory of Cell Biology, National Heart, Lung, and Blood Institute and 2 Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of ... amide I of random coil and b-sheet structures), 1545 cm )1 (the amide II of a-helical A mode), and 1520 cm )1 (the amide II of a- helical E 1 mode), with two smaller featur...

Ngày tải lên: 17/03/2014, 03:20

... structure and dynamics of individual alanine residues in the domain [3]. PLC-d1 is comprised of five domains; PH, EF-hand, X, Y, and C2 [4–6]. The PH domain is located at the N-terminus and is known ... active site (X and Y domain) and its substrate, PIP 2 [11,12]. A study using chimeric proteins of PLC- d1 and PLC-b1 led to the proposal that the interactions between the PH domain...

Ngày tải lên: 30/03/2014, 10:20

... of permeability transition. The duration of D and R phases was 1.05 and 0.77 s, respectively. The rate of fluorescence changes in D and R phases was 15 and 12 gray valuesÆs )1 , respectively (Fig. ... of purinergic receptors and the IP 3 pathway) given at the time of acquisition of images. Drug combinations (aurovertin and oligomycin, rotenone and olygomycin, rotenone and SAD)...

Ngày tải lên: 30/03/2014, 16:20

... Because glucose is the primary fuel for the CNS and blood glucose and hypothalamic malonyl-CoA levels fall and rise together during food deprivation and refeeding, it was reasoned that glucose metabolism ... can integrate carbohydrate and lipid nutrient sensing in the brain and is an example of an enzyme that can sense and respond to the nutritional environment. The major challe...

Ngày tải lên: 14/02/2014, 22:20

... based on docking and pharmacophore models. J Chem Inf Model 45, 1101–1108. 36 Sarkhel S & Desiraju GR (2004) N–H O, O–H O, and C–H O hydrogen bonds in protein–ligand complexes: strong and weak ... electron density maps and facilitate further rebuilding and improvement of the molecular model, until no unex- plained electron density remained, and the R cryst and R free values...

Ngày tải lên: 16/02/2014, 09:20