Báo cáo khoa học: Quantitative assessment of the glyoxalase pathway in Leishmania infantum as a therapeutic target by modelling and computer simulation pot
Báo cáo khoa học: Quantitative assessment of the glyoxalase pathway in Leishmania infantum as a therapeutic target by modelling and computer simulation pot
... FEBS
Quantitative assessment of the glyoxalase pathway in
Leishmania infantum as a therapeutic target by modelling
and computer simulation
Marta Sousa Silva
1
, Anto
´
nio E. N. Ferreira
1
, Ana ... evaluating the
relevance of the glyoxalase pathway as a potential therapeutic target by
revealing the importance of critical parameters...
Báo cáo khoa học: Essential role of the C-terminus in Melanocarpus albomyces laccase for enzyme production, catalytic properties and structure pdf
... remaining attached to the Asn. The effect of
deglycosylation was analysed by SDS ⁄ PAGE and
activity measurements. A single band at 90 kDa was
detected in the deglycosylated laccase samples, in con-
trast ... to affect the folding
of the protein during the post-translational processing,
and thereby the function of the mature laccase.
Our structural analysis...
Tài liệu Báo cáo khoa học: Quantitative analysis of the experimental O–J–I–P chlorophyll fluorescence induction kinetics Apparent activation energy and origin of each kinetic step Steve Boisvert, David Joly and Robert Carpentier doc
... reducible plastoqui-
nones, on the quantitative parameters are discussed in terms of the origin
of each kinetic phase.
Abbreviations
A
O–J
, A
J–I
and A
I–P
, amplitude of O–J, J–I and I–P phases, ... is accounted for by the O–J phase. Interestingly,
this decrease of A
J–I
was compensated for by the
equivalent increase of A
O–J
, making the sum of c...
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... which of the 24 exemplars the par-
ticipant was viewing and thinking about. Sepa-
rate classifiers were also trained for classifying
the isolated nouns, the phrases, and the 4 seman-
tic categories. ... and linear trend, and were
temporally smoothed with a high-pass filter
using a 190s cutoff. The data were normalized to
the MNI template brain image using a 12-...
Báo cáo khoa học: Identification of the amniotic fluid insulin-like growth factor binding protein-1 phosphorylation sites and propensity to proteolysis of the isoforms docx
... FEBS
a mechanism for increasing the bioavailability of IGFs
by enhancing the proteolytic cleavage as well as for
producing the C-terminal domain.
We have examined the amino acid sequences of the
other ... trophoblast and
fetal–placental physiology and pathology and its level
in maternal as well as in fetal circulation and in the liver
increases under...
Báo cáo khoa học: Enzymatic features of the glucose metabolism in tumor cells ppt
... Maeda N,
Nagashima Y, Tanaka T, Yamamoto S, Oka M &
Nakamura K (2009) Detection of autoantibodies
against cyclophilin A and triosephosphate isomerase in
sera from breast cancer patients by proteomic ... of BGP has been
proposed to be a potential early biomarker for human
colorectal carcinomas [204]. By contrast, in brain
tumor tissues (astrocytoma and glioblastoma) th...
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... GAA TAC ATC GTA ggc CTC TAC CAG CAC ATG CAG-3¢ AatI
5¢R6 7A 5¢-GGT AGA GAG ATA CGA TGT ATT Cgc gAC GTT GTT TAT CTA TGA
AAA GC-3¢
NruI
3¢R6 7A 5¢-GCT TTT CAT AGA GAA ACA ACG Tcg cGA ATA CAT CGT ATC ... normalized the values
obtained in all the assays for dipeptide formation a nd for
DKP production by multiplying the counts in the radioac-
tive assays and the area in th...
Báo cáo khoa học: New members of the brachyurins family in lobster include a trypsin-like enzyme with amino acid substitutions in the substrate-binding pocket potx
... distinguished as monophyletic, the one of crayfish
(Astacidea) trypsins and a group that includes trypsins
from P. argus (Palinura), Brachyura, Penaeoidea, Cari-
dea and Euphausiacea (Fig. 5).
Although ... reliability. Backbone conformation was evaluated by
the inspection of the Psi ⁄ Phi Ramachandran plot obtained
from procheck analysis [36]. Packing quality of the 3D...
Báo cáo khoa học: Functional role of the linker region in purified human P-glycoprotein pot
... as Arg680 and Leu682,
respectively [22]. Trypsin cleavage increased the basal,
verapamil-stimulated and vinblastine-stimulated
ATPase activities, suggesting that cleavage of the
linker activates ... increased ATPase activity
also indicates that the linker region has another role
as a suppressor of ATPase activity in the native P-gp.
The k
sub
⁄ k
basal
values of na...
Tài liệu Báo cáo khoa học: Crystal structure of the cambialistic superoxide dismutase from Aeropyrum pernix K1 – insights into the enzyme mechanism and stability pdf
... to
confirm the tetrameric association in solution. In the Mn-bound form, the
metal was in trigonal bipyramidal coordination with five ligands: four side
chain atoms and a water oxygen. One aspartate and ... 100°C.
Int J Syst Bacteriol 46, 1070–1077.
10 Kawarabayasi Y, Hino Y, Horikawa H, Yamazaki S,
Haikawa Y, Jin-no K, Takahashi M, Sekine M, Baba S,
Ankai A et al. (1999) Co...