... other and facilitate aggre- gation of the tau protein. To better understand the mechanism of PHF for- mation, the effects of phosphorylation on the confor- mation and aggregation of the R4 repeat ... reveals that both tau peptides are capable of self-aggregation and that phosphorylation at Ser356 can modulate this process. Abbreviations AD, Alzheimer’s disease; PHF, paired...
Ngày tải lên: 16/03/2014, 05:20
... mori: amino acid sequence and dimeric structure. Agric Biol Chem 55, 73–86. 6 Kawakami A, Kataoka H, Oka T, Mizoguchi A, Kimura-Kawakami M, Adachi T, Iwami M, Nagasawa H, Suzuki A & Ishizaki ... gene. The axon emanating from the somata (light blue arrowheads and enlarged image shown in E) runs towards the midline of the brain with some arborization (boxed area in A) , con...
Ngày tải lên: 30/03/2014, 20:20
Tài liệu Báo cáo khoa học: Hypoxic resistance to articular chondrocyte apoptosis – a possible mechanism of maintaining homeostasis of normal articular cartilage pdf
... inhibition of cartilage and chondrocyte degeneration. Results Macroscopic and radiographic examination of the articular cartilage after experimentally induced OA Articular cartilage of the femoral condyles ... severity of synovial inflammation was graded on the basis of colour, angiogenesis and fibrillation: grade 0, no inflammation; grade 1, slight inflammation; grade 2, strong i...
Ngày tải lên: 18/02/2014, 14:20
Báo cáo khoa học: Insect cytokine, growth-blocking peptide, is a primary regulator of melanin-synthesis enzymes in armyworm larval cuticle pptx
... Yoichi Hayakawa 2 1 Graduate School of Environmental Earth Science, Hokkaido University, Sapporo, Japan 2 Department of Applied Biological Science, Saga University, Japan Animal color patterns have ... during the last larval molt [7]. Because TH is another key enzyme in the biosynthesis of Dopa and dopamine, precursors of Dopa and dopamine melanin, respectively, the predominant...
Ngày tải lên: 16/03/2014, 11:20
Báo cáo khoa học: "Modeling Human Sentence Processing Data with a Statistical Parts-of-Speech Tagger" ppt
... Region A total of 30 pairs of a garden-path sentence and its ambiguous, non-garden-path control were tested for a comparison of the probability decrease at the disambiguating region. In 80% of the ... probabil- ity re-ranking. That is, the tagger initially favors the main-verb interpretation for the ambiguous -ed form, and later it makes a repair when the ambigu-...
Ngày tải lên: 17/03/2014, 04:20
Tài liệu Báo cáo khóa học: UDPgalactose 4-epimerase from Saccharomyces cerevisiae A bifunctional enzyme with aldose 1-epimerase activity docx
... UDPglu- cose and is an important enzyme of the galactose metabolic pathway. The Saccharomyces cerevisiae epimerase encoded by the GAL10 gene is about twice the size of either the bacterial or human protein. ... doi:10.1111/j.1432-1033.2003.03974.x the Leloir pathway: galactokinase, galactose 1-phosphate uridylyltransferase, and UDPgalactose 4-epimerase. A multiple-sequence a...
Ngày tải lên: 19/02/2014, 12:20
Báo cáo khoa học: "SEMANIIC PARSING AS GRAPH LANGUAGE TRANSFORMATION A MULIIDIMENSIONAL APPROACH TO PARSING HIGHLY INFLECTIONAL LANGUAGES" docx
... chapter a graph grammar formalism based on the notions of relational graph grammars (Rajlich 1975) and attributed programmed graph grammars (Bunke 1982) is developed for parsing languages with ... An r-graph language (RGL) generated by an r-graph grammar is the set of all derivable r-graphs from any r-graph in START by any sequence of applicable r-productions of PROD:...
Ngày tải lên: 17/03/2014, 19:21
Tài liệu Báo cáo khoa học: Evidence that the assembly of the yeast cytochrome bc1 complex involves the formation of a large core structure in the inner mitochondrial membrane pdf
... hypothesis that the addition of ISP may play a pivotal role in the structural rearrangement of the yeast bc 1 complex that finally leads to the supercomplex formation. These new findings open up several avenues ... were used for the preparation and ligation of DNA fragments, for the trans- formation of Escherichia coli and for the isolation of plas- mid DNA from bacter...
Ngày tải lên: 18/02/2014, 08:20
Báo cáo khoa học: Structure of the core oligosaccharide of a rough-type lipopolysaccharide of Pseudomonas syringae pv. phaseolicola docx
... 2004 Core oligosaccharide of Pseudomonas syringae (Eur. J. Biochem. 271) 4977 Structure of the core oligosaccharide of a rough-type lipopolysaccharide of Pseudomonas syringae pv. phaseolicola Evelina ... Mild acid degradation of the LPS gave the major glycoform 1 c ore octasaccharide and a minor trun- cated glycoform 2 core heptasaccharide, which...
Ngày tải lên: 23/03/2014, 13:20
Tài liệu Báo cáo khoa học: Structure of the putative 32 kDa myrosinase-binding protein from Arabidopsis (At3g16450.1) determined by SAIL-NMR docx
... PA-oligosaccharides, GalNAca1-3(Fuca1-2)Galb1-3(Fuca1-4)GlcNAcb1-3Galb1- 4Glc-PA and Neu5Aca2-6Galb1-4GlcNAcb1-2Mana1- 6(Neu5Aca2-3Galb1-3(Neu5Aca2-6)GlcNAcb1-4(Neu5Aca2- 6Galb1-4GlcNAcb1-2)Mana1-3)Manb1-4GlcNAcb1-4Glc- NAc-PA ... glycan Neu5Aca2-6Galb1-4GlcNAcb1-2Mana1-6(Neu5- Aca2-3Galb1-3(Neu5Aca2-6)GlcNAcb1-4(Neu5Aca2-6Galb1- 4GlcNAcb1-2)Ma na1-3)Manb1-4GlcNAcb1-4GlcNA-PA was used as a...
Ngày tải lên: 18/02/2014, 14:20