Báo cáo khoa học: Solution structure of long neurotoxin NTX-1 from the venom of Naja naja oxiana by 2D-NMR spectroscopy pot
Báo cáo khoa học: Novel c-carboxyglutamic acid-containing peptides from the venom of Conus textile docx
... ion
mass spectrum of the doubly charged ion at m ⁄ z ¼
660.18. The isotopic distribution of the b
2
ion (inset)
indicates the presence of bromine. The MS ⁄ MS
spectrum allows assignment of the sequence
SW*NCYNGHCTG, ... methyl-esterification of the
fragment (Fig. S3). The presence of six cysteinyl resi-
dues was confirmed by observation of an average mass
increme...
Tài liệu Báo cáo khoa học: Erythrochelin – a hydroxamate-type siderophore predicted from the genome of Saccharopolyspora erythraea docx
... characterization of these compounds is
growing and may result in the synthesis of specific
inhibitors based on the structure of the pathogen
siderophore [16].
A promising approach for the isolation of secondary
metabolites, ... composed of a hOrn and a haOrn moiety.
Furthermore, a long- range
1
H–
13
C correlation was
detected between the carbonyl carbon of the serin...
Báo cáo khoa học: A Kazal prolyl endopeptidase inhibitor isolated from the skin of Phyllomedusa sauvagii pdf
... for each concentration of the
inhibitor by nonlinear fit of the data from the above
negative controls; [I] is the concentration of the inhibitor,
IC
50
is the concentration of inhibitor that causes ... 7.4. Then, proteolysis was started by the addition of
50 lLof10mgÆmL
)1
a-casein. At different time-points,
60 lL aliquots were withdrawn and the reaction was
sto...
Báo cáo khoa học: Solution structure of long neurotoxin NTX-1 from the venom of Naja naja oxiana by 2D-NMR spectroscopy pot
... Solution structure of long neurotoxin NTX-1 from the venom
of
Naja naja oxiana
by 2D-NMR spectroscopy
Mehdi Talebzadeh-Farooji
1
, Mehriar Amininasab
1
, ... revealed that the solution structure
is more flexible in the tip of loop II [14].
Here we report the elucidation of solution structure of
neurotoxin- 1 (NTX-1; P01382, from Naja naja...
Tài liệu Báo cáo khoa học: Solution structure of hirsutellin A – new insights into the active site and interacting interfaces of ribotoxins docx
... mecha-
nism of transphosphorylation, which implies the
A
B
Fig. 3. Stereo diagram of the active center
of HtA. (A) Superposition of the active-site
residues of the 20 conformers of the solu-
tion structure ... electrostatically with the other
charged groups. In the NMR structures, this side
chain of D40 is a short distance (£ 3A
˚
) from the side
chains of...
Tài liệu Báo cáo khoa học: Solution structure of crotamine, a Na+ channel affecting toxin from Crotalus durissus terrificus venom docx
... fact, in the
structures of Crt, the side-chain of Phe 25 is close enough to
the amide proton of Lys38 to induce a ring current effect.
Description of the toxin structure and potential surface
The ... doi:10.1046/j.1432-1033.2003.03563.x
To the best of our knowledge, this is the first report on the
solution structure of a toxin from snake venom active on
Na...
Tài liệu Báo cáo khoa học: Solution structure of the matrix attachment region-binding domain of chicken MeCP2 ppt
... [15].
The solution structure of the MBD of rat (r)MeCP2 has
recently been determined [17]. The MBD adopts a wedge-
shaped structure, composed of an antiparallel b-sheet on
one face of the wedge ... one-turn helix on the other face. It is thought
that the two inner strands of the b-sheet lie within the major
groove of the DNA and that a hydrophobic pocket for...
Báo cáo khoa học: Solution structure of the catalytic domain of RICH protein from goldfish pot
... similarity of the structures. The lowest-energy structure from the
RICH NMR ensemble is used for the overlay. (D) The surface of the RICH catalytic domain shows several negatively charged patches of ... occupied by the longest
helices a1 and a9. A number of short helical fragments
group together in the vicinity of the N-terminus. This
helical patch is the m...
Báo cáo khoa học: Solution structure of the active-centre mutant I14A of the histidinecontaining phosphocarrier protein from Staphylococcus carnosus ppt
... towards the
interior of the protein. The space that in the wild-type
molecule is occupied by the large hydrophobic side chain of
Fig. 3. Structure ensemble of HPr(I14A). The average structure of the
10 ... was
computed as the ratio of the s tandard deviations of the
chemical shifts of the amide nitrogen and p roton nuclei.
Results
Determination of...
Báo cáo khoa học: Solution structure and backbone dynamics of the XPC-binding domain of the human DNA repair protein hHR23B docx
... vectors
along the peptide chain. We analyzed the diverse
hydrophobic surfaces of XPCB–hHR23B, which result
from the flexible N-terminal region, and attempt to
determine the structure of the XPC-binding ... or kinks (Figs 1
and 2A). The N-terminal part of XPCB–hHR23B
ABC
Fig. 2. NMR structure of the XPCB domain of hHR23B. (A) Stereoview of the 12 superimposed s...