Báo cáo khoa học: Structural model for an AxxxG-mediated dimer of surfactant-associated protein C pptx

... Structural model for an AxxxG-mediated dimer of surfactant-associated protein C Visvaldas Kairys 1 , Michael K. Gilson 1 and Burkhard Luy 2 1 Center for Advanced Research in Biotechnology Rockville, ... resistance to CNBr cleavage and dual NMR resonances of porcine and human recombinant SP -C with Met32 replaced by isoleucine point to a dimerization site located at th...

Ngày tải lên: 23/03/2014, 12:20

... ¢-CCGCGGCTAGCTGTTC ACATTCTCAATG-3¢ (MRP2D3), 5¢-CCGCGGCTACT CAATGCCAGCTTCCTT-3¢ (MRP2D7), 5¢-CCGCGG CTATTCCTTAGCCATAAAGTAAAA-3¢ (MRP2D11), 5¢-CCGCGGCTAAAAGTAAAAGGGTCCAGGG-3¢ (MRP2D15), 5¢-CCGCGGCTAAGGGATTTGTAGCA GTTCT-3¢ ... (MRP2D11), 5¢-CCGCGGCTAAAAGTAAAAGGGTCCAGGG-3¢ (MRP2D15), 5¢-CCGCGGCTAAGGGATTTGTAGCA GTTCT-3¢ (MRP2D20), 5¢-CCGCGGCTATTCTTCA GGGCTGCCGC-3¢ (MRP2D25), 5 ¢-CCGCGGCTATTC CTTA...

Ngày tải lên: 31/03/2014, 09:20

... "}- E E Cw'(da,tk,p, tc) tcGTc( tk ,dA,dB ) P =1 where cw and cw' are scores of importance for co- occurrence of words, tk and t~. Intuitively, cw and cw' are counter ... difference between cw and cw' is the following, cw is calculated for each noun. On the other hand, cw' is calculated for each combination of noun and its case i...

Ngày tải lên: 20/02/2014, 18:20

... occupancy. The concomitant occurrence of ligand and water mole- cules (also refined at 50% occupancy) at almost identi- cal positions might lead to increased coordinate errors during the refinement of the ... comparison of the ligand positions of tetracycline, dox and atc in TetR, these ligands superimpose with an average rmsd of 0.26 A ˚ for 27 common ligand atoms. In the case o...

Ngày tải lên: 16/03/2014, 00:20

... buffer. 5′ CTAGAGGATCC T 5′ CTAGAGGATCC T 3′ TCCTAGG T 3′ TCCTAGG U U1-hairpin U3-hairpin 5′ CTAGAGGATCC U 5′ CTAGAGGATCC T 3′ TCCTAGG T 3′ TCCTAGG T U2-hairpin U4-hairpin U T T T U T T T Scheme 1. Table ... dihedral angles that facilitate the loop formation are b of T 12 and T 13 , c of T 13 and c, e and f of U14 and perhaps be to a certain extent c of T 15 , all of which adop...

Ngày tải lên: 31/03/2014, 09:20

... each other in HeLa and transfected COS cells. (A) Colocalization of Clip 170 and Anp32a in COS cells that were transfected with a plasmid vector carrying V5-tagged Clip 170 and c- Myc-tagged Anp32a. ... UK The leucine-rich repeat acidic nuclear protein (Anp32a ⁄ LANP) is a member of the Anp32 family of acidic nuclear evolutionarily-conserved phosphoproteins, which present a broad ran...

Ngày tải lên: 18/02/2014, 17:20

... Information Technology Center, Kagawa University, Japan Cyclodextrins (CDs) are cyclic a-1,4-glucans, and the central cavity of CDs can host a large number of che- micals by hydrophobic interaction [1]. ... bindable form, designated a closed form. The TvuCMBP c- cyclodextrin complex structurally resembles the closed form of EcoMBP, indicating that TvuCMBP complexed with c- cyclodextrin...

Ngày tải lên: 19/02/2014, 00:20

... recordings are transcribed with the transcrip- tion tool ELAN 1 , using an orthographic transcrip- tion. All in all 3590 driver utterances and 4382 passenger utterances are transcribed. An annota- tion ... which contained redundant information when comparing with the last utterance before the interruption, and those which did not contain and redundant infor- mation. As a redundant utteran...

Ngày tải lên: 20/02/2014, 04:20

... lexical instantiations of a syntactic-semantic struc- ture. If we decide to view subtrees as identical iff their syntactic structure, the semantic rule at each node, and the semantic type of ... the face of phenomena such as non-standard quantifier scope or discontinuous constituents cre- ates complications in the syntactic or semantic anal- yses assigned to certain sentences a...

Ngày tải lên: 22/02/2014, 03:20

... extensively for speech recogni- tion (Paxton 1977, Walker et al 1978) and in the field of expert systems (such as Mycin, Buchanan & Shortliffe 1984), where the calculation of both score and ranking ... interpretations of the same object. According to this definition the scor- ing and ranking mechanism described in the previous section is a case of preference. In the res...

Ngày tải lên: 22/02/2014, 10:20