Báo cáo khoa học: The oxidation process of Antarctic fish hemoglobins pot

... carbomonoxy form of the protein to 6.0 [19]. In the early stages of the oxidation process (2–9 h, Fig. 3) the exposure of HbTbCO to air leads to the formation of the deoxy form, as suggested by the appearance ... atoms aremeasuredineachmodel.Thedifferencesinthe corresponding Ca distances between the two models are then evaluated and used as elements of the matr...

Ngày tải lên: 23/03/2014, 12:20

... identity to the H ad - FABP or H6-FABP from Antarctic fishes and the putative orthologs from other teleost fishes (83–88%). Phylogenetic analysis clustered the zebrafish FABP4 with all Antarctic fish H6-FABPs ... with the exception of zebrafish fabp1a, which contains an additional intron in the 5¢- UTR [20]. The nucleotides at the splice site of each exon–intron junction...

Ngày tải lên: 07/03/2014, 10:20

... matched in any other way; thus if the parser chooses too iarge a vertex cover, the U- symbols will not match and the parse will fail. The proper number of D-symbols equals the length of the input ... to process. ~ The factors making languages EP would not be part of grammatical theory because they would represent extragrammatical factors, i.e. the resource lim- it...

Ngày tải lên: 24/03/2014, 01:21

... distinguishing the mechanisms involved in terms of the textual function of linguistic means with respect to the different layers of the text re- presentation. In our model the units of the layer of thematic ... the actual se- quence of the textual presentation, the dynamic of discourse, i.e. the growth of the view during the ongoing discourse, is...

Ngày tải lên: 01/04/2014, 00:20

... intravenous lines). The observers were not involved in the daily care of the patients, and ICU physicians were not aware of this part of the observation. As a consequence, the clinical relevance of the predefined ... for other infections, and the absence of radiological signs of pulmonary congestion might have resulted in another fluid therapy regimen. We did not sco...

Ngày tải lên: 25/10/2012, 10:39

... turns of the DNA double helix yields binding of the two or three NF-Y complexes on the same side of the DNA. Conservation of spacing is required for optimal pro- moter activity because changing the ... site in activating the Cdc2 promoter. Binding of the activating E2Fs during the cell cycle to the promoter alternates with binding of E2F4 in quies- cent cells. Mu...

Ngày tải lên: 16/02/2014, 09:20

... helix 4 of the NTD of a neighboring subunit in the hexamer. Additional contacts involve helix 11 of the CTD and the C-terminal end of helix 7 of the NTD of the neigh- boring subunit. The NTD–CTD ... model of the NTD hexamer from MLV, the superimposed model of the NTD hexamer from HIV-1, the high-resolution X-ray model of the modified CA hexamer from HI...

Ngày tải lên: 18/02/2014, 06:20

... which corresponds to the a-helix 7 of NTD. This region is important for the formation of CA hexamers [6]; there- fore, this peptide could inhibit the formation of the hexamers, and assembly of the HIV-1 ... the X-ray structure of the nonmu- tated-CTD–CAI complex [28] (Fig. 2A, main panel). The aromatic moiety of Phe3, together with Leu6 and Ile1, are the residues...

Ngày tải lên: 18/02/2014, 06:20

... Furthermore, the pro-peptide of GDF-8 impairs interaction of the mature part with its receptors [16]. In the case of BMP-9, the pro-pep- tide appears not to alter significantly the activity of the mature ... biological function of the pro-form of bone morphogenetic protein-2 (BMP-2), a member of the transforming growth factor b (TGFb) ⁄ BLP superfamily. The role...

Ngày tải lên: 18/02/2014, 06:20

... present for the last four residues at the C-terminus. The stereochemistry of the model has been assessed using the program procheck [23]. Ninety per cent of the residues fall in the most favoured regions ... understanding of the ACMSD catalytic mechanism is still incomplete. In light of the reported ACMSD upregulation in the liver of streptozotocin-induced diabet...

Ngày tải lên: 18/02/2014, 06:20