Báo cáo khóa học: Genetic defects in fatty acid b-oxidation and acyl-CoA dehydrogenases Molecular pathogenesis and genotype–phenotype relationships ppt
Báo cáo khóa học: Genetic defects in fatty acid b-oxidation and acyl-CoA dehydrogenases Molecular pathogenesis and genotype–phenotype relationships ppt
... the world for providing genetic and cell material for the studies and certain of them for inspiring discussions concerning genotype–phenotype interactions in especially the acyl-CoA dehydrogenase ... short-chain acyl-CoA dehydrogenase gene. Mamm. Genome 8, 922–926. 482 N. Gregersen et al. (Eur. J. Biochem. 271) Ó FEBS 2004 MINIREVIEW Genetic defects in fatty acid b-ox...
Ngày tải lên: 23/03/2014, 12:20
Báo cáo khoa học: Differential regulation of fatty acid amide hydrolase promoter in human immune cells and neuronal cells by leptin and progesterone pdf
... Jarai, Z.,Fezza,F.,Miura,G.I.,Palmiter,R.D.,Sugiura,T.&Kunos, G. (2001) Leptin-regulated endocannabinoids are involved in maintaining food intake. Nature 410, 822–825. 11. Harvey, J . & Ashford, M.L. (2003) Leptin in the CNS: much more than ... m M L -glutamine and 1% nonessential amino acids [18]. Both CHP100 and U937 cells were maintained at 37 °Cin humidified 5% CO 2 atmosph...
Ngày tải lên: 30/03/2014, 15:20
Báo cáo khoa học: Escherichia coli cyclopropane fatty acid synthase Mechanistic and site-directed mutagenetic studies potx
... containing an engin- eered ribosome binding site [31] and a His 6 -tag was constructed using PCR-based recombinant technology and cloned into a pET-24(+) vector. A C-terminal tagged protein was ... monomer were titrated in one hour with triphasic kinetics. Three cysteines reacted within 4 min, two more cysteines reacted more slowly within 40min,andonecysteinereactedinathirdveryslowphase...
Ngày tải lên: 07/03/2014, 16:20
Báo cáo khoa học: N-Methylation in polylegionaminic acid is associated with the phase-variable epitope of Legionella pneumophila serogroup 1 lipopolysaccharide pptx
... Similarities in the biosynthesis pathway of legionaminic acid and neuram- inic acid (5-amino-3,5-dideoxy- D -glycero- D -galacto-non-2- ulosonic acid) have been described previously [17]. In strains belonging ... (N-acetyl- D -glucosamine); QuiNAc, 2-acetamido-2,6-dideoxy- D -glucose (N-acetyl- D -quinovosamine); Rha, L -rhamnose; Leg and 4e -Leg, derivatives of legionaminic and...
Ngày tải lên: 08/03/2014, 10:20
Báo cáo khoa học: Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics pdf
... lysines in both cases), selective inhibitors against aldolase [24] and phosphofructokinase [25] have been developed. Despite bearing chemically reactive groups, by combining high affinity and ... form, including one containing a novel metal binding site. Furthermore, they show structural heterogeneity in their inhibitor-bound forms, highlight- ing the potential to extend future inhibit...
Ngày tải lên: 23/03/2014, 07:20
Báo cáo khoa học: Mitochondrial biogenesis in mtDNA-depleted cells involves a Ca2+-dependent pathway and a reduced mitochondrial protein import pdf
... behavior and gene expression can be observed depending on mtDNA defects. Indeed, in rho-cells, Tom20 and Tim23 protein levels were reduced whereas mtHSP70 was induced, leading to a small increase in ... transcript encoding the b-subunit of the Fo-F1-ATPase, Tim44 and COXVb was determined by real-time PCR using SYBR green staining and normalized for TBP (TATA-box binding protein)...
Ngày tải lên: 23/03/2014, 15:21
Báo cáo khoa học: "Predicting Barge-in Utterance Errors by using Implicitly Supervised ASR Accuracy and Barge-in Rate per User" pot
... way of improving performance. In another aspect in dialogue systems, cer- tain dialogue patterns indicate that ASR results in certain positions are reliable. For exam- ple, Sudoh and Nakano (2005) ... correctly interpreted or not by integrating the user’s current ASR accuracy and barge -in rate. 2.2 Estimating ASR Accuracy by using Implicitly Supervised Labels To perform runtime pr...
Ngày tải lên: 23/03/2014, 17:20
Tài liệu Báo cáo khoa học: Emerging pathways in genetic Parkinson’s disease: Autosomal-recessive genes in Parkinson’s disease – a common pathway? docx
... kinase 2 (LRRK2) and ATP13A2. Mutations in the genes encoding a-synuclein, LRRK2 and ATP13A2 cause autosomal-dominant forms of parkinsonism. Mutations in the genes encoding Parkin, DJ-1 and PINK1 ... kinases including casein kinase 1, protein kinase A, protein kinase C [86] and cyclin-dependant kinase 5 [87]. Phos- phorylation of Parkin by CDK5 may regulate its ubiqu- itin-ligase...
Ngày tải lên: 18/02/2014, 14:20
Tài liệu Báo cáo khoa học: Emerging pathways in genetic Parkinson’s disease: Potential role of ceramide metabolism in Lewy body disease pptx
... substantia nigra. In addition, typical PD cases have intracellular proteinaceous inclu- sions called Lewy bodies and Lewy neurites in the brainstem and cortical areas. Genetic research in the past ... MINIREVIEW Emerging pathways in genetic Parkinson’s disease: Potential role of ceramide metabolism in Lewy body disease Jose Bras 1,2 , Andrew Singleton 1 , Mark R. Cookson 3...
Ngày tải lên: 18/02/2014, 14:20
Báo cáo khoa học: Deficiency in apolipoprotein E has a protective effect on diet-induced nonalcoholic fatty liver disease in mice pot
... P (1984) Turnover and splanchnic metabolism of free fatty acids and ketones in insulin-dependent diabetics at rest and in response to exercise. J Clin Invest 73, 1367–1376. 31 Voshol PJ, Rensen PC, ... to NAFLD. In vitro and in vivo studies have shown that lipopro- tein-bound apoE is the natural ligand for LDLr [26,32], which is the main receptor involved in the clearance...
Ngày tải lên: 05/03/2014, 23:20