Báo cáo khóa học: Large aggregating and small leucine-rich proteoglycans are degraded by different pathways and at different rates in tendon pot

... Large aggregating and small leucine-rich proteoglycans are degraded by different pathways and at different rates in tendon Tom Samiric, Mirna Z. Ilic and Christopher J. Handley School ... work shows that the pathways of catabolism for large aggregating and small leucine-rich proteoglycans are different in tendon and this may reflect the...

Ngày tải lên: 23/03/2014, 12:20

... effect being efficiently increased by a cathepsin B ⁄ cathepsin D pretreatment. The data show a novel processing pathway for internalized ETA, involving cathepsins B and D, resulting in the production ... generated by cathepsin B and cathepsin D. (A) Native ETA (10 lg) was incubated with bovine cathepsin B or cathepsin D (5 UÆmL )1 Æmg )1 ), or a mixture of both, at 37 °C for the i...

Ngày tải lên: 18/02/2014, 04:20

... glutathione and by cysteine residues in the active sites of pro- teins such as thioredoxin and peroxiredoxin. In addition, there are thiols exposed on protein surfaces that are not directly involved ... pre- pared by disruption of bovine heart mitochondria in a blen- der, followed by collection and washing by centrifugation [45]. These preparations had negligible matri...

Ngày tải lên: 06/03/2014, 09:22

... investigate the effect of sCLU and Bcl-2 overexpression on VOSO 4 -induced apoptosis of HaCaT cells, DNA and proteins were isolated from floating and attached HaCaT Neo T , HaCaT sCLU and HaCaT ... genes induced by proteinuria and identified using DNA microarrays. Clin Exp Nephrol 12, 181– 188. 77 Perkins ND (2007) Integrating cell signalling pathways with NF-jB and IKK function...

Ngày tải lên: 16/03/2014, 02:20

... disrupted by sonication and centrifuged (14 000 g for 10 min at 4 °C). (NH 4 ) 2 SO 4 was added to the supernatant (30% saturation, 10 min centri- fugation at 14 000 g at 4 °C), the pellet dissolved in ... thermal denaturation of NblA (C) and CD spectra at various temperatures and after recooling (D). (A) The spectra were measured in 20 m M sodium phosphate buffer, pH 7.5 (...

Ngày tải lên: 08/03/2014, 10:20

... schematic map of the human GA ORF indicating the intron inser- tion site at position 436. Mutations at posi- tions 488, 800 and 916 are frequently associated with the most common lysosomal degradation ... GA band; RNA 4, major DiGIR2 AGU and DiGIR2DP9.2 AGU band. Additional bands result from degradation of RNA during incubation at trans-splicing and RPA hybridization conditions....

Ngày tải lên: 23/03/2014, 13:20

... a-lactalbumin (0.5 mgÆmL )1 ) or bovine insulin (0.25 mgÆmL )1 ) were incu- bated at 37 °Cin50mm phosphate buffer, pH 7.2, contain- ing 100 mm NaCl, and aggregation and precipitation was initiated by ... precipi- tation of insulin at intermediate and high concentra- tions, and it also increased the activity of aB-crystallin in preventing the aggregation leading to amyloid fibri...

Ngày tải lên: 18/02/2014, 16:20

... for learning by reading. In AAAI Spring Symposium on Learning by Reading and Learning to Read. Andrew McCallum and Ben Wellner. 2004. Conditional models of identity uncertainty with application ... link anal- ysis, and inference. In International Conference on Intelligence Analysis (ICIA). Nader H. Bshouty and Philip M. Long. 2010. Find- ing planted partitions in nearly line...

Ngày tải lên: 07/03/2014, 22:20

... conversion, focusing on the usage of large scale collocation data. In chapter 2, descriptions of the collocations used in our sys- tem and their classification are given. In chapter 3, the ... The latter is further classified into two kinds: uninter- ruptible collocations, whose concurrence relation- ship of words are so strong that they can be dealt with as single words...

Ngày tải lên: 08/03/2014, 05:21

... annotation principles, one for non-coordinate configurations, one for coordinate configurations, one for traces (long distance depen- dencies) and a final ‘catch all and clean up’ phase. Distinguishing ... relative subcat- egorization frequency for individual predicates”. In contrast, the system of (Briscoe and Carroll, 1997) distinguishes 163 verbal subcategorisation classes by means...

Ngày tải lên: 17/03/2014, 06:20