Báo cáo khoa học: The hemoglobin genes of Drosophila ppt
... globin genes, and almost certainly reflect the ancient gene structure of the eukaryote globins [4]. Therefore, the loss and gain of introns occurred in the clade of glob1 and chironomid globin genes ... reported the unprecedented occurrence of a hemoglobin gene (glob1) in the fruitfly Drosophila melanogaster. Here we investigate the structure and evolution of the...
Ngày tải lên: 23/03/2014, 11:20
... measure of the rate of oxidation of oxyHb. RESULTS The effect of pH on the auto-oxidation of cross-linked Hb was studied. The rate of decrease of the concentration of oxyHb increased as the pH ... faster than the corresponding rough LPSs, indicating the importance of the binding of LPS to the hemoglobin. The effect of the LPS appeared to be largel...
Ngày tải lên: 08/03/2014, 10:20
... confirmed the expression trend of eight of these genes in Wnt-3a stimulated cells. The analysis of the levels of selected proteins cor- related with the northern blots with one exception. The Mrp⁄ ... factors in the genomic regions of all candidate target genes with the number of sites in control genes. We found that the genomic regions of the down-regulate...
Ngày tải lên: 30/03/2014, 16:20
Báo cáo khoa học: "The clinical value of daily routine chest radiographs in a mixed medical–surgical intensive care unit is low"
... intravenous lines). The observers were not involved in the daily care of the patients, and ICU physicians were not aware of this part of the observation. As a consequence, the clinical relevance of the predefined ... for other infections, and the absence of radiological signs of pulmonary congestion might have resulted in another fluid therapy regimen. We did not sco...
Ngày tải lên: 25/10/2012, 10:39
Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf
... turns of the DNA double helix yields binding of the two or three NF-Y complexes on the same side of the DNA. Conservation of spacing is required for optimal pro- moter activity because changing the ... site in activating the Cdc2 promoter. Binding of the activating E2Fs during the cell cycle to the promoter alternates with binding of E2F4 in quies- cent cells. Mu...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: The capsid protein of human immunodeficiency virus: intersubunit interactions during virus assembly doc
... helix 4 of the NTD of a neighboring subunit in the hexamer. Additional contacts involve helix 11 of the CTD and the C-terminal end of helix 7 of the NTD of the neigh- boring subunit. The NTD–CTD ... model of the NTD hexamer from MLV, the superimposed model of the NTD hexamer from HIV-1, the high-resolution X-ray model of the modified CA hexamer from HI...
Ngày tải lên: 18/02/2014, 06:20
Tài liệu Báo cáo khoa học: The capsid protein of human immunodeficiency virus: designing inhibitors of capsid assembly ppt
... which corresponds to the a-helix 7 of NTD. This region is important for the formation of CA hexamers [6]; there- fore, this peptide could inhibit the formation of the hexamers, and assembly of the HIV-1 ... the X-ray structure of the nonmu- tated-CTD–CAI complex [28] (Fig. 2A, main panel). The aromatic moiety of Phe3, together with Leu6 and Ile1, are the residues...
Ngày tải lên: 18/02/2014, 06:20
Tài liệu Báo cáo khoa học: The pro-form of BMP-2 interferes with BMP-2 signalling by competing with BMP-2 for IA receptor binding pptx
... Furthermore, the pro-peptide of GDF-8 impairs interaction of the mature part with its receptors [16]. In the case of BMP-9, the pro-pep- tide appears not to alter significantly the activity of the mature ... biological function of the pro-form of bone morphogenetic protein-2 (BMP-2), a member of the transforming growth factor b (TGFb) ⁄ BLP superfamily. The role...
Ngày tải lên: 18/02/2014, 06:20
Tài liệu Báo cáo khoa học: The crystal structure of human a-amino-b-carboxymuconatee-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis ppt
... present for the last four residues at the C-terminus. The stereochemistry of the model has been assessed using the program procheck [23]. Ninety per cent of the residues fall in the most favoured regions ... understanding of the ACMSD catalytic mechanism is still incomplete. In light of the reported ACMSD upregulation in the liver of streptozotocin-induced diabet...
Ngày tải lên: 18/02/2014, 06:20
Tài liệu Báo cáo khoa học: The chitinolytic system of Lactococcus lactis ssp. lactis comprises a nonprocessive chitinase and a chitin-binding protein that promotes the degradation of a- and b-chitin doc
... into the chitinolytic poten- tial of L. lactis, the present results provide only the third example of the role of family 33 CBPs in the deg- radation of recalcitrant polysaccharides. Furthermore, the ... [10]. Although the occurrence of family 33 CBPs has been known for some time [23], the present results provide only the third demonstration of the accessory fu...
Ngày tải lên: 18/02/2014, 08:20