Báo cáo khoa học: Prediction of coenzyme specificity in dehydrogenases ⁄ reductases A hidden Markov model-based method and its application on complete genomes doc

... Prediction of coenzyme specificity in dehydrogenases reductases A hidden Markov model-based method and its application on complete genomes Yvonne Kallberg 1,2 and Bengt Persson 1,2 1 IFM Bioinformatics, ... fifth major group, zinc-containing alcohol dehydrogenases, has almost as many members as the SDRs (Table 2). Transmembrane regions A number of deh...

Ngày tải lên: 23/03/2014, 10:21

... reconstruct the lysine- degradation pathway in P. aeruginosa using EC number information. As a result, we identified PA0266 as a putative 5-aminovalerate aminotransferase (EC 2.6.1.48) and PA0265 ... the lysine- degradation pathway of P. aeruginosa, because this pathway contains many missing enzymes and our understanding of the detailed enzymatic behavior in this pathway is far...

Ngày tải lên: 07/03/2014, 09:20

... from bacteria and transferred to a new Petri dish and incu- bated overnight with medium containing gentamicin. Bacterial growth of each strain was assessed by viable counts, both during initial infection ... prokaryotic evolution has created a new way to take advantage of an evolutionary ‘novel’ eukaryotic 14-3-3 protein family, using them as a necessary cofactor to activate let...

Ngày tải lên: 19/02/2014, 08:20

... order and times of elution were approximately CoQ 2 (9 min), CoQ 2 H 2 (11 min), decylQ (17 min) and decylQ 2 (22 min). The area under each peak was integrated and compared with standards containing ... h, at which point it had reached A 600  0.8 and already been sta- tionary for several hours and would remain that way for a number of days (squares). At the point indicated...

Ngày tải lên: 06/03/2014, 11:20

... and a C-terminal flavodoxin-like domain (residues 253–404) containing FMN. Two monomers assemble via a head-to-tail arrangement, such that the b-lactamase and the flavodoxin domains face each other, ... contains both irons in a similar position and an occupancy as found in the reduced state. Addition- ally, Glu85 and Asp87 adopt the conformation of the reduced state, and t...

Ngày tải lên: 07/03/2014, 10:20

... transaminase and diminishes upon forma- tion of pyridoxamine after reacting with amino group donors (the half reaction of the overall transaminase- mediated reactions). The spectrum of hKAT-I ... hour. Among the 12 a- keto acids capable of functioning as amino group acceptors for hKAT-I, a- ketobutyrate, mecapto- pyruvate and oxaloacetate showed no substrate inhibition at satura...

Ngày tải lên: 07/03/2014, 16:20

... weights w j are estimated from data. The training data for fitting these linear models is ob- tained in the following way. For each configuration (combination of language pair and domain) c and test ... there are more anchor points than pa- rameters, and also in view of the combination of inference and extrapolation in Section 6. 7 Curves on different test data for the sam...

Ngày tải lên: 07/03/2014, 18:20

... continuation argument of a i , 6) a i CAa j : a i is the continuation argument of a j , 7) a i = a j : a i and a j are labeled as the same role label, and 8) a i ∼ a j : a i and a j are labeled as the ... gold parsing data and 95.14% accuracy on Charniak automatic parsing data. Most existing SRL systems divide this task into two subtasks: Argument Identifi...

Ngày tải lên: 17/03/2014, 02:20

... TSSK3. Abbreviations AGC, containing PKA, PKG, PKC kinases family; CaMK, calmodulin-dependent protein kinase family; GA beads, glutathione agarose beads; GST, glutathione S-transferase; HA, haemagglutinin ... Bucko-Justyna et al. Characterization and regulation of TSSK3 Characterization of testis-specific serine–threonine kinase 3 and its activation by phosphoinositide-dependent kina...

Ngày tải lên: 23/03/2014, 11:20

... Fragariaxananassa UGT78D1 A. thaliana UGT8 6A1 A. thaliana UGT8 7A1 A. thaliana UGT8 3A1 A. thaliana UGT8 2A1 A. thaliana UGT8 5A1 A. thaliana SbHMNGT S. bicolor UGT76D1 A. thaliana UGT76E1 A. thaliana S39507 ... thaliana OsSGT1 O. sativa UGT74F1 A. thaliana UGT74F2 A. thaliana NtGT2 N. tabacum UGT75C1 A. thaliana UGT75B1 A. thaliana UGT75D1 A. thaliana UGT84B1 A. thaliana UGT8...

Ngày tải lên: 28/03/2014, 23:20