Báo cáo khoa học: Regulation of output from the plant circadian clock pot

... Circadian clock output in plants FEBS Journal 274 (2007) 335–345 ª 2006 The Authors Journal compilation ª 2006 FEBS 345 REVIEW ARTICLE Regulation of output from the plant circadian clock Esther Yakir, ... that the context of the motif is important. Clearly, therefore, the EE and CBS are insufficient to explain circadian expression of all the clock- E. Ya...

Ngày tải lên: 23/03/2014, 10:20

... mitochondria during apoptosis. They induce the permeabilization of the mitochondrial membrane with the release of cytochrome c and the formation of the apoptosome [38]. The major pro-apoptotic protein Bax ... particular emphasis on the induction of DNA fragmentation, which is one of the most typical characteristics of apoptosis. Regulators of DNA fragmentation On...

Ngày tải lên: 14/02/2014, 22:20

... on the regulation of all secretases mediated by all-trans-retinoic acid (ATRA), and supports the hypothesis that ATRA is capable of regulating them in an antiamyloidogenic sense at the levels of transcription, ... activities, or a combination of both. Although there is increas- ing evidence for the involvement of retinoids in Alzheimer’s disease, their significance in the...

Ngày tải lên: 16/03/2014, 01:20

... from diverse tissue sources, from tissues of differing ages and also within a single chain. Enhanced availability of data to facilitate the characterization of these structures is therefore of value. GAGs ... required as part of the examination of function for these species. Data from other GAG fragments has already proved valuable in the study of intact parent polym...

Ngày tải lên: 16/03/2014, 14:20

... chemotherapeutics has been suggested, with the aim of lowering the toxicity and enhancing the efficacy of treatments of more advanced cancers. As part of our continuing search for novel, plant- derived ... [16,17], we have evaluated a number of plants originating from differ- ent parts of the world. Physalis philadelphica is an example of such a plant. The fruit o...

Ngày tải lên: 23/03/2014, 10:20

... in the main chain of the subunit, or in the interaction of subunits within the trimer that linked the conformation of residues 120–125 to the position of the active site lip and closure of the ... observa- tion is that due to the proximity of residues 120–125 from each subunit in the centre of the trimer, the side chains of Val122 of one subunit and...

Ngày tải lên: 18/02/2014, 16:20

... rate of the autoproteolytic activation of the enzyme, together with the rate of the digestion of external peptide or protein substrates. Phosphorylation also elevates the Ca 2+ sensitivity of the ... the addition of the enzyme to the reaction mixture. From the progress curves, the rate of activation (k act ) as well as the maximal activity (v max ) of...

Ngày tải lên: 16/03/2014, 02:20

... and the lifespan of the complex by 10-fold, as judged by k off . The physiological chaperone cycle probably consists of the rapid binding of the N-terminus of the partner, regardless of whether it ... completion of the maturation process of the partner. The nature of the signal that may trigger dissociation of the complex remains unclear; however, we pr...

Ngày tải lên: 16/02/2014, 14:20

... altered [88]. These results shed light on the regulatory mechanisms steering the developmental expression pattern of HSF2, and they also provide the first example of involvement of miRNAs in the HSF ... development of the lens and maintenance of the olfactory epithelium [102]. The first evidence for a developmental function of HSF4 was provided by population genetic st...

Ngày tải lên: 18/02/2014, 04:20

... 133–138 at the exposed part of the cathepsin B molecule near the occluding loop (Fig. 2C). The location of the epitope indicates that the binding of 2A2 mAb might change the conforma- tion of the loop, ... of 161.8, 28.2 and 13.2 kDa, respectively. The formation of the cathepsin B ⁄ cystatin C complex was seen as a shift of the elution peak of cathepsin B...

Ngày tải lên: 18/02/2014, 11:20