Báo cáo khoa học: Modulation of Ca2+ entry and plasma membrane potential by human TRPM4b pptx

... Modulation of Ca 2+ entry by TRPM4b FEBS Journal 274 (2007) 704–713 ª 2006 The Authors Journal compilation ª 2006 FEBS 713 Modulation of Ca 2+ entry and plasma membrane potential by human TRPM4b Ralf ... localization in the plasma membrane, as demonstrated by confocal fluorescence microscopy. The functionality and plasma membrane localization of overe...

Ngày tải lên: 23/03/2014, 09:21

... action of EPA and DHA (Eur. J. Biochem. 271) 4465 Modulation of cyclin D1 synthesis and hyperphosphorylation of Rb by n-3 and n-6 PUFAs Induction of cyclin D1 is one of the e arliest effects of mitogenic ... Anti-mitogenic action of EPA and DHA (Eur. J. Biochem. 271) 4473 Modulation of cyclin D1 and early growth response factor-1 gene expression in interleukin-...

Ngày tải lên: 19/02/2014, 16:20

... uptake and the system y + were significantly stimulated by the addition of valinomycin (Fig. 4). The dependence of L -arginine uptake on membrane potential was further investigated by inducing membrane ... affected by L -leucine and sensitive to trans-stimulation. Moreover the activity of y + is affected by changes of membrane potential as described previously in...

Ngày tải lên: 08/03/2014, 02:20

... PRIORITY PAPER Epoxidation of benzo[ a ]pyrene-7,8-dihydrodiol by human CYP1A1 in reconstituted membranes Effects of charge and nonbilayer phase propensity of the membrane Pyotr Kisselev 1, *, ... hydrocarbo ns. To ev aluate the effect of membrane properties a nd distinct phospholipids o n t he activity of human CYP1A1 purified insect cell-expressed human CYP1A1 and o...

Ngày tải lên: 08/03/2014, 10:20

... the SV40 TAg and the C-terminus of the p180 subunit of human DNA poly- merase a-primase [26]. The genome of JCV is 69% homologous to that of SV40 and expresses an analogous set of proteins [31]. ... beforehand with a primase assay on poly (dT). Lanes 1 and 2, control reaction with DNA polymerase a-primase lacking TAg or vice versa; lanes 3 and 4, 0.2 U and 0.4 U of hu...

Ngày tải lên: 17/03/2014, 03:20

... transcription by Ca 2+ and cAMP and the maintenance of L-LTP [45]. In this work, Kovacs et al. [45] generated a membrane permeable peptide of dominant-negative TORC1. They found that acute delivery of TORC1 ... in hippocampal slices. Induction of E-LTP is marked by an arrowhead. fEPSP of time point ‘1’ and ‘2’ was compared for evaluation of E-LTP or L-LTP. Transducers...

Ngày tải lên: 30/03/2014, 08:20

... presence of 100 lM MPTP and 50 lM dopamine (F), in the presence of 200 lM MPTP and 50 lM dopamine (G), in the presence of 100 l M MPP + and 50 lM dopamine (H) and in the presence of 200 lM MPP + and ... solu- tion of ThT and the fluorescence intensity of the solu- tion was measured at 482 nm. Figure 4A shows the kinetics of aggregation of a-synuclein in the presence...

Ngày tải lên: 14/02/2014, 19:20

... mediated by the ANT in maximally polarized (forward mode of both ANT and ATPase) and maximally depolarized (reverse mode of both ANT and ATPase) mitochondria. Flux control coefficients of ANT and F 0 F 1 -ATP synthase ... difference of DWm (termed Delta phi) before and after the addition of ADP (2 mm) to WT and CYPD KO mitochondria, and cal- culated on the basis of...

Ngày tải lên: 14/02/2014, 19:20

... activity of many smooth mus- cles [1,11–13] (Fig. 1). Slow waves cause entry of Ca 2+ through opening of L-type Ca 2+ channels and contrac- tions of the smooth muscle. Cyclical release of Ca 2+ from ... cyclical release of Ca 2+ from stores can occur spontaneously and is modulated by two signals – Ca 2+ and Ins(1,4,5)P 3 ; (b) release of Ca 2+ from stores activates an...

Ngày tải lên: 16/02/2014, 09:20

... MINIREVIEW Synchronization of Ca 2+ oscillations: involvement of ATP release in astrocytes Schuichi Koizumi Department of Pharmacology, Faculty of Medicine, University of Yamanashi, Japan Introduction Glia, ... for functional contact with each other directly, and the extent and direction of the Ca 2+ wave propagation are significantly influenced by movement of the extracellu...

Ngày tải lên: 16/02/2014, 09:20