Báo cáo khoa học: The crystal structure of human WD40 repeat

Báo cáo khoa học: The crystal structure of human WD40 repeat-containing peptidylprolyl isomerase (PPWD1) pdf

... site in the cur- rent structure might be a product of an inability of the Fig. 1. Structure of PPWD1 and comparison with other Cyp structures. (A) The structure of the isomerase domain of PPWD1 ... 1A), the structure of PPWD1 is similar to the structure of the canonical CypA as well as to CypH and PPIL1, two other spliceosomal Cyps (Fig. 1B). The Ca a...

Ngày tải lên : 23/03/2014, 07:20

13
317
0

Tài liệu Báo cáo khoa học: The crystal structure of human a-amino-b-carboxymuconatee-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis ppt

... performed on the hA- CMSD crystals using the same beamline, clearly indicated the presence of a Zn metal ion bound to the enzyme. Anal- ysis of the diffraction data set allowed us to assign the crystal ... present for the last four residues at the C-terminus. The stereochemistry of the model has been assessed using the program procheck [23]. Ninety per cent of...

Ngày tải lên : 18/02/2014, 06:20

9
796
0

Tài liệu Báo cáo khoa học: The crystal structure of coenzyme B12-dependent glycerol dehydratase in complex with cobalamin and propane-1,2-diol pptx

... A ˚ resolution by the molecular replacement method. The schematic view of the overall structure is shown in Fig. 3A. Theenzymeexistsasadimeroftheabc heterotrimer. There is a noncrystallographic twofold axis ... around the center of Fig. 3A. The structure of an abc heterotrimer unit is shown in Fig. 3B. The central region of the a subunit constitutes the (b/a) 8 bar...

Ngày tải lên : 21/02/2014, 03:20

11
602
0

Báo cáo khoa học: The crystal structure of NlpI A prokaryotic tetratricopeptide repeat protein with a globular fold potx

... First, the only structures of natural TPRs in the PDB (13 TPR-containing coordi- nate sets) consist of nonglobular, extended arrays of helices [9,10,13–21]. Second, the majority of these (11 structures) ... completely independently of the rest of the protein. Here we show an alternate arrangement, in which the TPR is insepar- ably part of the whole structure. Noth...

Ngày tải lên : 07/03/2014, 16:20

14
433
0

Báo cáo khoa học: The crystal structure of annexin Gh1 from Gossypium hirsutum reveals an unusual S3 cluster Implications for cellulose synthase complex formation and oxidative stress response potx

... residue in the present structure is s omehow halfway between the loop-in and the loop-out position of the bell pepper annexin. Fig. 1. The three-dimensional structure of Anx(Gh1). (A) The fold of Anx(Gh1) ... either distorted or the access of a cation to the site is blocked by the p resence of a side chain of a b asic residue. I n case of the IIAB s ite (...

Ngày tải lên : 17/03/2014, 03:20

8
475
0

Báo cáo khoa học: The crystal structure of a xyloglucan-speciﬁc endo-b-1,4glucanase from Geotrichum sp. M128 xyloglucanase reveals a key amino acid residue for substrate speciﬁcity potx

... one end of the cleft. However, XEG lacks a corresponding loop because of deletion of those residues. The loop structure is responsible for the exo-activity of OXG-RCBH, and the absence of the loop ... to the exo-loop of OXG-RCBH. The coordinates and structure factors have been deposited in the Protein Data Bank (PDB) (accession code 3A0F). The structure of...

Ngày tải lên : 23/03/2014, 05:22

7
361
0

Báo cáo khoa học: The crystal structure of the ring-hydroxylating dioxygenase from Sphingomonas CHY-1 pot

... domain with the active site of the enzyme on one side and the Rieske center on the other side of the sheet (Fig. 3). Covering one side of the sheet are two Fig. 2. Crystal structure of PhnI. Ribbon ... following the sequence.) Together with the extended loop, which extends 20 A ˚ from the center of the funnel, they form the base of the b subunit (Fig. 3...

Ngày tải lên : 23/03/2014, 09:21

12
451
0

Báo cáo khoa học: The crystal structure of a hyperthermostable subfamily II isocitrate dehydrogenase from Thermotoga maritima pdf

... different domains of IDH were searched for separately because of different domain orienta- tions found in other IDH crystal structures. The rotation and the position of the dimer of the small domains, ... structure of the dimeric apo form of TmIDH at 2.2 A ˚ . The R-factor of the reﬁned model was 18.5% (R free 22.4%). The conformation of the TmIDH struct...

Ngày tải lên : 23/03/2014, 10:21

18
410
0

Báo cáo khoa học: The crystal structure of Thermoactinomyces vulgaris R-47 a-amylase II (TVA II) complexed with transglycosylated product potx

... 5C). The positions of the maltose unit, Glc )1and)2, are almost the same in the two enzymes. However, the position of Glc ) 3of4 2 -P2 is completely different from that of acarbose. In the case of ... reaction. 4 2 -P2 binding The complexed structure enables a detailed analysis of the interactions of the active site with 4 2 -P2. To facilitate description of...

Ngày tải lên : 23/03/2014, 12:20

9
361
0

Báo cáo khoa học: The crystal structure of pyruvate decarboxylase from Kluyveromyces lactis Implications for the substrate activation mechanism of this enzyme ppt

... omitted in the ﬁnal model, and the position of the residues adjacent to the loop are labeled. The orientation of the subunit is the same as that of subunit B in Fig. 1. Crystal structure of pyruvate ... FEBS 4203 Structure of the active site The general architecture of the active site of KlPDC corresponds to that of other ThDP-dependent enzymes. Fig...

Ngày tải lên : 30/03/2014, 10:20

11
374
0