Báo cáo khoa học: Reannotation of hypothetical ORFs in plant pathogen Erwinia carotovora subsp atroseptica SCRI1043 pot

... Reannotation of hypothetical ORFs in plant pathogen Erwinia carotovora subsp. atroseptica SCRI1043 Ling-Ling Chen, Bin-Guang Ma and Na Gao Shandong Provincial Research Center for Bioinformatic ... training set. Using the final Fisher coeffi- cients and the criterion for deciding coding ⁄ noncoding, the hypothetical ORFs in Eca1043 were re-identified. A total of 49...

Ngày tải lên: 23/03/2014, 07:20

... shown that interactions between KCs and endotoxin comprise the initiating event lead- ing to hepatotoxicity in liver injury, including endotox- emia and ischemia ⁄ reperfusion injury [14]. In our studies, ... mediator of lethal sepsis, triggering the production of proinflammatory cytokines and liver injury [13]. Therefore, the present study aimed to elucidate the role of KCs in the...

Ngày tải lên: 14/02/2014, 18:20

... long-chain saturated fatty acids (SFAs) led to increased expression of proin- flammatory cytokines, inhibition of insulin signaling, induction of endoplasmic reticulum (ER) stress, and promotion of ... elevations in the expression of activating transcription factor 4 (ATF4) and of CCAAT⁄ enhancer-binding protein homologous protein (CHOP) proteins downstream of eIF2a were observ...

Ngày tải lên: 14/02/2014, 22:20

... role in skin wound healing. After a skin injury, PPARb expression is rap- idly elevated in the epidermis at the wound edges; dele- tion of a single PPARb allele results in delayed wound healing ... cultured human keratinocytes [14]. In this study, we examined the interaction between CerK and PPARb, and its role in regulating keratino- cyte survival. We report that in a mouse ker...

Ngày tải lên: 18/02/2014, 18:20

... these three arginines in TClpB. By combining an arginine mutation with the WalkerA mutation in the other AAA+ module, we tested the roles of the arginines in ATP binding and hydrolysis in each module. ... of the hexameric form, but not for the ATP-induced motion of the middle domain. Results The conserved arginines are not involved in nucleotide binding To examine the roles o...

Ngày tải lên: 06/03/2014, 00:20

... determine the role of specific amino acids in protein–protein interactions. For instance, selective carbamylation of the a-amino group of the tissue inhibitor of metalloproteinases-2 NH 2 -ter- minal ... for binding to the I domain of a 2 integrins [24]. Similarly, members of the ‘lysine–threo- nine–serine (KTS)–disintegrin’ family contain the consensus KTS sequence, rather than...

Ngày tải lên: 07/03/2014, 06:20

... enabling this work we trained a multitude of instances of the same phrase-based SMT sys- tem on 30 distinct combinations of language-pair and domain, each with fourteen distinct training sets of increasing ... point but lies within the range of the set of initial points. However, it does give a measure of the closeness of the curve fit using only the initial points with the gol...

Ngày tải lên: 07/03/2014, 18:20

... with ADP indicated in red. The helix-turn-helix (HTH)-containing DNA binding domain of DnaA is in green and the winged helix (WH)-containing domain of Orc1 ⁄ Cdc6 is in dark blue. N. P. Robinson ... the origin of replica- tion in Pyrococcus, providing the first experimental proof of a localized origin of replication in the archaea [52]. Interestingly, in a situation remin...

Ngày tải lên: 07/03/2014, 21:20

... handling these kind of linguistic constraints using integer pro- gramming approaches (Riedel et al., 2006; Bha- rati et al., 2008). In these approaches dependency parsing is formulated as solving ... in any case (Bharati et al., 2009). For example, even in case of coordination, coordinating con- junction is the head and conjuncts are children of the coordinating conjunction. T...

Ngày tải lên: 07/03/2014, 22:20

... being an integrated information unit, always has special syntactic structure. This kind of informa- tion is considered quite important to sentence relevance. How to incorporate this kind of infor- mation ... term distribution in sentence, the necessary of incorporating term dependence into sentence retrieval is clear. Two kinds of dependence can be considered in the service...

Ngày tải lên: 08/03/2014, 02:21