Báo cáo khoa học: The C-terminus of viral vascular endothelial growth factor-E partially blocks binding to VEGF receptor-1 docx

... pathway (A, C) and the direct fusion of the viral envelope to the plasma membrane (B) lead to the retrograde transport along microtubules using the cytoplasmic the dynein motor. Viral capsid proteins ... directed to the sites of replication, production and assembly of the new viral proteins (D) such as the nucleus or the viral factories. The newly ass...

Ngày tải lên: 14/03/2014, 22:20

... at the basal position within the Pterygota. The hemocy- anins from Zygentoma (TdoHc1+ LsaHc1) form the sistergroup of the pterygote proteins. ScuHc1+ FcaHc1 (Collembola) is basal to the ectognathan subunits, ... hemocyanin in the stonefly Perla marginata (Plecoptera) and in the firebrat Thermobia domestica (Zygentoma). We used RT-PCR and RACE experiments to study the pre...

Ngày tải lên: 18/02/2014, 08:20

... predomi- nates is thought to be determined by a number of fac- tors, including the rate of unfolding, the amino acid sequence of the protein, the experimental conditions and the nature of the intermediate ... decrease in the amount of precipitation in the presence of high concentrations of Arg-HCl in the absence of the chaperone precluded analysis of t...

Ngày tải lên: 18/02/2014, 16:20

... linker histones H1 and H5. Indeed, there is evidence that the tails of these histones follow the path of the linker DNA [5]. They are crosslinked first to each other first and subse- quently to the core ... in which the presence of linker his- tone is questionable. Furthermore, the presence of all oligomers, with dimers up to the half the size of the original s...

Ngày tải lên: 18/02/2014, 18:20

... (s). The relative fraction of bound 32 P-labeled DNA (R) is the ratio of the fraction of bound 32 P-labeled DNA in the presence of the competitor DNA (cpm bound ⁄ cpm total ) to the fraction of ... either M.SssI or M.HhaI. The extent of the methylation is almost independent of the position of the damaged guanine residue X + . Discussion The goal of ou...

Ngày tải lên: 19/02/2014, 00:20

... at the cell surface. Treatment with SU5402 was able to at least partially restore trafficking of the K650M mutant receptor to the cell surface and its sub- sequent endocytosis. Retention of the ... apparently decreased the affinity of the anti-FGFR3 serum for the receptor, so that a higher amount of total protein had to be loaded onto the gel in order to obtain...

Ngày tải lên: 19/02/2014, 00:20

... appears to be linked to the attraction of the RNase to a membrane, as evidenced by the RNase negative EIE max values. As a measure of the RNase cytotoxicity we used the reciprocal of the IC 50 parameter. ... requirement for the cytotoxic action of all cytotoxic RNases tested [5]. Moreover, when the effects of cytotoxic RNases on cellular RNA were studied, cytos...

Ngày tải lên: 19/02/2014, 06:20

... are currently searching for the structures of the recombination inter- mediates that lead to cell death. We are also investigating the role of the MMR system in the cytotoxicity of 5-fluorouracil (FU), ... fusion with the membrane of intra-endosomal vesicles contained within MVBs, thereby releasing the nucleocapsid into the lumen of these vesi- cles. Then, the cap...

Ngày tải lên: 19/02/2014, 07:20

... 235 [9]. Of theses residues, only Arg213 is in the vicinity of the active site of RTA. In order to establish the role of arginyl residues around the active site of RTA in the binding of rRNA, ... red. C 1 of the hexanucleotide is at the bottom left and the target adenine is at the top of each model. The sidechains of RTA are shown in blue. (A) Model 1...

Ngày tải lên: 19/02/2014, 12:20

... three-dimensional model of the Asterias lysozyme i. These figures were generated with the help of the SWISS - PDBVIEWER software. (A) ApartoftheputativestructureoftheAsterias lysozyme, from residues L9 to L50 ... this plot and the corresponding part of the HCA plot of the Asterias lysozyme. The same overlap is obtained when comparing the human lysozyme and/or the ch...

Ngày tải lên: 19/02/2014, 12:20