Báo cáo khoa học: A novel factor XI missense mutation (Val37

Báo cáo khoa học: A novel factor XI missense mutation (Val371Ile) in the activation loop is responsible for a case of mild type II factor XI deﬁciency doc

... novel factor XI missense mutation (Val371Ile) in the activation loop is responsible for a case of mild type II factor XI deﬁciency Cristina Bozzao 1 *, Valeria Rimoldi 1 *, Rosanna Asselta 1 , ... Haematolog- ica 89, 1332–1340. 42 Naito K & Fujikawa K (1991) Activation of human blood coagulation factor XI independent of factor XII....

Ngày tải lên : 23/03/2014, 07:20

11
563
0

Báo cáo khoa học: Insights into substrate and product trafﬁc in the Drosophila melanogaster acetylcholinesterase active site gorge by enlarging a back channel ppt

... efﬁciency of the alternative route compared to the main entrance, or to a partial overlap of the side chain of propidium and a atoxin with the active site as it may span into the gorge. Experimental ... obtained by assuming that mutations did not affect binding of substrate at the peripheral site (K p ), the rate constant for deacetylation (k 3 ) and the accelerat...

Ngày tải lên : 07/03/2014, 05:20

6
524
0

Tài liệu Báo cáo khoa học: Nop53p, an essential nucleolar protein that interacts with Nop17p and Nip7p, is required for pre-rRNA processing in Saccharomyces cerevisiae pdf

... 5¢-GCCGCTTCACTCGCCGTTACTAAGGC-3¢ [28] anti-U3 5¢-ATGGGGCTCATCAACCAAGTTGG-3¢ [49] anti-U14 5¢-CTCAGACATCCTAGGAAGG-3¢ [28] anti-snR11 5¢-GACGAATCGTGACTCTG-3¢ [20] anti-snR37 5¢-GATAGTATTAACCACTACTG-3¢ ... cerevisiae Daniela C. Granato 1 , Fernando A. Gonzales 1 , Juliana S. Luz 1 , Fla ´ via Cassiola 2 , Glaucia M. Machado-Santelli 2 and Carla C. Oliveira 1 1 Department of Biochemistry, Chem...

Ngày tải lên : 20/02/2014, 01:20

14
505
0

Báo cáo khoa học: Relationship between functional activity and protein stability in the presence of all classes of stabilizing osmolytes ppt

... published elsewhere. We have therefore measured the thermodynamic parameters of RNase -A in the presence of these amino acids and amino acid derivatives, and values of DG D °, measured in triplicate, ... amino acids and amino acid derivatives) the slope is nearly 0. This is an expected result, as there is no perturbation of the denaturation equilibrium and, hence, t...

Ngày tải lên : 07/03/2014, 00:20

9
547
0

Báo cáo khoa học: "COMMON TOPICS AND COHERENT SITUATIONS: INTERPRETING ELLIPSIS IN THE CONTEXT OF DISCOURSE INFERENCE" ppt

... this aspect was crucial for handling the gapping data, since the infelicity of gapping in non-parallel constructions hinged on there no longer being a propositional representation available as ... whether the form leaves behind an empty constituent in the syntax, and (2) whether the form is anaphoric in the semantics. It is proposed that these features interact...

Ngày tải lên : 08/03/2014, 07:20

8
511
0

Báo cáo khoa học: Calpain 1–titin interactions concentrate calpain 1 in the Z-band edges and in the N2-line region within the skeletal myoﬁbril doc

... or by the RtC 1A Ab, contains calpain and the titin recombinant fragment in the pellet, as revealed by Western blot using RtC 1A Ab (Fig. 7A) and RZ 9a Ab (Fig. 7B). In an ELISA assay (data not shown), ... helical content of the epitope [9]. The localization of calpain 1 in the periphery of the Z-line is based on its colocalization with myotilin, an alpha-actin...

Ngày tải lên : 23/03/2014, 13:20

13
467
0

Báo cáo khoa học: "Event-coreference across Multiple, Multi-lingual Sources in the Mumis Project" doc

... for automatic indexing and retrieving of image and video frag- ments on the basis of analysis of their visual features. Many research projects therefore have ex- plored the use of collateral ... textual descriptions of the multimedia information for automatic tasks such as indexing, classifying, or understanding. The Multimedia Indexing and Searching En- vironment (MUM...

Ngày tải lên : 24/03/2014, 03:20

4
314
0

Tài liệu Báo cáo khoa học: Two novel variants of human medium chain acyl-CoA dehydrogenase (MCAD) K364R, a folding mutation, and R256T, a catalytic-site mutation resulting in a well-folded but totally inactive protein pptx

... mutation, this could either mask or enhance the clinical manifestation of the disease [6,26]. Although the individuals with this mutation have remained asymptomatic, the analogous mutations in glutaryl-CoA ... individual depending on the functional overlap of VLCAD, LCAD, MCAD and SCAD, the efﬁciency of the chaperonin-aided folding, the efﬁ- ciency of the detoxi...

Ngày tải lên : 20/02/2014, 02:21

9
533
0

Tài liệu Báo cáo khoa học: PC1⁄3, PC2 and PC5⁄6A are targeted to dense core secretory granules by a common mechanism doc

... triad of amino acids aspartic acid, histidine and serine, and a stabilizing P-domain involved in the binding of Ca 2+ [1]. The C-terminal domains of the PC enzymes exhibit the least amount of homology ... Likewise, a protein domain in the C-terminal tail of PC2 is capable of redirecting heterologous proteins to secretory granules [5,6]. This sorting activity i...

Ngày tải lên : 18/02/2014, 16:20

9
600
0

Tài liệu Báo cáo khoa học: Staphylococcal enterotoxin C1-induced pyrogenic cytokine production in human peripheral blood mononuclear cells is mediated by NADPH oxidase and nuclear factor-kappa B doc

... system. The area under the curve was calculated to obtain total chemiluminescence. Statistical analysis The animals were maintained at an ambient temperature of 22 °C for at least 90 min to obtain the ... [2], and ingestion of staphylococcal enterotoxins causes emesis and diarrhea [4]. Staphylococcus aureus is also an important microorganism of bovine, ovine and caprine mast...

Ngày tải lên : 19/02/2014, 00:20

13
465
0