Báo cáo khoa học: Peroxisome proliferator-activated receptor a–retinoid X receptor agonists induce beta-cell protection against palmitate toxicity doc

... c rings. Most of the examples selected exhibit additional central pro- trusions. (D) A gallery of c rings observed from the crystalline arrangement. Examples selected exhibit additional central ... c rings. Most of the examples selected exhibit additional central protru- sions. (D) A gallery of c rings observed from the crystalline arrangement. Examples selected exhibit additional central ......

Ngày tải lên: 07/03/2014, 21:20

... rabbits experimentally infested with females of Haemaphysalis longicornis (Ixodoidea: Ixodidae). Natl Inst Anim Health 18, 27–38. 19 Fujisaki K, Kawazu S & Kamio T (1994) The taxon- omy of ... its parthenogenetic and bisexual popula- tions (Ixodoidea, Ixodidae). J Parasitol 54, 1197–1213. 21 Liao DI & Remington SJ (1990) Structure of wheat ser- ine carboxypeptidase II at 3.5 A ˚ resol...

Ngày tải lên: 16/03/2014, 10:20

... Peroxisome proliferator-activated receptor a plays a vital role in inducing a detoxification system against plant compounds with crosstalk with other xenobiotic nuclear receptors Kiyoto ... (1998) Peroxisome proliferator activated receptor- a expression in human liver. Mol Pharmacol 53, 14–22. 3 Motojima K (2004) 17b-hydroxysteroid dehydrogenase type 11 is a major peroxisome prol...

Ngày tải lên: 16/03/2014, 14:20

... with 500 lm palmitate (acute toxic- ity) and for 8 days at 250 lm (chronic toxicity) . Islet endocrine nonbeta-cells exhibited lower suscep- tibility to palmitate toxicity: cytotoxicity was 9 ... et al. Beta-cell protection against palmitate toxicity FEBS Journal 274 (2007) 6094–6105 ª 2007 The Authors Journal compilation ª 2007 FEBS 6105 Peroxisome proliferator-activated...

Ngày tải lên: 23/03/2014, 07:20

... most of these genes, except for survivin (to approximately 200%), PKCa (to approximately 60%), PKCg (to approximately 40%), PKCl (to approximately 40%) and PKCf (to approximately 160%). In addition, ... E2A )/) (clone 1) were plotted on linear histograms as relative cell number (y axis) against red fluorescence intensity (x axis). The percentages of the various cell-cycle phases (sub-G 1 ,G...

Ngày tải lên: 16/03/2014, 04:20

... estimate large phylogenies by maximum likelihood. Syst Biol 52, 696–704. 33 Maestro O, Cruz J, Pascual N, Martı ´ n D & Belle ´ sX (2005) Differential expression of two RXR ⁄ ultraspiracle isoforms ... incorporated into the oocyte through a receptor- mediated endocytic pathway [3], and a key element in the whole process is the vitellogenin receptor (VgR). Quite unexpectedly, reported V...

Ngày tải lên: 16/03/2014, 14:20

... Janssen O & Saftig P (2007) ADAM10 regulates FasL cell surface expression and modulates FasL-induced cytotoxicity and activation- induced cell death. Cell Death Differ 14, 1040–1049. 58 Martin ... ADAM10 [22]. The catalytical domain of ADAM10 contains a typical zinc-binding consensus motif (HEXGHXX GXXHD; Fig. 1) and the point mutation E384A, which compromises this motif, leads to a subst...

Ngày tải lên: 16/02/2014, 09:20

... CXXC domain of MLL1 may play a role in targeting MLL1 to active genes. To 1143 1215 3790 3762 3770 MLL1 CXXC 1LLMniamod SET domain WDR5 MLL1 Win motif 2838 2879 CBP-KIX domain SET TAD CXXC 1- -3969 3969 Win MLL1 ... domain E666 E665 K291 R294 C-Myb CBP-KIX domain MLL1-TAD domain Ternary complex α3 α1 α2 α1 α3 α2 E666 E665 K291 R294 C-Myb CBP-KIX domain Binary complex CBA Fig. 2. The CXXC...

Ngày tải lên: 16/02/2014, 14:20

... folding; thiol–disulfide exchange Correspondence L. W. Ruddock, University of Oulu, Department of Biochemistry, PO Box 3000, University of Oulu, Oulu 90014, Finland Fax: +358 8 5531141 Tel: +358 ... NAD(P)H oxidase [20], the shedding of human thyrotropin receptor ectodomain [21], the aggregation of Cu ⁄ Zn superoxide dismutase in motor neurons [22], the operation of the vitamin K cycle [23],...

Ngày tải lên: 16/02/2014, 14:20

... of the triple mutant Y74W* is expected to result in solvent exposure of the buried Trp74 residue. Figure 4 summa- rizes the dependence of the emission maxima (k max )on protein concentration for ... the Michaelis– Menten equation (Eqn 1) as follows: v ¼ V max S½=K m þ S½ ð1Þ where v and V max are the initial velocity and the maximum velocity, respectively, K m is the Michaelis constant, ......

Ngày tải lên: 18/02/2014, 11:20