Báo cáo khoa học: Structural properties of semenogelin I docx

... Italy; 5 Dipartimento di Scienza degli Alimenti, Universita ` degli Studi di Napoli ‘Federico II’, Italy; 6 Istituto Internazionale di Genetica e Biofisica, CNR, Napoli, Italy We have investigated the ... University Napoli, Italy; 3 Centro di Ricerca Interdipartimentale di Scienze Computazionali e Biotecnologiche, Napoli, Italy; 4 Istituto di Scienze dell’Alimentazione, CNR, Roma, Italy; 5 Dip...

Ngày tải lên: 07/03/2014, 14:20

... rota- tion of the lower b 3 leg already accompanies extension, bringing the activating residues into contact with other residues in the a IIb subunit. In addition, some caution should be exerted in ... Mattia Rocco 2 1 Nanobiotecnologie, Istituto Nazionale per la Ricerca sul Cancro (IST), Genova, Italy 2 Biopolimeri e Proteomica, IST, Genova, Italy Introduction Integrins are heterodimeric t...

Ngày tải lên: 18/02/2014, 04:20

... C-pep- tide is involved in the disaggregation of insulin, increas- ing insulin bioavailability by monomerization [12,13]. C-peptide itself has been shown to adopt unordered structures in aqueous ... presence Fig. 1. Oligomer formation of proinsulin C-peptide is affected by metals and insulin. Prosinsulin C-peptide oligomer formation as a function of time (A). C-peptide was incu- bated f...

Ngày tải lên: 18/02/2014, 04:20

... substi- tutions at these sites do not significantly impair enzyme activity [28]. Interestingly, the bulky Trp residue is found at this position in the sequence of TIM from Giardia lamblia (GlTIM) ... labile. Discussion Effects of the Y74W mutation Residue 74, which lies at the dimer interface of PfTIM, appears to be important in promoting subunit dissocia- tion [27] and also in maintaini...

Ngày tải lên: 18/02/2014, 11:20

... electrostatic interaction, we analyzed in vitro the reversibility of such interaction. Cytosolic A i ii iii BC Fig. 3. Membrane binding properties of K-Ras. (A) Membrane fractions of CHO-K1 cells ... membranes. Inhibition of synthesis of polyphosphoinositides (poly PIs) in live cells, by depletion of cellular ATP, resulted in signifi- cant accumulation of K-Ras in a perinucle...

Ngày tải lên: 19/02/2014, 00:20

... Castiglione Morelli MA, Strazzullo G, Fucile P, Gautel M & Motta A (2001) Kinase recogni- tion by calmodulin: modeling the interaction with the autoinhibitory region of human cardiac titin kinase. J ... (1991) Triple- resonance multidimensional NMR study of calmodulin complexed with the binding domain of skeletal muscle myosin light-chain kinase: indication of a conforma- tional c...

Ngày tải lên: 19/02/2014, 17:20

... modulatory inhibitors are often colocalized with their targets. Cyst- atin F could be a candidate for modulating the activity of cathepsin H; in vitro inhibition is tight enough to impair its activity ... prolonged incubation at dithiotrei- tol concentrations as high as 100 mm, and the K i value for the inhibition of papain (K i ¼ 1.4 nm) was similar to that reported for inhibition at...

Ngày tải lên: 19/02/2014, 17:20

... sequence tic is frequently encountered followed by al, ize, or ide to form tical, ticism, ticize, or ticide, as in elliptical, asepticism, didacticism, ascepticize, romanti- cize, and infanticide. ... utilitarian evaluation of their validity can be made after the syntactic and phonetic implica- tions of the defined affixes have been investigated. The definitions for affixes given in...

Ngày tải lên: 19/02/2014, 19:20

... Rapid and sensitive method for the quantitation of microgram quantities of protein util- izing the principle of protein-dye binding. Anal Biochem 72, 248–254. 33 Laemmli UK (1970) Cleavage of structural ... of a chitinase from the pathogenic fungus Coccidioides immitis. Protein Sci 29, 544–551. 29 Watanabe T, Kobori K, Miyashita K, Fujii T, Sakai H, Uchida M & Tanaka H (1993)...

Ngày tải lên: 20/02/2014, 01:20

... Italy; 3 Dipartimento di Biochimica, Biofisica e Chimica delle Macromolecole, Universita ` degli Studi di Trieste, Italy The transcription factor v-Myb is a potent inducer of myeloid leukemias, and its cellular ... Norway. Fax:+4722854443,Tel.:+4722857346, E-mail: o.s.gabrielsen@biokjemi.uio.no Abbreviations: DBD, DNA-binding domain; MRE, Myb recognition element; NRD, negative regulatory dom...

Ngày tải lên: 21/02/2014, 00:20