Báo cáo khoa học: Heavy metal ions inhibit molybdoenzyme activity by binding to the dithiolene moiety of molybdopterin in Escherichia coli pdf

... molybdate to molybdopterin generates the molybdenum cofactor, which can be inserted directly into molybdoenzymes binding the molybdopterin form of the molybdenum cofactor, or is further modified in bacteria ... mixture did not result in their insertion into MPT (data not shown). In addition, we tested the insertion of metal ions into MPT-containing hSO. None of...

Ngày tải lên: 23/03/2014, 06:20

... cycles in such a combination do not touch each other). The value (the sign) of a cycle is the product of the values (the signs) of its steps. The sign o f the magnitude of a Ôminus combined autoinfluence ... rise to a negative in the characteristic equation (a positive autoinfluence). The absolute magnitude of a combined autoinfluence path is the product of al...

Ngày tải lên: 19/02/2014, 16:20

... hour of binding, regardless of the input titer (Fig. 1B). FPGN-containing peptides facilitate the uptake of adenovirus into CD40-expressing cells To test the ability of CD40 -binding peptides in ... Infection of cells by AdV-GFP complexed to the AAAA2-KBP peptide was at levels similar to those obtained in the absence of peptide, indicating that the FPGN...

Ngày tải lên: 20/02/2014, 11:20

... phospha- tidylinositol 3-kinase (PI3K), Akt and glycogen synthase kinase 3 (GSK3). Together, our results support a role of P2X7 receptors in the regulation of neuritogenesis and in the fine control of the ... receptors in the maintenance of neuroblastoma cells in a nondifferentiated state, and point to P2X7 receptor antagonists as future potential therapeutic agents...

Ngày tải lên: 07/03/2014, 02:20

... evaluation, the 5W task. The 5W task seeks to summarize the informa- tion in a natural language sentence by distilling it into the answers to the 5W questions: Who, What, When, Where and Why. To solve ... ambiguity. In the case of multiple top-level predicates, any of the top-level predicates may be chosen. In the case of passive verbs, the Who is th...

Ngày tải lên: 08/03/2014, 00:20

... value), the biomass concentration is determined only by the buffering capacity of the in owing medium (BC R , defined as the amount of acid or base required to change the pH of 1 L of the medium in the ... examined. Both the cell surface area and volume increased with the increasing number of generations as determined by the number of bud scars. Our cal...

Ngày tải lên: 16/03/2014, 04:20

... unknown. The three amino acids G159, K160, and S161 are involved in binding of the triphosphate moiety of ATP or GTP [19,32]. The muta- tions G159A and K160A completely abolish the binding of ATP ... This is in good agreement with the proposal that S161 is involved in the catalytic activity, in addition to its role in triphosphate binding. In the HPrK...

Ngày tải lên: 16/03/2014, 16:20

... the cells in the presence of DIF-1, we examined the effect of DIF-1 on glucose consumption by monitoring the glucose concen- tration in the incubation media (Fig. 3A). As expected, DIF-1 at the ... enzymes involved in glucose metabolism in 3T3-L1 fibroblasts To further investigate the mechanism of the action of DIF-1, we examined the effects of DIF-1 on...

Ngày tải lên: 23/03/2014, 09:20

... Mutations in the 23S ribosomal RNA in the vicinity of the double hook binding or in the b-hairpin of protein L22 were shown to bypass the elongation arrest [72]. The swing of protein L22 hairpin ... and the L22 double hook should trigger the swing of the entire b-hairpin tip, in a manner similar to that caused by TAO binding. As a result of the s...

Ngày tải lên: 23/03/2014, 17:22

... is the most important DNA–protein complex that contains the candidate transcriptional factors induced by TPA. Taken together, by examining the pattern of SII we suggest that the in vitro DNA -binding ... for in vitro DNA -binding activity of the candidate transcriptional factors The critical role of the overlapping EGR-1/SP-1 region was further investigated by...

Ngày tải lên: 29/03/2014, 08:20