Báo cáo khoa học: A decade of Cdc14 – a personal perspective Delivered on 9 July 2007 at the 32nd FEBS Congress in Vienna, Austria pdf
... the metaphase–anaphase transition, Separ- ase, a protease that triggers the separation of sister chromatids at the metaphase–anaphase transition [46] also regulates cyclin degradation and hence ... 2008 FEBS THE IUBMB LECTURE A decade of Cdc14 – a personal perspective Delivered on 9 July 2007 at the 32nd FEBS Congress in Vienna, Austr...
Ngày tải lên: 23/03/2014, 06:20
... a determinant of planar cell polarity through the nonca- nonical Wnt signalling pathway, accumulates in the cytoplasm instead of translocating to polarized mem- brane domains [48]. Accumulating evidence ... revealed another important PtdIns3P effector in endosomal tethering and fusion, namely EEA1, a protein that contains a Rab5 binding domain and a FYVE domain at its C-...
Ngày tải lên: 06/03/2014, 01:23
... identity) of these domains in relation to U2AF 35 is indicated. Table 2. Domain organization of U2AF 35 and U2AF 35 -related proteins. Domains are annotated as described in [18]. Zn, zinc binding; ... Identification, purifica- tion, and biochemical characterization of U2 small nuclear ribonucleoprotein auxiliary factor. Proc Natl Acad Sci USA 86, 92 4 3 9 247. 8 Zamore PD, Patton JG...
Ngày tải lên: 23/03/2014, 10:20
Báo cáo khoa học: Mitochondrial calcium signalling in cell death Delivered on 1 July 2004 at the 29th FEBS Congress in Warsaw pptx
... regulation of aerobic metabolism and the induction of cell death, and new insight into the regulatory mechanisms operating in vivo. Abbreviations AGC, aspartate ⁄ glutamate metabolite carrier; ... which the energization state (and thus the capacity to accu- mulate Ca 2+ ) was shown to in uence the spatio-tem- poral pattern of the typical propagating Ca 2+ waves induced by...
Ngày tải lên: 30/03/2014, 20:20
Tài liệu Báo cáo khoa học: Transactivation properties of c-Myb are critically dependent on two SUMO-1 acceptor sites that are conjugated in a PIASy enhanced manner pptx
... reduction in sumoylation and increase in transcriptional activation. Enhancing sumoy- lation by contransfection of PIASy had a negative effect on both Myb-induced and basal level reporter activation. Furthermore, ... subnuclear fractionation, which indicates that sumoylation might be involved in modulating the protein–protein interactions of c-Myb. Materials and methods Plasmid...
Ngày tải lên: 21/02/2014, 00:20
Báo cáo khoa học: Pharmacology of vascular endothelium Delivered on 27 June 2004 at the 29th FEBS Congress in Warsaw pptx
... should have been. At the time, Bk was per- ceived as a mediator of pain and in ammation respon- sible for paralytic vasodilatation in the course of acute pancreatitis. The reasoning was as follows: ... PGI 2 - dependent mechanism [ 79] . In cultured bovine aortic endothelial cells lipophylic statins, i.e. atorvastatin, simvastatin and lovastatin (but not a hydrophilic pra...
Ngày tải lên: 07/03/2014, 21:20
Báo cáo khoa học: Hematopoietic differentiation from human ESCs as a model for developmental studies and future clinical translations Invited review following the FEBS Anniversary Prize received on 5 July 2009 at the 34th FEBS Congress in Prague docx
... 460, 90 9 9 13. 89 Hong H, Takahashi K, Ichisaka T, Aoi T, Kanagawa O, Nakagawa M, Okita K & Yamanaka S (20 09) Suppression of induced pluripotent stem cell generation by the p53–p21 pathway. Nature ... Following trans- plantation and discontinuation of anti-retroviral ther- apy, no HIV-1 virus was detected in the patient over a 20-month period [22,23]. A combination of...
Ngày tải lên: 22/03/2014, 17:20
Báo cáo khoa học: Wisely chosen paths – regulation of rRNA synthesis Delivered on 30 June 2010 at the 35th FEBS Congress in Gothenburg, Sweden potx
... factor-depen- dent regulation of rDNA transcription [11]. Acetylation is another post-translational modifica- tion that regulates the activity of UBF and SL1. Acet- ylation of TAF I 68 by the the ... molecular path- ways that transmit information on the growth state of a cell population to the Pol I transcription apparatus represents a challenging and rewarding subject o...
Ngày tải lên: 29/03/2014, 21:20
Báo cáo khoa học: The yeast stress response Role of the Yap family of b-ZIP transcription factors The PABMB Lecture delivered on 30 June 2004 at the 29th FEBS Congress in Warsaw potx
... related yeast Kluveromyces lactis contain a unique transcription activation domain N-terminal to the DBD [4,5]. The HSF is a pre-existing transcription activator that binds to an array of a 5-bp ... subcellular localization. Indeed, Kuge et al. [14] demonstrated that Yap1 nuc- lear retention is mediated by the cysteine-rich domain (CRD) located at the C-terminus of the p...
Ngày tải lên: 30/03/2014, 16:20
Tài liệu Báo cáo khoa học: Crystal structure of importin-a bound to a peptide bearing the nuclear localisation signal from chloride intracellular channel protein 4 ppt
... importin -a nuclear import pathway, provided that CLIC4 can undergo a conforma- tional rearrangement that exposes the NLS in an extended conformation. Database Structural data are available in the ... S-nitrosylation of CLIC4 has been found to induce a conformational change which destabilizes the native conformation. Such a destabilization may facilitate the interaction b...
Ngày tải lên: 14/02/2014, 19:20