Báo cáo khoa học: Mouse RS21-C6 is a mammalian 2¢-deoxycytidine 5¢-triphosphate pyrophosphohydrolase that prefers 5-iodocytosine pdf

... methylation. Proc Natl Acad Sci USA 95, 8727–8732. 37 Matsumoto M, Hatakeyama S, Oyamada K, Oda Y, Nishimura T & Nakayama KI (2005) Large-scale analy- sis of the human ubiquitin-related proteome. ... 37965– 37973. A mammalian dCTPase that prefers 5-iodocytosine M. Nonaka et al. 1666 FEBS Journal 276 (2009) 1654–1666 ª 2009 The Authors Journal compilation ª 2009 FEBS Mouse RS2...

Ngày tải lên: 23/03/2014, 06:20

... in histological material is a valuable component of conventional histopathologi- cal analysis and may be of major prognostic import- ance [56]. Proliferation in immunohistochemical sections can ... antibody on formalin-fixed and paraffin-embedded tissues (Fig. 9). Antibodies against PCNA and Cdc45 stained malignant cells in a compar- able manner, e.g. on invasive-lobular mamma carci- noma...

Ngày tải lên: 19/02/2014, 00:20

... substrate for caspase 1; Ac-IETD-AMC is a substrate for caspase 8 and 10; Ac-LEHD-AMC is a substrate for caspases 2, 4, 5 and 9. Ac-DVPD-AMC, Ac-DPSD-AMC and Ac-ESQD-AMC are tetra peptide substrates representing ... follows: caspase 1, WEHD-AMC; caspase 2, VDVAD- AMC; caspase 3, DEVD-AMC; caspase 4, WEHD-AMC; caspase 5, WEHD-AMC, caspase 6, VEID-AMC; caspase 7, DEVD-AMC; ca- spase 8,...

Ngày tải lên: 19/02/2014, 13:20

... TAT ATG T Weak 3 aa 2 ⁄ 4 55067 TCA ATG C Weak 58 aa 3 33 39% 60929 60933 60939 GTA ATG C TGC ATG T TCC ATG G G Adequate Weak Adequate 13 aa 33 aa 31 aa 3¢ 76 49% – 4¢ 56 61% 61041 GGA ATG T Adequate ... [13]. Position Kozak consensus A GCC ATG G G Context ATG 1 330 AAG ATG A Adequate ATG 2 345 CTG ATG T Weak ATG 3 396 CCC ATG A Weak ATG 4 489 CTG ATG A Weak Hu-K4 A. Munck et al. 172...

Ngày tải lên: 19/02/2014, 17:20

... RNA helicase in translational repression is an RNA-mediated oligomer. Nucleic Acids Res 32, 1325– 1334. 5 Nakahata S, Kotani T, Mita K, Kawasaki T, Katsu Y, Nagahama Y & Yamashita M (2003) ... J & Wickens M (2004) Mammalian GLD–2 homologs are poly (A) polymerases. Proc Natl Acad Sci USA 101, 4407–4412. 18 Nakanishi T, Kubota H, Ishibashi N, Kumagai S, Watanabe H, Yamashita M, Kas...

Ngày tải lên: 07/03/2014, 05:20

... stromal cell-derived factor (SDF) -1alpha. Glycobiology 10, 21– 29. 34 Valenzuela-Fernandez A, Palanche T, Amara A, Mage- rus A, Altmeyer R, Delaunay T, Virelizier JL, Baleux F, Galzi JL & Arenzana-Seisdedos ... by T-cell-line-adapted HIV-1. Nature 382, 833–835. 7 Pablos JL, Amara A, Bouloc A, Santiago B, Caruz A, Galindo M, Delaunay T, Virelizier JL & Arenzana-Seis- dedos F (1...

Ngày tải lên: 16/03/2014, 18:20

... indicating a structural or a functional role for both pigments. A structural role was indicated in a Chl-less mutant that was reported to lack accumulation of the Cyt b 6 f complex in Clamydomonas ... phyty- lated chlorophyll precursor protochlorophyll a, and not chlorophyll a ,is associated with subunit b 6 . The data imply that a phytylated tetrapyrrol is an essential st...

Ngày tải lên: 23/03/2014, 07:20

... Bacterial IscU is a well folded and functional single domain protein Salvatore Adinolfi 1 , Francesca Rizzo 1 , Laura Masino 1 , Margie Nair 1 , Stephen R. Martin 1 , Annalisa Pastore 1 and ... here a structural characterization of this protein and demonstrate that E. coli IscU can be obtained as a recombinant well-folded protein. We demonstrate that our construct can function as...

Ngày tải lên: 23/03/2014, 12:20

... the last few years, a new concept has arisen, showing first that changes in po 2 level are not always sustained in tumours but that they can be transient, and second that intermittent hypoxia can ... radiation. Cancer Res 59, 3374–3378. 101 Kanaan A, Farahani R, Douglas RM, Lamanna JC & Haddad GG (2006) Effect of chronic continuous or intermittent hypoxia and reoxygenation on cere...

Ngày tải lên: 30/03/2014, 04:20

... consideration for important pro- teomics research. Acknowledgements We thank Barbara Baird, Ian Jardine, Neil Kelleher, Harold Scheraga and Klaas van Wyck for valuable discussions, and the General ... (229 kDa). Abbreviations BCA, bovine carbonic anhydrase; CAD, collisionally-activated dissociation; ECD, electron-capture dissociation; HAD, 3-hydroxyanthranilate- 3,4-dioxygenase; IRMPD, infrar...

Ngày tải lên: 18/02/2014, 16:20