Báo cáo khoa học: Reduced FAS transcription in clones of U937 cells that have acquired resistance to Fas-induced apoptosis ppt

... Journal compilation ª 2008 FEBS Reduced FAS transcription in clones of U937 cells that have acquired resistance to Fas- induced apoptosis Jeanette Blomberg, Kristina Ruuth, Maria Jacobsson, Andreas ... growth in progressively increasing con- centrations of stimulating Fas antibody [16]. To inves- tigate the molecular basis that underlies the resistance...

Ngày tải lên: 23/03/2014, 06:20

... ganglion cells might contribute to providing chromophore to melanopsin to maintain their light sensitivities. The expression and function of RPE65c in other cell types in the retina remains to be investigated. Earlier ... recycling of 11cRAL through a process involving multiple enzymes and retinoid-binding pro- teins between photoreceptors and retinal pigment epi- thelium (R...

Ngày tải lên: 14/02/2014, 14:20

... per- formed to obtain more insight into the regulation of Adfp expression in muscle cells. We studied the effect of palmitic acid and oleic acid on insulin signaling and the accumulation of TAG in relation ... both in HFD-P versus HFD-O versus HFD-S). As a result, the homeostasis model assessment of insulin resistance (HOMA-IR) index (cal- culated from fasting glucose and f...

Ngày tải lên: 06/03/2014, 09:22

... probabilities during a beginning -to- ending (left -to- right) decod- ing process, the succeeding context for the current word is either yet to be generated or incomplete in terms of n-grams. The ... P b (w m 1 ) to w m 1 by looking at the succeeding context according to P b (w m 1 ) = m  i=1 P (w i |w m i+1 ) ≈ m  i=1 P (w i |w i+n−1 i+1 ) (2) 3.1 Training For the convenience of...

Ngày tải lên: 07/03/2014, 22:20

... major domains for its adaptor function, the importin b binding (IBB) domain in its N-terminus and the C-terminal NLS- binding domain. In the absence of importin b,an auto-inhibiting part of the ... Triton X-100 ⁄ -NaCl ⁄ P i for 5 min. To stain the nuclei, the cells were incubated for 5 min at room tempera- ture in 1 lgÆmL )1 DAPI (4¢6¢-diamidino-2-phenylindole) stain solution....

Ngày tải lên: 15/03/2014, 11:20

... tion of results. 1 Introduction Over the past few years, a growing number of researchers have begun to look at some of the fundamental questions in linguistics in a new light, using new tools ... into subpanes that group related con- trols together. Figure 2 shows a stylised view of the interface, showing each of the main control panes. Access to interface fun...

Ngày tải lên: 23/03/2014, 19:20

... incompetent protein. Binding to CaM shifts this equilibrium to the bioactive competent protein. The region of the catalytic subdomain, where a single Cys residue C75 was introduced (instead of a Tyr) in the conserved ... strong too. This indicates that this segment in the protein behaves rather independently from the rest of the molecule. It is tempting to speculate that i...

Ngày tải lên: 07/03/2014, 15:20

... latent growth factors have already been reported. Insulin-like growth factors are inactive when bound to insulin-like growth factor-binding proteins. Transforming growth factor-b is produced ... found that single-chain HGF was inactive in the presence of serine protease inhibi- tors in a hepatocyte proliferation assay, whereas the two-chain form was active even in the presence...

Ngày tải lên: 15/03/2014, 11:20

... seems to result in the dissociation of a tightly bound damaged cofactor or adenine-lacking cobalamin [36,37]. To elucidate the molecular basis of the specificities of reactivating fac- tors in the ... considered models of the damaged cofactor (adenine-lacking cobalamin) and intact coenzyme (adenine-containing cobalamin), respectively. As shown in Fig. 3A, when the diol dehydr...

Ngày tải lên: 16/03/2014, 05:20

... Manning C, Akbarali Y et al. (2003) Responses to the proinflammatory cyto- kines interleukin-1 and tumor necrosis factor alpha in cells derived from rheumatoid synovium and other joint tissues involve ... therapeutics as well. Together with our previous reports of the role of ESE-1 as an inducer of nitric oxide syn- thase in endothelial cells and as a mediator of pro -in amma...

Ngày tải lên: 19/02/2014, 17:20