Báo cáo khoa học: Viral entry mechanisms: the increasing diversity of paramyxovirus entry doc

... greatly with the elucidation of the crystal structures of the prefusion form of the PIV5 F protein [89] and of the postulated postfusion forms of the NDV and hPIV3 F proteins [90–92]. Despite these ... Journal 276 (2009) 7217–7227 ª 2009 The Authors Journal compilation ª 2009 FEBS 7227 MINIREVIEW Viral entry mechanisms: the increasing diversity of paramy...

Ngày tải lên: 23/03/2014, 04:20

... the relationship of these two molecules is still largely unknown. The aim of the current study was to investigate the potential involvement of nucleolin ⁄ C23 in the antiapoptotic mechanism of Hsp70. ... the condensation and fragmentation of their nuclei. The percentage of apoptotic cells was calculated as the number of apoptotic cells divided by the total numb...

Ngày tải lên: 16/02/2014, 09:20

... understand the biological significance of the differ- ence in TnI–TnC interactions, we compared the ability of TnC to neutralize the inhibitory effects of the C-ter- minal fragments in the presence ... ATnI 1)128 exhibited a band near the origin and at the middle of the gel, respectively. The bands corresponding to the free rabbit or Akazara scallop TnC were found...

Ngày tải lên: 20/02/2014, 01:20

... returns true if the morph of the descendant of d e is the same as the morph of the descendant of d s , or if both descendants have canonical mentions with an exact string match; the 3 We remove ... parse trees. The set of nonterminal labels associated with each word is the set of labels of the nodes for which that word was the head. For example, in the lexi...

Ngày tải lên: 20/02/2014, 09:20

... to the magnesium binding site M3 [4]. Fig. 4. The influence of Mg 2+ on the kinetic properties of APase from E. coli. The influence of Mg 2+ on the kinetic properties of APase from E. coli inthepresenceofaZn 2+ to ... influence the equilibrium concentration of the subunits. Deviation from linearity in the dependence of the Mg 2+ ion concentration It has been determi...

Ngày tải lên: 21/02/2014, 00:20

... dimethylsulfoxide-facilitated entry of saporin into the cytosol. The LEX2 inhibition of cargo delivery to the late endosomes would thereby increase the pool of saporin available for passage from the early endosomes ... disrupt the integrity of endosome mem- branes [13,14]. Neither reagent generated comparable levels of cellular sensitization to AB toxins or to the is...

Ngày tải lên: 07/03/2014, 05:20

... regarding the role of the ClpB N-domain (which shares a common fold with the N-domain of ClpA) in substrate selection [15–17]. One difficulty in understanding the role of the N-domain of ClpA stems ... initiated through productive binding to the substrate via two elements in ClpA, one in the N-domain and the other in the pore of the ClpA hexamer. In the case of...

Ngày tải lên: 07/03/2014, 05:20

... taken to be the subject of the clause. This ap- plies to about half of all the instances where the function of the relative pronoun is ambiguous. 2. On the other hand, if the form of the sub- ... be made by the position of the verb because of the rule that in a subordinate clause the verb must normally come at the end. How, then, are we to deter- m...

Ngày tải lên: 07/03/2014, 18:20

... which the N-terminus of the OTR is replaced with the corresponding sequence of the V 1a R [10]. The role of the N-terminus has been addressed recently by alanine-scanning mutagenesis of the N-terminus ... maintaining the conformational switch of the V 1a R in the off-state. The unique ability of arginyl to fulfil this constraining function in the N-terminus...

Ngày tải lên: 07/03/2014, 21:20

... Treebank, http://www.ilc.cnr.it/EAGLES96/synlex/node23.html models from the parse tree, the system takes the part -of- speech tags as the observation sequences, and learns the structure of the model using the in- formation expressed by the syntactic tags. ... grammar information are considered. The left hand side of the figure shows the original structure of the s...

Ngày tải lên: 08/03/2014, 02:21