Báo cáo khoa học: Hepatocyte nuclear factor-4a interacts with other hepatocyte nuclear factors in regulating transthyretin gene expression pot

... Harvey RH (2000) Protein-arginine methyltransferase I, the predominant protein-arginine methyltransferase in cells, interacts with and is regulated by interleukin enhancer-binding factor 3. J Biol ... interacts with chromo-helicase DNA-binding domain protein 3 and with the adaptor ⁄ signaling protein receptor of activated kinase 1 in the nucleus. Among the identified proteins tha...

Ngày tải lên: 16/03/2014, 13:20

... (1995) Imidazoline ⁄ guanidinium binding domains on mono- amine oxidases ) relationship to subtypes of imidazo- line-binding proteins and tissue-specific interaction of imidazoline ligands with monoamine-oxidase-B. ... forms of monoamine oxidase, monoamine oxidase A and mono- amine oxidase B, have been associated with imidazoline-binding sites (type 2). Imidazoline ligands saturate the imi...

Ngày tải lên: 07/03/2014, 10:20

... carbohydrate-binding sites are indicated. Each B-chain domain is composed of three homologous subdomains a, b, c and linking k subdomain which joins the B-chain to the A-chain or the first B-chain domain ... combining overlapping RACE-clones and cDNA we obtained full-size transcripts of the mistletoe toxic lectin genes. Like other type 2 RIPs (such as ricin and abrin) [2], the mlp genes do n...

Ngày tải lên: 07/03/2014, 15:20

... pro- tein–protein interaction. In this study, Osh6p was demonstrated to bind a pool of phosphatidylinositol phosphates (PtdInsP) including PtdIns(4)P, PtdIns(5)P, PtdIns(3,4)P 2 and PtdIns(3,5)P 2 with ... staining in- creased, and finally punctate staining was almost lost with predominant vacuolar staining at 30 min. Com- pared with wildtype, no delay of FM4-64 transport was observe...

Ngày tải lên: 07/03/2014, 21:20

... together with a target model 300 comprising a set of rules defining which sets of semantic atoms are consistent. The decoding pro- cess proceeds as follows: 3.1 Training and decoding Training data ... Java-based tool, randomly selecting 75% of it for use in training and keeping the rest for testing. During the course of the project, we routinely logged speech inter- actions with the sys...

Ngày tải lên: 08/03/2014, 21:20

... Compar- ing linguistic features for modeling learning in com- puter tutoring. In Proceedings of the 2007 confer- ence on Artificial Intelligence in Education: Build- ing Technology Rich Learning Contexts ... B. Steinhauser, Gwendolyn E. Campbell, Elaine Farrow, and Charles B. Callaway. 2010a. Intelligent tutoring with natural language support in the Beetle II system. In Sustaining...

Ngày tải lên: 08/03/2014, 21:20

... of studies using novel diadenosine polyphosphate analogs, with an oxymethylene group replacing one or two bridging oxygen(s) in the polyphosphate chain. These have been tested as potential substrates ... Novel diadenosine polyphosphate analogs with oxymethylene bridges replacing oxygen in the polyphosphate chain Potential substrates and/or inhibitors of Ap 4 A hydrolases Andrzej ... m...

Ngày tải lên: 16/03/2014, 04:20

... sesame-induced mRNAs in the intestine revealed that PPARa plays a vital role in inducing various xenobiotic metabolizing enzymes in the mouse intestine and liver. A PPARa ligand alone could not induce ... the intestinal and liver proteins of mice fed with various plant seeds were examined by western blotting. As shown in Fig. 2, a low level expression of 17b-HSD11 was detected onl...

Ngày tải lên: 16/03/2014, 14:20

... nursing handover (red, up-pointing arrows), the beginning and end of the daily medical shift (green, down-pointing arrows), and periods of routine nursing observations (pink, shorter, up-pointing ... a significant increase in the number of MET calls around periods of nursing handover and routine nursing observation. In addi- tion, although MET calls occurred more frequently during the...

Ngày tải lên: 25/10/2012, 10:45

... is typically in the range 2–3 mm [26]. Finding experimental evidence that electrical cou- pling is the key ‘spring’ interlinking the Ca 2+ stores has involved repeating the decoupling experiment ... cells form networks in regions such as the myenteric plexus (i.e. ICC-MY) and intra- muscularly within the smooth muscle (i.e. ICC-IM), interconnecting with each other and with adjacent...

Ngày tải lên: 16/02/2014, 09:20