Báo cáo khoa học: Cas utilizes Nck2 to activate Cdc42 and regulate cell polarization during cell migration in response to wound healing docx

... Synergistic induction of matrix metalloproteinase 1 by interleukin-1alpha and oncostatin M in human chondrocytes involves signal transducer and activator of transcription and activator protein 1 transcription ... are the extracellular response kinase (ERK 1/2), the p38 and the Jun N-terminal kinase, and they activate factors that target multiple activator protein-1 (AP-1) and...

Ngày tải lên: 21/02/2014, 00:20

... P (2002) The C-terminal extension of glyceraldehyde-3-phosphate dehydrogenase subunit B acts as an autoinhibitory domain regulated by thioredoxins and nicotinamide adenine dinucleotide. J Biol ... and photoperiodism, including flower initiation, are regu- lated by light as a signal via phytochromes and ⁄ or other photoreceptors [1,2]. In cyanobacteria, resetting of the circadian rhythm...

Ngày tải lên: 16/03/2014, 04:20

... metabolic engineering strategies to optimize plant freezing toler- ance. We confirm that a significant improvement in freezing tolerance in plants involves multiple regulatory instances in sucrose ... how to engineer plant metabolism in order to improve freezing tolerance, one could suggest increasing the maximum activities of enzymes participating in sucrose cycling. Assuming t...

Ngày tải lên: 14/02/2014, 22:20

... lacking this lea- der sequence is directed into the endoplasmic reticulum membrane with the nucleotide-binding domain facing the cytosol. Remarkably, in both target- ing routes, the ATP-binding cassette ... (1992) Cytochromes c1 and b2 are sorted to the intermembrane space of yeast mitochon- dria by a stop-transfer mechanism. Cell 69, 809–822. 20 Stuart R (2002) Insertion of proteins...

Ngày tải lên: 18/02/2014, 16:20

... (Matsumoto and al., 1997) for texts in Japanese and OAK2 (Sekine, 2001) for texts in En- glish were used in linguistic pre-processing. EDR (EDR, 1996) was used to translate context vectors of ... fol- lowing a statistics-based metric. Next, context vec- tors related to source words are translated using a preliminary bilingual seed lexicon. Similarity vec- tors SIM S→T and SIM...

Ngày tải lên: 20/02/2014, 16:20

... lines (Fig. 2A). In order t o minimize cell handling prior to FACS analysis, no ®xation step was included. Avoiding cell ®xation and working on living cells eliminates potential artefacts linked with ... Tat peptide in HeLa cells was also monitored, as performed in previous studies [9]. Uptake of the short ¯uorescein-labeled Tat peptide took place in wt-CHO cells and in th...

Ngày tải lên: 21/02/2014, 03:20

... collected, washed in NaCl ⁄ P i and resuspended in annexin-binding buf- fer. Cells were collected, washed in NaCl ⁄ P i and resuspended in binding buffer containing a final concentration of 0.5 lgÆmL )1 annexin ... antiapop- totic effect of Bcl-2, leading to an increase in the apoptotic levels caused by MTX in resistant cells, and on the other hand, down-regulation of vimen...

Ngày tải lên: 07/03/2014, 16:20

... Computational Linguistics. Dan Klein and Christopher D. Manning. 2003. Fast exact inference with a factored model for natural language parsing. In Advances in Neural Informa- tion Processing Systems ... can be imputed using a discrimi- native approach to maximize the (joint or condi- tional) likelihood or the classification margin in the training data (taking or not taking into accou...

Ngày tải lên: 07/03/2014, 22:20

... of sequence-independent artefacts, most of which are attrib- utable to their ability to bind a number of heparin-binding proteins [28]. In our search for allele-speci®c inhibitors based on single- nucleotide ... RNA primers in vivo in eukaryotic cells does not necessarily involve RNase H; Dna2 helicase, helicase E, or Ku helicase, acting together with FEN1/RTH1 are also good and p...

Ngày tải lên: 08/03/2014, 10:20

... cytoplasmic signalling cascades through their ability to bind in a GTP- dependent manner various effector proteins and thus altering their localization, protein–protein interaction and activity. Mutations in ... may contribute to the repression of contact inhibition. Contact-mediated inhibition of cell migration and cell proliferation is co-ordinately regulated by integrin...

Ngày tải lên: 16/03/2014, 18:20