Báo cáo khoa học: Curcumin suppresses the dynamic instability of microtubules, activates the mitotic checkpoint and induces apoptosis in MCF-7 cells ppt

... 3437–3448 ª 2010 The Authors Journal compilation ª 2010 FEBS Curcumin suppresses the dynamic instability of microtubules, activates the mitotic checkpoint and induces apoptosis in MCF-7 cells Mithu ... with vinblastine in inhibiting MCF-7 cell proliferation. Curcumin affected the localization of the kinesin protein Eg5 Because curcumin produce...

Ngày tải lên: 23/03/2014, 03:20

... proteins they probably form part of the copper binding sites in this protein. Although there are four histidines in the C-terminal, another histidine is present at position 18, and given the folded ... with glycine alone was performed and no binding was observed. In our hands, as others [54], the most reproducible data was obtained from injections of the metal into a s...

Ngày tải lên: 19/02/2014, 06:20

... distribution of fabp10a and fabp10b transcripts in developing and adult zebrafish, evidence of the divergence of regula- tory elements in the promoters of the fabp10a and fabp10b genes compared with the ... shown in capital letters, with the coding sequences of each exon underlined and the deduced amino acid sequence indicated below. The nucleo- tide posit...

Ngày tải lên: 16/03/2014, 00:20

... it marks the beginning of a noun- phrase (NP). On the other hand, “Theater” has an IOB value of I-NP because it is inside a noun- phrase (Milan Theater) and is not at the beginning of that constituent. ... with the overall most similar pair and then respect the initial ordering of the cluster, aligning remaining sentences sequentially. Each sentence is aligned against...

Ngày tải lên: 31/03/2014, 01:20

... could participate in proton translocation or, in the case of E103, in the binding of the twin-arginine motif in the signal peptide. The absence of any translocation defects leads us to conclude that these ... synthesis with cleavable, N-ter- minal signal peptides that almost invariably contain an essential twin-arginine motif in the N-terminal domain [9,10]. They t...

Ngày tải lên: 19/02/2014, 17:20

... set- ting, or in one domain, is not necessarily preferable in another domain. Indeed, sometimes the domain can change the meaning of a phrase entirely. In a food related context, the Chinese ... (2011) extends the same notion of condition- ing on provenance (i.e., the origin of the text) by re- moving the separate mapping step, directly optimiz- ing the weight of...

Ngày tải lên: 19/02/2014, 19:20

... headword of the node. In the following, the units of PIQ are bits. Conclusion Among the feature types in the same structural position of the parsing tree, the predictive information quantity of lexical ... sequence containing the leaf nodes of the partial parsing tree rooted by the current node, representing the final objectives to be derived from the c...

Ngày tải lên: 20/02/2014, 18:20

... AB045037 and EMBL AB041732 were obtained. Phylogenetic trees with the nt sequence of the open reading frame (ORF) of their cDNAs and the corresponding aa sequences, in Table 1. Summary of the purification ... susceptible. These findings show that the presence of Val67 is one of the essential factors responsible for the actin-binding capacity of these snake DNases...

Ngày tải lên: 20/02/2014, 23:20

... reinforce the argument that the basic domain should be exposed at the surface of the Tat-containing recombinant proteins and call other reasons to explain the differences in the mechanism of internaliza- tion ... appears unlikely. The number of arginine residues within the Tat peptide appeared to be the main determinant for main- taining a high translocating activi...

Ngày tải lên: 21/02/2014, 03:20

... shown). Determination of the kinetic constants To determine the kinetic constants of the interaction between CD91 and MBL, increasing concentrations of recombinant MBL, ranging from 3 to 30 nm, were injected ... 2010 The Authors Journal compilation ª 2010 FEBS ligand-binding clusters and an 85 kDa beta-chain involved in endocytosis and comprising the transmem- brane a...

Ngày tải lên: 06/03/2014, 01:23