Báo cáo khoa học: The E3 ubiquitin ligase Itch regulates sorting nexin 9 through an unconventional substrate recognition domain pdf
Báo cáo khoa học: The E3 ubiquitin ligase Itch regulates sorting nexin 9 through an unconventional substrate recognition domain pdf
... 2803–2814 ª 2010 The Authors Journal compilation ª 2010 FEBS The E3 ubiquitin ligase Itch regulates sorting nexin 9 through an unconventional substrate recognition domain Claudia Baumann, Cecilia ... this study, we found that the sorting nexin SNX9 is regulated by the E3 Ub ligase Itch. We showed that the interaction is mediated by the SH3 dom...
Ngày tải lên: 22/03/2014, 21:21
Tài liệu Báo cáo khoa học: The yeast ubiquitin ligase Rsp5 downregulates the alpha subunit of nascent polypeptide-associated complex Egd2 under stress conditions docx
... homologue of the aNAC subunit of the human nascent-polypeptide-associated complex. Gene 165, 199 –202. 17 Parthun MR, Mangus DA & Jaehning JA ( 199 2) The EGD1 product, a yeast homolog of human BTF3, ... Franke J, Hartmann E, Wiedmann M, Prehn S & Wiedmann B ( 199 9) Initial characterization of the nascent polypeptide-associated complex in yeast. Yeast 15 , 397 –407. 20 George...
Ngày tải lên: 18/02/2014, 11:20
Tài liệu Báo cáo khoa học: The PA-TM-RING protein RING finger protein 13 is an endosomal integral membrane E3 ubiquitin ligase whose RING finger domain is released to the cytoplasm by proteolysis ppt
... protein-associated domain and the RING domain from the mem- brane. By analyzing microsomes, we showed that the ectodomain is shed into the lumen of vesicles, whereas the C-terminal half, which possesses the RING ... domain and the RING domain from the mem- brane, providing a biochemical basis for understanding the regulation of this family of multimodular endo- somal...
Ngày tải lên: 18/02/2014, 08:20
Tài liệu Báo cáo khoa học: The miRNA-192 ⁄194 cluster regulates the Period gene family and the circadian clock doc
... Regulation, The Netherlands Cancer Institute, Plesmanlaan 121, 1066CX, Amsterdam, The Netherlands Fax: +31(0)20 512 199 9 Tel: +31(0)20 512 20 79 E-mail: r.agami@nki.nl (Received 17 June 20 09, revised ... The miRNA- 192 ⁄ 194 cluster regulates the Period gene family and the circadian clock Remco Nagel 1 , Linda Clijsters 1 and Reuven Agami 1,2 1 Division of Gene Regulation, T...
Ngày tải lên: 18/02/2014, 06:20
Báo cáo khoa học: The CssRS two-component regulatory system controls a general secretion stress response in Bacillus subtilis pdf
... WB800. Funding for the project, of which this work is a part, was provided by the CEU projects BIO4-CT98-0250, QLK3-CT- 199 9-00413, QLK3-CT- 199 9-0 091 7, LSHG-CT-2004-005257, and LSHC-CT- 2004-503468. ... 71, 1 899 – 190 8. 32 Lesuisse E, Schanck K & Colson C ( 199 3) Purification and preliminary characterization of the extracellular lipase of Bacillus subtilis 168, an extreme...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: The crystal structure of annexin Gh1 from Gossypium hirsutum reveals an unusual S3 cluster Implications for cellulose synthase complex formation and oxidative stress response potx
... characteristic annexin fold that has been found in their mammalian and metazoan relatives [ 19] . Structurally, the most striking difference between vertebrate and plant annexins is the convex (membrane-binding) ... of nonplant annexins. A comparison with the structure of the mamma- lian annexin AnxA5 indicates that canonical calcium bind- ing is geometrically possible within the me...
Ngày tải lên: 17/03/2014, 03:20
Báo cáo khoa học: The predominant protein arginine methyltransferase PRMT1 is critical for zebrafish convergence and extension during gastrulation pdf
... 94 -2320-B-040-044, 95 -2320-B-040-042, 96 -2320-B-040-022-MY2 and 98 - 2320-B-040-011-MY3 from National Science Council and CSMU 94 -OM-A-023, 97 -OM-A-136 and 98 OM- A-060 from Chung Shan Medical University. The authors ... morphants. The morphants showed defective convergence and extension and the abnormalities were more severe at the posterior than the anterior parts. Cel...
Ngày tải lên: 28/03/2014, 23:20
Báo cáo khoa học: The myostatin-induced E3 ubiquitin ligase RNF13 negatively regulates the proliferation of chicken myoblasts pot
... 1860–1877. 29 Mahon P & Bateman A (2000) The PA domain: a protease-associated domain. Protein Sci 9, 193 0– 193 4. 30 Luo X & Hofmann K (2001) The protease-associated domain: a homology domain ... SDS-PAGE gel, and then transferred onto a poly(vinylidene difluoride) mem- brane for western blot analysis with the anti-RNF13 monoclonal IgG. The membrane was stripped and re...
Ngày tải lên: 29/03/2014, 08:20
Tài liệu Báo cáo khoa học: The ubiquitin ligase Itch mediates the antiapoptotic activity of epidermal growth factor by promoting the ubiquitylation and degradation of the truncated C-terminal portion of Bid ppt
... Atrophin-1-inter- acting protein 4 ⁄ human Itch is a ubiquitin E3 ligase for human enhancer of filamentation 1 in transforming growth factor-beta signaling pathways. J Biol Chem 2 79, 296 81– 296 90. 8 Ikeda A, Caldwell ... autoimmunity in Itchy mice. Blood 111, 4273–7282. 4 Angers A, Ramjaun A & McPherson P (2004) The HECT domain ligase itch ubiquitinates endophilin and lo...
Ngày tải lên: 16/02/2014, 09:20
Báo cáo khoa học: Characterization of ubiquitin-like polypeptide acceptor protein, a novel pro-apoptotic member of the Bcl2 family pptx
... contain an aliquot from the anti-PU1 affinity chromatography purification step; lanes 2 and 4 contain an aliquot from the hydroxylapatite purification step; lanes 1 and 2, silver-stained; lanes 3 and ... significantly decreased the level of the Ubi-L adduct formation in concanavalin A-activated D.10 cells and the proliferative response of the D.10 cells. These results suggest that...
Ngày tải lên: 17/03/2014, 10:20