Báo cáo khoa học: Bile acids increase hepatitis B virus gene expression and inhibit interferon-a activity pot

... compilation ª 2010 FEBS Bile < /b> acids < /b> increase < /b> hepatitis < /b> B virus gene expression and inhibit interferon-a activity Hye Young Kim 1 , Hyun Kook Cho 1 , Yung Hyun Choi 2 , Kyu Sub Lee 3 and JaeHun Cheong 1 1 ... molecular biology of the hepatitis < /b> B viruses. Annu Rev Biochem 56, 651–693. 4 Antonucci TK & Rutter WJ (1989) Hepatitis < /b>...

Ngày tải lên: 22/03/2014, 21:21

... no detectable b- secretase activity and much less Ab peptide. Inhibition of Ab generation by lowering the activity of the b- secretase may be beneficial for AD treatment. Therefore, Correspondence to B. ... demonstrate that such ribozymes efficiently inhibit b- secretase gene expression at both the mRNA (up to 95%) and the protein (up to 90%) levels. Inhibition of b- site APP...

Ngày tải lên: 08/03/2014, 08:20

... demonstrated by Clark and Mar- shall (1981). It was shown by a series of rather complex examples that, if one did not observe an infinite number of preconditions of the form "A believes that B believes ... A believes that B believes description P applies to R," then it is impossible to guarantee that description D can be used to refer felicitously to R, because it would...

Ngày tải lên: 21/02/2014, 20:20

... plectin ABD (EMBL accession no. AF188008); PLH, human plectin ABD (EMBL accession no. U53204); UTR, utrophin ABD (PDB code 1QAG); FIM, L -fimbrin ABD1 (PDB code 1AOA); DYS, dystrophin ABD (PDB code 1DXX). Ó ... ABD versions (pleABD/2a) from mouse, to a resolution of 1.95 and 2.0 A ˚ . Comparison of pleABD/2a with the ABDs of fimbrin and utrophin revealed structural similarity between plecti...

Ngày tải lên: 07/03/2014, 15:20

... return ‘murder’ but not ‘stop’. Given ‘produce’, we want to return both ‘release’ and ‘generate’ but not ‘fab- ricate’ or ‘hatch’. 1 Taking this into account, we generally define substitutability as the ability ... still a gap between general similarity and entailment: ‘coast’ and ‘hill’ are indeed similar in some way but never substitutable. Our baseline is therefore constrained by a th...

Ngày tải lên: 08/03/2014, 21:20

... significant increase < /b> in ligand sensitivity and a conspicuous reduction in the background reporter gene expression levels in the absence of ligand. As shown in Fig. 4B, the VGCfE Wt gene switch ... 87–95. 6 Bruce W, Folkerts O, Garnaat C, Crasta O, Roth B & Bowen B (2000) Expression profiling of the maize flavo- noid pathway genes controlled by estradiol-inducible transcr...

Ngày tải lên: 16/03/2014, 06:20

... Cbz-Gly-Gly-Ser, Cbz-Gly-Gly-Ala, Cbz-Gly-Gly-Leu, Cbz-Gly-Gly-Val, Cbz-Gly-Gly-Phe and Cbz-Gly-Phe; 236 nm for Cbz-Gly-Gly-Tyr and Cbz-Gly-Tyr; and 302 nm for Cbz-Gly-Gly-Trp and Cbz-Gly-Trp. Initial rates, ... human carboxypeptidase A1; CPA2h, human carboxypepti- dase A2; CPBh, human carboxypeptidase B; CPAb, bovine carb- oxypeptidase A; LysC, lysyl endopeptidase; PCI, potato carbo...

Ngày tải lên: 17/03/2014, 03:20

... BLCT, bovine liver capsule tryptase; BLT, bovine lung tryptase; Boc, t-butyloxycarbonyl; BPTI, bovine pancreatic trypsin inhibitor; DFP, diisopropylfluoro-phosphate; MCA, methyl- coumarin; MUGB, ... partial cDNA (690 bp) encoding a new bovine tryptase isoform (BLT) was obtained from lung mRNA by RT-PCR, using primers N9 and N10, and by subsequent cloning and sequencing. Based on this par...

Ngày tải lên: 17/03/2014, 09:20

... rela- tionship between wild-type p53 and ANX4 expression. ANX4 expression is elevated in renal clear cell carci- noma [31], where p53 gene mutations are rare [32], and p21 expression has been confirmed by ... OVSAHO, OVMANA and OVSAYO were established from metastasis ovarian tumors by Yanagibashi et al. [42]. OVCAR-3 was obtained from the RIKEN (Tsu- kuba, Japan) cell bank, and...

Ngày tải lên: 22/03/2014, 16:20

... APE R e p a i r Damage Single-strand breaks Double-strand breaks Degradation Fig. 2. Potential interactions between mtDNA repair and degrada- tion pathways. ROS induce both single-strand and double-strand breaks in ... well as abasic (AP) sites and base damage. Both base damage and AP sites are converted to single-strand breaks, which in turn are either repaired by BER, or converted t...

Ngày tải lên: 29/03/2014, 22:21