Báo cáo khoa học: Contribution of exofacial thiol groups in the reducing activity of Lactococcus lactis docx

... The role of the active mechanisms in maintaining a low reducing E h7 was thus investigated. Only the effects of compounds that could modify the cell activity were investigated. The activity of ... and increased to 12 lm at the end of growth. The latter thiol concentration was correlated to the reducing activity. Indeed, a decrease in E h7 was linked to a...

Ngày tải lên: 22/03/2014, 21:21

... stability for crystallins is essential in maintaining lens transparency [4]. Determining the mechanism of folding and assembly of these proteins is important for understanding how they can form stable ... concentrations. The d 2 -crystallin in lens was recruited during evolution from argininosuccinate lyase, an enzyme involved in arginine biosynthesis derived from the urea cyc...

Ngày tải lên: 08/03/2014, 08:20

... chain is brefeldin A-insensitive and is inhibited by the proteasome inhibitor clasto-lactacystin b-lactone, resulting in the accumulation of ricin A chains. These stabilized ricin A chains are partly deglycosylated ... pivotal role of the UPR is to maintain ER home- ostasis. Therefore, the presence of mutated proteins that are unable to fold into their native conformation in...

Ngày tải lên: 16/03/2014, 11:20

... expression in the vicinity of the spicules, particularly in the subsurface regions of the animals. In this context, signals were detected intra- and extracellularly. Finally, using whole-mount in situ ... sequencing [55]. In mammals, the protein cryptochrome is one regulator in the complex molecu- lar system of the circadian clock [56]. Focusing on the phylum...

Ngày tải lên: 29/03/2014, 08:20

... promoting an increase in proopiomelanocortin and cocaine and amphetamine regulated transcript. Taken together, these findings provide a compelling argument for the role for malo- nyl-CoA in regulating ... and certain amino acids [16]. A linkage between fatty acid synthesis in the CNS and feeding behavior was uncovered with the finding that systemic or intracerebroventricular adminis...

Ngày tải lên: 14/02/2014, 22:20

... investigated the metal-binding reactivity of the isolated a domain of human metallothionein isoform 1a, with specific emphasis on resolving the debate concerning the cooperative nature of the metal-binding ... the meta- llation mechanisms of the individual domains, in the hope, initially, of simplifying the interpretation of the metallation details of the...

Ngày tải lên: 19/02/2014, 00:20

... ele- ments, very little is known about their role in DIDO activity. The combination of domains (domain shuffling) is a driving force in Eukarya in the acquisition of Keywords CGBP; DATF1; DIDO1; DIO; ... from the other bran- ches, which was indeed predicted. The other main group, obtained 97% of the time in 20 740 explored trees, contained the DIDO PHD sequences clus...

Ngày tải lên: 07/03/2014, 21:20

... com- plete loss of any of the three CCM proteins within endothelial cells lining the cavernous capillary cavities. These data were an important step towards the elucidation of the mechanisms of this ... towards the understanding of the mechanisms of this disorder. This minireview summarizes the advances in CCM molecu- lar genetics and the remaining gaps in this...

Ngày tải lên: 15/03/2014, 10:20

... whether the SLe x level of InR on insulin-responsive cells in diabetic patients was changed. This may reveal the role of the sugar chains on InR in the pathogenesis of diabetes. In summary, the ... higher than in the corresponding control cells cultured in the absence of insulin. The response to insulin stimulation was proportional to the expression of a1...

Ngày tải lên: 16/03/2014, 12:20

... staining of the gel indicates that the fluorescing protein is one of the major components of soluble proteins in the crude extract. The surface of the fluorescing protein carries negative charge in ... cellular retinal-binding protein; CRBP, cellular retinol-binding protein; IRBP, interphotoreceptor retinoid-binding protein; RBP, retinol-binding protein. Note: The nucl...

Ngày tải lên: 17/03/2014, 03:20