Báo cáo khoa học: Hepatocyte growth factor activator (HGFA): pathophysiological functionsin vivo potx

... February 2010) doi:10.1111/j.1742-4658.2010.07640.x Hepatocyte growth factor activator (HGFA) is a serine protease initially identified as a potent activator of hepatocyte growth factor ⁄ scatter factor. Hepatocyte growth factor ⁄ scatter factor ... some types of cancer. Abbreviations HAI, hepatocyte growth factor activator inhibitor; HGF, hepatocyte growth...

Ngày tải lên: 22/03/2014, 21:21

... is impaired in hepatocyte growth factor activator- deficient mice. Gastroenterology 127, 1423–1435. 20 Kataoka H & Kawaguchi M (2010) Hepatocyte growth factor activator (HGFA): pathophysiological functions ... system. Abbreviations FXII, coagulation factor II; HGF, hepatocyte growth factor; HGFA, hepatocyte growth factor activator; tPA, tissue-type plasmi...

Ngày tải lên: 15/03/2014, 11:20

... substrates pro -hepatocyte growth factor and pro-macrophage-stimulating protein. Abbreviations EGF, epidermal growth factor; HAI, hepatocyte growth factor activator inhibitor; HGFA, hepatocyte growth factor ... (2009) Hepatocyte growth factor activator is a serum activator of single-chain precursor macro- phage-stimulating protein. FEBS J 276, 3481–3490. 3 Kata...

Ngày tải lên: 15/03/2014, 11:20

... protein C; BrdU, bromodeoxyuridine; HAI, hepatocyte growth factor activator inhibitor; HGF, hepatocyte growth factor; HGFA, hepatocyte growth factor activator; hPCI-Tg, human protein C inhibitor-transgenic; ... with the serine protease hepatocyte growth factor activator (HGFA), inhibiting the HGFA-catalyzed activation of the single- chain hepatocyte growth fa...

Ngày tải lên: 22/03/2014, 21:21

... that HGFA is a major serum activator of pro-MSP. Abbreviations CHO, Chinese hamster ovary; HGF/SF, hepatocyte growth factor/ scatter factor; HGFA, hepatocyte growth factor activator; LPS, lipopolysaccharide; ... been implicated. In this article, we report that hepatocyte growth factor activator (HGFA), a serum proteinase which activates hepatocyte growth factor in...

Ngày tải lên: 29/03/2014, 23:20

... Hospital, Nagoya, Japan Identification of epidermal growth factor, epidermal growth factor receptor and ERBB family proteins Epidermal growth factor (EGF) was originally isolated by Stanley Cohen ... carcinoma; EGF, epidermal growth factor; EGFR, epidermal growth factor receptor; EML4, echinoderm microtubule-associated protein-like 4; NRG, neuregulin; STAT, signal transducer...

Ngày tải lên: 16/02/2014, 09:20

... with mAb to epidermal growth factor receptor in colorectal cancer Cetuximab is a chimeric mouse–human mAb that tar- gets the extracellular domain of the epidermal growth factor receptor (EGFR) ... MINIREVIEW Epidermal growth factor receptor in relation to tumor development: EGFR-targeted anticancer therapy Isamu Okamoto Department ... however, revealed that only 1.2% of the KRAS m...

Ngày tải lên: 16/02/2014, 09:20

... epidermal growth factor- signaling-regulated miRNA, may function as a metastatic suppressor. Abbreviations ECM, extracellular matrix; EGF, epidermal growth factor; EGRF, epidermal growth factor receptor; ... diseases. In severe cases, aberrant growth factor signaling may even give rise to tumors. Among these pathways, epidermal growth Keywords epidermal growth factor recep...

Ngày tải lên: 07/03/2014, 00:20

... Cytokine Growth Factor Rev. 11, 97–102. 46. Kim, S.J., Park, K., Rudkin, B.B., Dey, B.R., Sporn, M.B. & Roberts, A.B. (1994) Nerve growth factor induces transcription of transforming growth factor- b1 ... TGF-b-resistant. Keywords:PC12cells;Smads;crosstalk;nervegrowth factor; transforming growth factor- b. Proteins of the transforming growth factor b (TGF-b) family are...

Ngày tải lên: 16/03/2014, 16:20

... recruitment ⁄ sequestration of the other factors and thus a loss of factor factor interaction, either directly or through mediation of a cofactor or another transcription factor. One example of this is ... 4066–4075 ª 2010 The Authors Journal compilation ª 2010 FEBS 4075 Hepatocyte nuclear factor- 4 a interacts with other hepatocyte nuclear factors in regulating transthyretin gene exp...

Ngày tải lên: 23/03/2014, 03:20