... ID3G60), 11 common residues were found for both P-gpmolecules (A and B) in the unit cell; mouse Tyr3 03 (human Tyr3 07) , Leu 335 (human L 339 ) and Ser725 (human Ala729) were also involved in the ... [20, fig. 3] , mouse Ser725 (human Ala729) and Ala981 (human Ala985) for the ligand in molecule A, and Phe71 (human Phe72), Leu 971 (human Leu 975 ) and Ala981 (human Ala985) for the ligand in mole-cule ... A 977 ).I. K. Pajeva et al. Comparison of open and closed models of human P-gpFEBS Journal 276 (2009) 70 16 70 26 ª 2009 The Authors Journal compilation ª 2009 FEBS 70 19Phe71 (human Phe72) and...