Báo cáo khoa học: Dynamics of flavin semiquinone protolysis in L-a-hydroxyacid-oxidizing flavoenzymes – a study using nanosecond laser flash photolysis doc

... Dynamics of flavin semiquinone protolysis in L -a- hydroxyacid-oxidizing flavoenzymes – a study using nanosecond laser flash photolysis Lars Lindqvist 1 , Simona Apostol 1, *, Chaibia El Hanine-Lmoumene 1 and ... compared with flavodoxin affect the fate of e aq ) is unclear. Flavin semiquinone spectra The absorption spectra of the half-reduced flavin...

Ngày tải lên: 22/03/2014, 21:20

... folds ‘NAD(P)- binding Rossmann-fold domain’, ‘FAD ⁄ NAD(P)-binding domain’ and ‘Nucleotide-binding domain’. The dataset was scrutinized and only proteins utilizing FAD or NAD(P) in a typical manner ... non- Rossmann fold. Among the NAD-binding proteins a total of 10 are false negatives: four are lost during the database search, five are classified as false, and one is classified as NADP...

Ngày tải lên: 23/03/2014, 10:21

... parameters of each leaflet separately, including the whole acyl chain and the ‘plateau region’ described above. Taking the approach applied by Bachar and Becker [18], we analyzed the lipids in ... the extracellular face), at the same time as increasing lipid order in the cytofacial leaflet. Simulations of melittin in DPPC lead to an interest- ing comparison with the Ab-DPPC simulation...

Ngày tải lên: 18/02/2014, 08:20

... Human a- syn is a 140-amino acid (aa) protein, and b-syn is a 134-aa protein. Each of the synucleins is composed of an N-terminal lipid-binding domain containing 11 residue repeats and a C-terminal acidic ... structure of a- syn showed that a- syn homodimers can adopt nonpropagating (head-to-tail) and propagating (head-to-head) conformations. Propagating a- syn dimers on the m...

Ngày tải lên: 23/03/2014, 09:21

... 10. 106 Takaki E, Fujimoto M, Sugahara K, Nakahari T, Yonemura S, Tanaka Y, Hayashida N, Inouye S, Takemoto T, Yamashita H et al. (2006) Maintenance of olfactory neurogenesis requires HSF1, a major ... domain of HSF4 is associated with autosomal dominant lamellar and Marner cata- ract. Nat Genet 31, 27 6–2 78. 98 Smaoui N, Beltaief O, BenHamed S, M’Rad R, Maazoul F, Ouertani A, Chaab...

Ngày tải lên: 18/02/2014, 04:20

... obtained using the sense primer 5¢ -ATC ATC TCC ATC GAC TAC TCC CTG-3¢, the antisense primer 5¢-AAG AAT TCT AGA TTA ATG GTG ATG ATG GTG ATG ATG GTG TGG GGT CAG CGG TGC AGC AGG GGG GGT-3¢ (XbaI ... conformational change that exposes and ⁄ or increases the lipid-binding area of the enzyme. A direct demonstration of this presumed conformational change will have to await the solving of...

Ngày tải lên: 18/02/2014, 11:20

... 613 Destabilization of psychrotrophic RNase HI in a localized fashion as revealed by mutational and X-ray crystallographic analyses Muhammad S. Rohman 1 , Takashi Tadokoro 1 , Clement Angkawidjaja 1 , ... Gene splicing by overlap extension: tailor-made genes using the polymerase chain reaction. Biotechniques 8, 52 8–5 35. 34 Kanaya S, Katsuda C, Kimura S, Nakai T, Kitakuni E, Nakamu...

Ngày tải lên: 18/02/2014, 13:20

... positively charged amino acid side chains, R397 and R120, are also involved in fosfomycin binding, and in view of the multitude of interactions, it was assumed that deletion of a single interaction ... of UDP-N-acetylmuramic acid) (A) and inactivation mechanism of MurA by fosfomycin as a result of the covalent linkage between Cys115 of MurA and fosfomycin (B). Ó FEBS 200...

Ngày tải lên: 19/02/2014, 13:20

... relatively insignificant (headings, titles, bibliography lists, etc.). Main clauses and dependent clauses were not separated in the analysis. Out of a total of 2914 clauses thus analyzed, the ... correspondence. IN HIS " ;A Preliminary Study of Russian", 1 Kenneth E. Harper states that a "word-for-word translation of Russian is adequate for under-...

Ngày tải lên: 19/02/2014, 19:20

... implications for in ammation, heart disease, and cancer. Pharmacol Rev 52, 67 3–7 51. 3 Hrazdina G & Jensen RA (1992) Spatial organization of enzymes in plant metabolic pathways. Annu Rev Plant ... human ligandins: characteri- zation of a binding-site peptide. Biochim Biophys Acta 955, 29 6–3 00. 52 Gregus Z & Klaassen CD (1982) Role of ligandin as a binding protein a...

Ngày tải lên: 20/02/2014, 01:20