Báo cáo khoa học: Structure–cytotoxicity relationships in bovine seminal ribonuclease: new insights from heat and chemical denaturation studies on variants ppt

... compilation ª 2010 FEBS Structure–cytotoxicity relationships in bovine seminal ribonuclease: new insights from heat and chemical denaturation studies on variants Concetta Giancola 1 , Carmine Ercole 1 , ... of bovine seminal ribonuclease in which the chains swap their N-termini; M=M, unswapped dimer of bovine seminal ribonuclease; NCD, noncovalent dim...

Ngày tải lên: 22/03/2014, 17:20

... difference in absorbance between 10 and 16 min for the sample containing LPS only, DD2 represents the difference in absorbance between 10 and 16 min for the samples containing LPS and different con- centrations ... strong d ad NOEs, indicating that Pro7 in fowlicidin-1 has the trans configuration. Stereo-specific assignments of b-methylene protons were obtained by using information...

Ngày tải lên: 30/03/2014, 11:20

... neuronally active a-conotoxins, in conjunction with activity studies, have provided clues to understanding the complexity involved in binding to the nAChR. A summary of this structural information ... solution conformation of an antitoxic analogue of alpha-conotoxin GI: identification of a common nicotinic acetylcholine receptor alpha 1-subunit binding surface for small ligands and alph...

Ngày tải lên: 19/02/2014, 12:20

... an information coefficient) comparing either the logically combined vectors or individual vec- tors A or B with vector C, conditioned on the infor- mation available in vector C, and where f is one ... genes identified in GLUT10-containing profiles seen in Fig. 3 seem to play some potential role in cancer and are involved in informative logical combinations with GLUT10. Gliomal ma...

Ngày tải lên: 07/03/2014, 21:20

... suggesting that it can be a proton donor for the leaving O5¢ RNA strand. Taking into consideration the conformation of both arginine side chains in the RNase Sa2–mononucleotide structures, Arg67 and ... num- bering) and forms a hydrogen bond network with the enzyme [14]. Tyr42 (in RNase T1) or an arginine (in RNase Sa, barnase, and binase) has an important role in closing the guan...

Ngày tải lên: 18/02/2014, 11:20

... domain of the MyroBP family possesses different ligand-bind- ing properties, thereby providing a broad binding speci- ficity. In some proteins containing tandem homologous domains, inter-domain interactions ... protein with unknown structure. At3g16450.1 has been classified as a myrosinase-bind- ing protein-like protein. Myrosinase is a glucosinolate- degrading enzyme [4], and myrosinase-bi...

Ngày tải lên: 18/02/2014, 14:20

... small heat shock proteins hsp27 and aB-crystallin in Parkinson’s disease. NeuroReport 10, 2273–2276. 10 Head MW & Goldman JE (2000) Small heat shock pro- teins, the cytoskeleton, and inclusion ... are found in most cell types in most organisms, and their expression is upreg- ulated under a range of stress conditions, such as heat, oxidative conditions, pH changes, infect...

Ngày tải lên: 07/03/2014, 04:20

... Xiong, Qun Liu, and Shouxun Lin. 2006. Maxi- mum entropy based phrase reordering model for sta- tistical machine translation. In Proceedings of the 21st International Conference on Computational ... (2) 3.1 Training For the convenience of training, we invert the or- der in each sentence in the training data, i.e., from the original order (w 1 w m ) to the reverse order (w m w 1...

Ngày tải lên: 07/03/2014, 22:20

... to subclone the mutation-contain- ing pFOX fragments into vector pGSB1, a pUC19 deriva- tive containing the complete EXG ORF. The entire ORFs containing each mutation were then cloned into the ... through extensive intramolecular and intermolecular hydrogen bonding involving planar amino acid side chains and sugar hydroxyl groups. In addition to these conserved interactions at the )1 si...

Ngày tải lên: 15/03/2014, 23:20

... neamine and paromomycin, at concentrations Table 4. Percent inhibition of 12G5 mAb binding to CXCR4 by R-peptide and their conjugates, and r-peptides and their conjugates, to neamine and neomycin. ... anti-HIV-1 and mode of action of neomy- cin and neamine conjugated at specific sites to arginine 6- and 9-mers d- and l-arginine peptides (APACs). The d-APACs inhibit the infect...

Ngày tải lên: 16/03/2014, 06:20