Báo cáo khoa học: MNB⁄ DYRK1A as a multiple regulator of neuronal development pdf

... Signal 21,1626–1633.84 Kurabayashi N, Hirota T, Sakai M, Sanada K & Fuk-ada Y (2010) DYRK 1A and glycogen synthase kinase3beta, a dual-kinase mechanism directing proteasomaldegradation of ... Sharma S, Nardone J, Tanasa B, Iuga A, Srikanth S, Okamura H, Bolton D, Feske S, Hogan PGet al. (2006) A genome-wide Drosophila RNAi screenidentiﬁes DYRK-family kinases as regulators of NFAT.Nature ... that MNB⁄ DYRK 1A kinase couldact at several levels in a multifaceted manner, integrat-ing several cellular responses within a given neuronal process.MNB ⁄ DYRK 1A also displays a rather varied...

Báo cáo khoa học: "GAMR VIEWED AS A FUNCTIONING PART OF A COGNITIVES SERM A YTM" pot

... spreading activation, the syntactic category aspect of each meaning in turn activates the category's meaning in the grammar space representation. Part of the grammatical meaning of any ... (Cf Studies of agrammatic and Broca's aphasia as described in Goodenough, Zurif, and Weintraub, 1977; Goodglass, 1976; Goodglass and Berko, 1960; Goodglass, Gleason, Bernholtz, and Hyde, ... phonetic, categorially accessed meanings, grammar, and pragmatic or local context, receive support as separately definable knowledge within studies of aphasia. There is a vast literature concerning...

Báo cáo khoa học: "Lexical surprisal as a general predictor of reading time" potx

... 20 years of research. Psy-chological Bulletin, 124:372–422.Brian Roark, Asaf Bachrach, Carlos Cardenas, andChristophe Pallier. 2009. Deriving lexical and syn-tactic expectation-based measures ... R´ejean Ducharme, Pascal Vincent,and Christian Jauvin. 2003. A neural probabilis-tic language model. Journal of Machine LearningResearch, 3:1137–1155.Marisa Ferrara Boston, John Hale, Reinhold ... psychological accu-racy of each model (χ2(2) values) plotted againstits linguistic accuracy (i.e., its quality as a lan-guage model, measured by the negative aver-age surprisal on the experimental...

Báo cáo khoa học: Neuropeptide S as a novel arousal promoting peptide transmitter pdf

... Functionally, central administration of NPS increases locomotor activity in both naı¨ve and habituated mice. Italso signiﬁcantly increases wakefulness and decreases paradoxical (rapideye ... area, the principle 5 sensory nucleusand the lateral parabrachial nucleus of the brain-stem. A small number of scattered NPS-positive cellswere found in other brain areas, such as amygdalaand ... (ACh) appears to serve a dual role:ACh release coincides with elevated arousal as well as the onset of paradoxical sleep, also known as rapid eyeKeywordsanxiety; brainstem; locus coeruleus;neuropeptide;...

Báo cáo khoa học: Intermittent hypoxia is a key regulator of cancer cell and endothelial cell interplay in tumours pot

... enzymes that lead to extracellular matrix degra-dation (matrix metalloproteases) [75–78]. In addition,NF-jB activation was reported as an early event inmalignant transformation in vitro [79], and ... and not to an increase in itsstabilization. Indeed, although HIF- 1a may be extre-mely rapidly degraded when cells are reoxygenated, itsdegradation after 4 min of reoxygenation was notassayed ... Rogers AE et al. (2000) Activation of NF-kap-paB ⁄ Rel occurs early during neoplastic transformation of mammary cells. Carcinogenesis 21, 871–879.80 Rayet B & Gelinas C (1999) Aberrant rel...

Tài liệu Báo cáo khoa học: Pharmacologic chaperoning as a strategy to treat Gaucher disease ppt

... tolm) and stabilize just one protein and thus are gener-ally protein and disease selective, if not speciﬁc.Many of the clinically important Fabry disease-asso-ciated a- galactosidase A variants ... 1432–1444.16 Ishii S, Kase R, Sakuraba H & Suzuki Y (1993)Characterization of a mutant alpha-galactosidasegene-product for the late-onset cardiac form of Fabrydisease. Biochem Biophys Res ... Fabry disease [18,19]. A thorough review of a- galactosidase A pharmacologic chaperones for Fabrydisease is provided in an accompanying minireview byFan & Ishii [20].The GD-associated N370S,...

Tài liệu Báo cáo khoa học: Phage-display as a tool for quantifying protein stability determinants pptx

... recovereddifferentially based on varying stabilities. Remarkably, wehave found that, at least in some circumstances, a quanti-tative correlation to biophysical data can be obtained from a statistical analysis of ... the association of the variable heavy chain (VH)withprotein A was used as a surrogate for direct stabilitymeasurements. The VHdomains in camelid heavy chainantibodies are most similar to ... San Francisco, CA, USATo address questions of protein stability, researchers haveincreasingly turned to combinatorial approaches that permitthe rapid analysis of libraries of protein variants....

Tài liệu Báo cáo khoa học: Control analysis as a tool to understand the formation of the las operon in Lactococcus lactis doc

... CP-pyk(5¢-ACGACTAGTGGATCCATNNNNNAGTTTATTCTTGACANNNNNNNNNNNNNNTGRTATAATNNNNAAGTAATAAAATATTCGGAGGAATTTTGAAATGAATAAACGTGTAAAAATCG-3¢)(N¼ A, T, G, C) and pyk-back (5¢-CTCTACATGCATTTCAACAATAGGGCCTGTC-3¢) ... (5¢-TGGTACTCGAGCAATTTCTGAAGGTATCGAAG-3¢) and pyk2 (5¢-GGAAGGATCCTTGTGTTTTTCTCCTATAATG-3¢) anddownstream to pyk using primer pyk3 (5¢-GGAAGGATCCTTTGTCAATTAATGATCTTAAAAC-3¢) and pyk4(5¢-CTAGTCTAGATGAGCTCCAGAAGCTTCC-3¢) wereampliﬁed. ... À a lasÞÃð1 À eÀ6 a 2:1lasÞÀ33:2 (User deﬁned),Jlactate a lasÞ¼0:919 Ãð129 À a lasÞÃð1 À eÀ6 a 2:1lasÞÀ75:2 (Us erdeﬁned), Jacetate a lasÞ¼0:1135 ÃðÀ30:3 À a lasÞÃð1 À eÀ6 a 3:3lasÞþ4:66...

Tài liệu Báo cáo khoa học: "Sentence generation as a planning problem" pptx

... Actions have a number of param-eters, as well as a precondition and effect, both of which are logical formulas. When a planner tries toapply an action, it will ﬁrst create an action instanceby ... (Fikes and Nils-son, 1971). In this paradigm, a planning state isdeﬁned as a ﬁnite set of ground atoms of predicatelogic that are true in this state; all other atoms are as- sumed to be false. Actions ... lex-icalized tree-adjoining grammars (LTAG; Joshi andSchabes (1997)). An LTAG grammar consists of a ﬁnite set of lexicalized elementary trees as shown inFig. 1a. Each elementary tree contains exactly...

Tài liệu Báo cáo khoa học: Infrared spectroscopy as a tool for discrimination between sensitive and multiresistant K562 cells doc

... interclass variance andthe smallest intraclass variance, and constructs a linearcombination of the variables to discriminate between theclasses. The rule i s constructed with training set of samples,and ... with a window of ﬁvewavenumbers, assuming that adjacent wavenumbers arehighly corr elated. A population o f 3 2 solutions was built ateach generation, and e valuated. The algorithm stopped a ... cells a d ecrease of the absorptions assigned to fatty a cids and phospholipidsrelative to their protein content. This qua ntitative changewas accompanied by qualitative modiﬁcation, as themethyl/methylene...

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Từ khóa: báo cáo khoa học mẫu báo cáo khoa học y học báo cáo khoa học sinh học báo cáo khoa học nông nghiệp báo cáo khoa học lâm nghiệp báo cáo khoa học thủy sản Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thống Báo cáo quy trình mua hàng CT CP Công Nghệ NPV Nghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt nam Một số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTP Nghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THz Nghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt nam Giáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôit Giáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôit Giáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôit ĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDE Thơ nôm tứ tuyệt trào phúng hồ xuân hương Thiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khí Chuong 2 nhận dạng rui ro BT Tieng anh 6 UNIT 2 Tranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vật Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vật Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vật TÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ