Báo cáo khoa học: The role of cytochrome P450 monooxygenases in microbial fatty acid metabolism pdf

... tight binding affinity was demonstrated towards lauric acid, resulting in the synthesis of mainly x-1 hydroxylated lauric acid, suggesting a role in the lipid oxidative metabolism. Interestingly, the ... occurring in the soil. Furthermore, branched chain fatty acids make up 80% of the fatty acid content of the Bacillus sp. mem- branes and when the hydroxyl...

Ngày tải lên: 22/03/2014, 16:21

... antigen in itself [7,20]. At least for these antibodies, the role of the V L domain might be to increase the affinity by supporting the V H domain. The phenomenon may also be observed in the chain ... Although the Fv was designed based on HyHEL-10, it is not clear whether or not H39 is dominantly tuning the V H ⁄ V L interaction of other Fvs, including HyHEL-10. In...

Ngày tải lên: 07/03/2014, 12:20

... example, in the case of question Q209: “Who invented the paper clip ?”, the expected answer type is PERSON and so is the subject of the verb invented , lexicalized as the nominalization inventor. ... hypernyms in the answer se- mantic form. Step 3: The assessment of the similarities of dependencies. In the third step, two classes of similar dependencies are...

Ngày tải lên: 08/03/2014, 05:20

... selective inhibitor of Glc6P hydrolysis [31], for evaluating the role of Glc6P, we determined the effect of different inhibitor concentrations on the Glc6P content and the rate of glycogen synthesis in hepatocytes ... that the increase of Glc6P in the presence of S4048 was caused by the inhibition of Glc6P hydro- lysis in the absence of detectable chang...

Ngày tải lên: 16/03/2014, 14:20

... Nuijens Pharming, Archimedesweg, Leiden, the Netherlands Lactoferrin (LF) is an iron-binding glycoprotein of the innate host defence system. To elucidate the role of N-linked glycosylation in protection of ... such as the pancreatic enzyme trypsin has been suggested [19,20]. The experiments described herein further elucidate the role of N-linked glycosylation in t...

Ngày tải lên: 30/03/2014, 13:20

... indicating that the effect of APMA on ACE shedding was not as a result of over-expression of the protein. Together these data confirm that APMA induces the shedding of ACE but not the shedding of ... both ADAM10 and TACE are involved in the shedding of APP, neither ADAM is involved in the shedding of ACE. Furthermore we show that APMA can distinguish between the...

Ngày tải lên: 30/03/2014, 14:20

... through the exchange between subunits of either their N-ter- minal, or their C-terminal ends [33–35]. We found that the behavior with the model membrane of the dimer in which the C-terminal ends ... ‘r’) and variation of the inclination (inclination angle ‘i’) with respect to the plane of the membrane (parallel to the xy plane). Cter and Nter are the C-terminal a...

Ngày tải lên: 19/02/2014, 06:20

... undergoes fusion with the membrane of intra-endosomal vesicles contained within MVBs, thereby releasing the nucleocapsid into the lumen of these vesi- cles. Then, the capsid uses these intra-endosomal ... mild developmental delay. The protein defective in this disorder is also a NHEJ protein. The distinct clinical features of the patients will be discussed in the con...

Ngày tải lên: 19/02/2014, 07:20

... likely that the N-terminal domain is involved in protein–protein interactions with other hydrophilic domains of neighboring integral membrane subunits, and interspecies interactions are incompatible. From ... as a nother identification of the complex at the position o f the histochemical stain in the left panel. Antisera against the SDHC subunit of complex II and against...

Ngày tải lên: 19/02/2014, 16:20

... N-linked oligosaccharide side-chains are important for the GABA transport activity. 1-Deoxymannojirimycin inhibits the GABA-uptake of GAT1 In order to gain further insight into the role of the terminal ... results in reduction of the stability of GAT1 In order to study the in uence of the N-glycosylation and N-linked oligosaccharides on protein stability, the...

Ngày tải lên: 19/02/2014, 17:20