Báo cáo khoa học: Energetic coupling along an allosteric com

Báo cáo khoa học: Energetic coupling along an allosteric communication channel drives the binding of Jun-Fos heterodimeric transcription factor to DNA docx

... allosteric communication channel drives the binding of Jun-Fos heterodimeric transcription factor to DNA Kenneth L. Seldeen, Brian J. Deegan, Vikas Bhat, David C. Mikles, Caleb B. McDonald and Amjad ... propagation of information from one monomer to another, which is often the hall- mark of binding of dimeric transcription factors to palindromic DNA...

Ngày tải lên : 22/03/2014, 16:20

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Tài liệu Báo cáo khoa học: "ModelTalker Voice Recorder – An Interface System for Recording a Corpus of Speech for Synthesis" ppt

... within an acceptable range. This feedback mechan- ism also helps to eliminate cases in which the system is unable to accurately track the pitch of an utterance. In these cases, the utterance ... recorded, the user receives feedback on the overall quality of the utterance. Specifically, the user receives feedback on the pitch, the overall amplitude, and t...

Ngày tải lên : 20/02/2014, 09:20

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Báo cáo khoa học: Relationship between functional activity and protein stability in the presence of all classes of stabilizing osmolytes ppt

... complexes [29]. On the other hand, k cat ⁄ K m is an apparent second-order rate constant that refers to the properties and the reaction of the free enzyme and free substrate [29]. We have therefore esti- mated ... than those in the absence of sugars, i.e. K m is decreased. On the other hand, this change in conformation results in a decrease in k cat , the turnover number...

Ngày tải lên : 07/03/2014, 00:20

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Báo cáo khoa học: "COMMON TOPICS AND COHERENT SITUATIONS: INTERPRETING ELLIPSIS IN THE CONTEXT OF DISCOURSE INFERENCE" ppt

... VP-ellipsis patterns with other types of anaphora, for instance it can be cataphoric and can locate antecedents from clauses other than the most immediate one. 52 one of two ways. The syntactic VP ... terms of two features: (1) whether the form leaves behind an empty constituent in the syntax, and (2) whether the form is anaphoric in the semantics. In subsequent se...

Ngày tải lên : 08/03/2014, 07:20

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Báo cáo khoa học: X-ray crystallography, CD and kinetic studies revealed the essence of the abnormal behaviors of the cytochrome b5 Phe35ﬁTyr mutant pdf

... Tyr35 and the heme group in the Phe35ﬁTyr mutant. The overall structure of the Phe35ﬁTyr mutant is basically the same as that of the wild-type Tb 5 . The r.m.s. deviation for a total of 82 Ca atoms ... extends into the solvent and does not form any hydrogen bond with the protein atoms. The former propionate displays the conserved conformation in the structures o...

Ngày tải lên : 08/03/2014, 10:20

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Báo cáo khoa học: Direct CIII–HﬂB interaction is responsible for the inhibition of the HﬂB (FtsH)-mediated proteolysis of Escherichia coli r32 by kCIII docx

... general mode of CIII activity, or does it apply only for CII? We examined the mode of the inhibitory action of CIII on proteolysis of the heat shock sigma factor r 32 , another substrate of HﬂB. Like ... min in the presence of His 6 –CIII or CIIIC (up to 200 lM) are shown in the upper panels. Numbers on the top of each lane indicate the concentration of His...

Ngày tải lên : 23/03/2014, 10:20

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Báo cáo khóa học: CD38 is expressed as noncovalently associated homodimers on the surface of murine B lymphocytes doc

... Upon densito- metric analysis of the immunoblots it became clear that the amount of CD38 expressed on the plasma membrane and the total amount of CD38 expressed by the various transfectants correlated ... NP-40 (lane 1), Triton X-100 (lanes 2 and 3), digitonin (lanes 4 and 5), Chaps (lanes 6 and 7) or deoxy-BigChap (lanes 8 and 9). Lysates were immunoprecipitated with antibody...

Ngày tải lên : 23/03/2014, 12:20

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Báo cáo khoa học: "A Feedback-Augmented Method for Detecting Errors in the Writing of Learners of English" docx

... types of : , , and that denote the contexts consisting of the noun phrase that the tar- get noun heads, words to the left of the noun phrase, and words to its right, respectively. Then the template ... conﬁdence of ratio is measured by the reciprocal of variance of the ratio (Tanaka, 1977). Variance is calculated by (6) where denotes the number of samples u...

Ngày tải lên : 23/03/2014, 18:20

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Báo cáo khoa học: b3-Adrenoceptor knockout in C57BL/6J mice depresses the occurrence of brown adipocytes in white fat pptx

... h) before the beginning of each experiment. They were then divided into three groups, one maintained at 24 °Candthe other two exposed to cold (6 °C) for either two or 10 days. The fat pads along the ... in the WAT depot and it was therefore not possible to assess the number of these cells and to compare it to that in WT mouse WAT. Genital pads of b 3 KO mice were 1.5...

Ngày tải lên : 23/03/2014, 20:22

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Báo cáo khoa học: cGMP and glutathione-conjugate transport in human erythrocytes The roles of the multidrug resistance-associated proteins, MRP1, MRP4 and MRP5 pot

... transport in human erythrocytes and so the low afﬁnity transport of DNP-SG and the transport of cGMP may be mediated by one and the same transporter. The character- istics of transport indicate ... were compared using an F-testontheratioofthevariance associated with the reduction in degrees of freedom to the variance of the ﬁt with the smaller number of degrees...

Ngày tải lên : 23/03/2014, 21:20

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