Báo cáo khoa học: Surface-enhanced vibrational spectroscopy for probing transient interactions of proteins with biomimetic interfaces: electric field effects on structure, dynamics and function of cytochromec doc

... MINIREVIEW Surface-enhanced vibrational spectroscopy for probing transient interactions of proteins with biomimetic interfaces: electric ﬁeld effects on structure, dynamics and function of cytochrome ... diffusion of the reactant along thesurface of a macromolecular target, a reorientationcorresponding to a rotational diffusion within theinteraction domain, and eventually mutual conforma-tional ... frequencies and bandintensities of vibrational transitions represent a uniqueﬁngerprint of the speciﬁc conformation of a molecule[10]. Both techniques, however, are associated with lowsensitivity and...

Báo cáo khoa học: Macromolecular NMR spectroscopy for the non-spectroscopist pot

... these calculations, the motion of the molecule issimulated for sufﬁcient time to allow sampling of largeregions of conformational space with the aim of con-verging on the structure with the global ... 2011 FEBSconformation as a result of the lack of NOE informa-tion or else an unrealistic one as a result of an averag-ing of the NOEs and coupling constants. Thus, theseregions of the protein ... particularly for the backbone / angles. Inaddition, both / and w backbone dihedral angles canbe robustly estimated based on the correlation betweenbackbone conformation and the chemical shifts of the1Ha,13C’,13Ca,13Cband...

Báo cáo khoa học: Macromolecular NMR spectroscopy for the non-spectroscopist: beyond macromolecular solution structure determination potx

... unparalleled ability of NMR to monitor binding interactions over a wide range of afﬁnities,molecular masses and solution conditions. We discuss the use of NMR tomeasure the dynamics of proteins at the ... use with isotope labeling for studies of macromo-lecular conformation and intermolecular interactions. Q Rev Biophys 23, 39–96.32 Breeze AL (2000) Isotope-ﬁltered NMR methods for the study of ... B and C are well-folded and have conformations that closely resemble the wild-typedomain, whereas D and E are not correctly folded and thereforeshould not be used for any subsequent functional...

Tài liệu Báo cáo khoa học: "Generalized Expectation Criteria for Semi-Supervised Learning of Conditional Random Fields" pdf

... thesemethods can often ﬁnd good solutions, both are quitesensitive to the selection of auxiliary information, and making good selections requires signiﬁcant in-sight.23 Conditional Random FieldsLinear-chain ... distance function ∆, a target expectationˆf, data D, a function f , and a model distribution pθ, the GE criterion objective function term is ∆ˆf, E[f(x)]. For the purposes of this paper, ... predicted label distribution on theunsupervised data match a target distribution. Notethat supervision here consists of the the full distribu-tion over labels (i.e. conditioned on the maximumentropy...

Báo cáo khoa học: A mouse model for in vivo tracking of the major dust mite allergen Der p 2 after inhalation docx

... productions and accessory function of alveolar macrophages: implica-tions for allergic sensitization and inﬂammation.J Immunol 170, 528–536.8 Yu CK & Chen CL (2003) Activation of mast ... i.t.instillation of FITC–OVA [23,24], we chose the 24 htime point for a closer evaluation of the tissue distribu-tion of [75Se]Der p 2 upon i.t. administration.Tissue distribution of radioactivity ... 2 and thisband could only be detected in the lung. Autoradio-grams of separated liver and thoracic lymph node pro-teins revealed a radioactive band of  25 kDa in liver and bands of  30 and...

Báo cáo khoa học: "An Extensible Architecture for Integrating Natural Language Processing Techniques with Wikis" docx

... Proceedings of the ACL-HLT 2011 System Demonstrations, pages 74–79,Portland, Oregon, USA, 21 June 2011.c2011 Association for Computational LinguisticsWikulu: An Extensible Architecture for Integrating ... IntroductionWikis are web-based, collaborative content author-ing systems (Leuf and Cunningham, 2001). As theyoffer fast and simple means for adding and editingcontent, they are used for various ... users add newcontent to a wiki there is the danger of duplicatingalready contained information. In order to avoid du-plication, users would need comprehensive knowl-edge of what content is already...

Báo cáo khoa học: "A Formula Finder for the Automatic Synthesis of Translation Algorithms" docx

... “Linguistic and Machine Methods for Compil- ing and Updating the Harvard Automatic Dictionary,” Preprints of Papers for the International Conference on Scientific Infor- mation, National Academy of ... specifications of the component variables. The truth value associated with a given formula in a given context will be called the evaluation of the formula for that context. From the viewpoint of ... based on the automatic as- sociation of basic algorithms with dictionary entries, the automatic specification of variables, and the auto- matic evaluation of formulas. The proposed formula...

Báo cáo khoa học: "Optimal rank reduction for Linear Context-Free Rewriting Systems with Fan-Out Two" pot

... appear-ing in the left-hand side of (1) (without repeti-tions) along with some additional terminal sym-bols (with possible repetitions). For a mathematical deﬁnition of LCFRS we re-fer the ... value of the above function is kept to a min-imum. One way to achieve this is by factorizingthe productions of a LCFRS, as we now explain.2.2 FactorizationConsider a LCFRS production of the formp ... associated with aLCFRS production p, a bundle E with fan-out f and with |E| > 1 identiﬁes a set of nonterminalsC in the right-hand side of p that can be factorizedinto a new production. The nonterminals...

Báo cáo khoa học: "Data point selection for cross-language adaptation of dependency parsers" pot

... aconstituent-based parser on the training section of the Danish treebank and evaluated it on sentences of up to 40 words in the test section of the Swedishtreebank and obtained an F1-score of ... Proceedings of the 49th Annual Meeting of the Association for Computational Linguistics:shortpapers, pages 682–686,Portland, Oregon, June 19-24, 2011.c2011 Association for Computational LinguisticsData ... of abstraction. Of courseannotations differ, but nouns are likely to be depen-dents of verbs, prepositions are likely to be depen-dents of nouns, and so on. Speciﬁcally, Zeman and Resnik (2008)...

Báo cáo khoa học: "Grounded Language Modeling for Automatic Speech Recognition of Sports Video" doc

... done by processing on word pairs or triples, and performing normalization on the resulting conditional distributions. a uniform distribution (as is done with authors of documents), we select ... directly on their effect on word accu-racy or error rate, but based on their ability to sup-port video information retrieval. 4.3 Precision of Information Retrieval One of the most commonly used ... the number of word insertions, substitutions, and deletions required to transform the output tran-scription of an ASR system to a human generated gold standard transcription of the same utterance....

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