Báo cáo khoa học: Regulation of translational efficiency by different splice variants of the Disc large 1 oncosuppressor 5¢-UTR potx

... ª 2 011 FEBS Regulation of translational efficiency by different splice variants of the Disc large 1 oncosuppressor 5¢-UTR Ana L. Cavatorta 1 , Florencia Facciuto 1 , Marina Bugnon Valdano 1 , ... Farmace ´ uticas, Suipacha 5 31, 2000 Rosario, Argentina Fax: +54 3 41 4390645 Tel: +54 3 41 43506 61 E-mail: gardiol@ibr.gov.ar (Received 23 January 2 011 , re...

Ngày tải lên: 22/03/2014, 16:20

... 13 .3 13 426 0 .12 Relations 4.0 13 80288 1. 88 Delays 2.6 3633406 6.38 Path compression 2.0 9553 91 1. 31 Constraints 1. 6 15 30779 1. 62 Unification 1. 5 3 718 712 8 38.77 Dereferencing 0.5 11 67 317 77 38.44 Add ... as Figure 1 (a portion of the ERG’s for relative clauses), in which both the semantics of the subtyping links themselves (normally, subset inclu- sion) a...

Ngày tải lên: 20/02/2014, 15:21

... doi :10 .10 46/j .14 32 -10 33.2003.03 411 .x Here we report, for the first time since attempts were made in the mid -19 70s, that such an electron transfer can be effectively coupled to the oxidation of ... maintained. Detection of the products of substrate oxygenation by the adsorbed MMOH was achieved by holding the potential at )0.5 V for 30 min in the presence of...

Ngày tải lên: 17/03/2014, 09:20

... obtain- ing thermal unfolding curves of the enzymes, the CD value at 222 nm was monitored while raising the solution temperature at a rate of 1 °CÆmin )1 . By setting the ther- mocouple in the cell, ... extent as in the case of the wild-type enzyme. The mode of hydrolysis of glucosamine oligosaccha- rides [5 ,15 ,16 ], however, provides insight into the inter...

Ngày tải lên: 16/03/2014, 04:20

... effect P P P P 14 -3-3 Bax 18 4 Bax P P P P P 15 9 12 1 16 3 18 4 P P P Mcl -1 Bax P 12 1 16 3 18 4 P P Mcl -1 Bax P 18 4 Mcl -1 Bax P 18 4 Bax P 18 4 Bcl-xL Bax 13 6 11 2 15 5 P P P Bad 14 -3-3 18 4 Bad P 14 -3 -3 P P P Caspase-9 P P 364 Activation Cleavage 465397 PP P Caspase-8 15 0 Caspase-3 P Cleavage Activation P Caspase-3 Endo ... (2 011 ) 427–4 41 ª 2 010 The...

Ngày tải lên: 14/02/2014, 22:20

... 333 8000 Tel: +358 2 215 3 311 E-mail: lea.sistonen@abo.fi (Received 11 May 2 010 , revised 20 July 2 010 , accepted 11 August 2 010 ) doi :10 .11 11/ j .17 42-4658.2 010 .07828.x Regulation of gene expression ... & Sistonen L (20 01) Roles of the heat shock transcription factors in regulation of the heat shock response and beyond. FASEB J 15 , 11 18 11 31. 4 Fujimoto M...

Ngày tải lên: 18/02/2014, 04:20

... of 16 1.8, 28.2 and 13 .2 kDa, respectively. The formation of the cathepsin B ⁄ cystatin C complex was seen as a shift of the elution peak of cathepsin B (Fig. 6A). The addition of 2A2 mAb to the ... His 110 -Asp22 and Arg 116 -Asp224, which limits the access of substrates to the primed sites of the active-site cleft and thereby reduces the enzyme’s endo- pep...

Ngày tải lên: 18/02/2014, 11:20

... (75 .1) Multiplicity 12 .2 (5.5) 10 .0 (5.4) No. reflections 14 719 8 11 1034 No. unique reflections 12 085 11 1 31 Refinement statistics No. reflections (total) 12 020 10 539 No. reflections (working set) 11 438 ... main chain of the subunit, or in the interaction of subunits within the trimer that linked the conformation of residues 12 0 12 5 to the position of the...

Ngày tải lên: 18/02/2014, 16:20

... termination of the pr otein s ynthesis. These data a dd to the growing body of information supporting a preponderant role of p38 in the regulation of gene expression at the level of mRNA stability. The ... Trends Cell Biol. 11 , 4 71 477. 35. Weed, S.A., Y. & Parsons, J.T. (19 98) Translocation of cortactin to the cell periphery is mediated by the s m all GT...

Ngày tải lên: 19/02/2014, 16:20

... of 800 kDa; Tm–Tn, tropomyosin–troponin complex. (Received 11 August 2004, revised 4 October 2004, accepted 11 October 2004) Eur. J. Biochem. 2 71, 4572–45 81 (2004) Ó FEBS 2004 doi :10 .11 11/ j .14 32 -10 33.2004.04429.x have ... in the same way as T800 [64,69]. Inhibition of the ATPase activity was then explained by a slowing down of the formation of active complex in so...

Ngày tải lên: 19/02/2014, 16:20