Báo cáo Y học: DNA supercoiling in Escherichia coli is under tight and subtle homeostatic control, involving gene-expression and metabolic regulation of both topoisomerase I and DNA gyrase docx
Báo cáo Y học: DNA supercoiling in Escherichia coli is under tight and subtle homeostatic control, involving gene-expression and metabolic regulation of both topoisomerase I and DNA gyrase docx
... DNA supercoiling in Escherichia coli is under tight and subtle homeostatic control, involving gene-expression and metabolic regulation of both topoisomerase I and DNA gyrase Jacky L. Snoep1,2, ... on supercoiling: C supercoiling gyrase 1ev topoisomerase I supercoiling ekt topoisomerase I supercoilin gÀev gyrase supercoiling Àekt gyrase supercoiling ÀC supercoiling topoisomerase I 3 In this ... ekt topoisomerase I supercoiling and ekt gyrase supercoiling , re¯ectingthe s ensitivity of transcription of topoisomerase I and DNA gyrase for D NA superco iling. Certain sim pli®cations...
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Tài liệu Báo cáo khoa học: Catabolite repression in Escherichia coli – a comparison of modelling approaches docx
... complexes. EII is typically composed of EIIA, B and C domains, with the EIIA and B do-mains being part of the phosphorylation chain and theEIIC domain representing the membrane domain. Asall ... this study, we compare two models describingcatabolite repression in E. coli by discussing somerelevant issues of modelling in systems biology, modelvalidation, dynamics and control. Nishio ... carbohydrates(Fig. 1). It consists of two common cytoplasmic pro-teins, enzyme I (EI) and histidine-containing protein(HPr), as well as an array of carbohydrate-specificenzyme II (EII) complexes....
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Báo cáo Y học: Refolding of the Escherichia coli expressed extracellular domain of a7 nicotinic acetylcholine receptor Cys116 mutation diminishes aggregation and stabilizes the b structure pdf
... Refolding of the Escherichia coli expressed extracellular domain of a7 nicotinic acetylcholine receptorCys116 mutation diminishes aggregation and stabilizes the b structureVictor I. Tsetlin1, ... denaturedproteins and therefore is widely used in refolding studies[28–30]. It is assumed that the masking of hydrophobicprotein interfaces by detergent molecules results in 8thisreduction in aggregation. ... extracellulardomains; expression in Escherichia coli; Cys116 mutation;CD spectroscopy.Nicotinic acetylcholine receptors (AChRs), belonging to thefamily of ligand-gated ion channels, are divided into twomajor...
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Báo cáo khoa học: EspB from enterohaemorrhagic Escherichia coli is a natively partially folded protein pptx
... presence of some tertiary contacts involving atleast one of the tyrosines, although the intensity of each peak is not very high.To gain further insight into the conformational prop-erties of EspB, ... amino acid residues at 1–53, 128–230 and 247–287may be disordered. This is relatively consistent with theprediction of DisEMBL. If the prediction fromPONDR is correct, only the amino acid ... analysis for long disordered regions prediction in the calcineurin family. Genome Informatics 8, 110–124.60 Romero P, Obradovic Z, Kissinger CR, Villafranca JE& Dunker AK (1997) Identifying...
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Báo cáo y học: " Regional coordination in medical emergencies and major incidents; plan, execute and teach"
... presented in this study indicates that the center had achieved its primarytasks. Such regional organization with executive, planning, teaching and training responsibilitiesoffers possibilities for ... shipping and public gatherings all need to be included in the riskassessment regarding possible major incidents in thisregion. The purpose of this study was to find whether thisinstitution ... planning, teaching and training disaster medicine by giving immediate feed-back based on real incidents.BackgroundIntroductionTo be able to cope with the implications, both quantita-tive and...
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Báo cáo y học: "Special considerations in the treatment of patients with bipolar disorder and medical co-morbidities"
... urinary acidification defects [42].Patients with preexisting kidney disease are at increasedrisk for lithium toxicity and possibly the nephrotoxiceffects of lithium. Lithium is contraindicated in ... plasmaproteins, thereby increasing free-drug levels; increase in volume of distribution in patients with ascites [52].Hepatitis C virus (HCV) infection is a leading cause of cir-rhosis and liver ... electrolyte aberrations; in combination with ACE inhibitors, increased risk of arrhythmia(toxicity) Sinoatrial block; AV block/dissociation bradyarrhythmias; ventricular tachycardia/fibrillationValproate...
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Báo cáo y học: "Technical Considerations in Decompressive Craniectomy in the Treatment of Traumatic Brain Injury"
... efficacy of decompressive craniectomy in decreasing ICP and improving pr o g n o sis in patients wi th refractory in- tracranial hypertension after TBI.2-8 Presently, th e European Brain Injury ... that maintains the blood supply. Brain herniation via the craniectomy defect may lead to compression of vessels and result in ischemic necrosis of the portion of the herniated brain. Coskay et ... each incision in one row wa s adjacent to an intact dural bridge in the rows on either side. The same course was then performed, but in a direction vertical to the initial incision. This method...
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Báo cáo y học: "Pathogenic organisms in hip joint infections"
... http://www.medsci.org 237Microbiologic procedures in joint infections A differentiation of arthritis is practicable by examination of typical laboratory medicine and mi-crobiology characteristics in joint ... Abstract Infections of the hip joint are usually of bacterial etiology. Only rarely, an infectious arthritis is caused in this localization by viruses or fungi. Native joint infections of the hip ... prosthesis, therapy Infectious arthritis The infection of a joint can occur in different ways, (I) via injection or during joint operation through direct colonization, (II) by direct contact with...
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Báo cáo y học: "Genetic polymorphisms in the nucleotide excision repair pathway and lung cancer risk: A meta-analysis"
... heterozygosity and tighter linkage disequilibrium with disease-causing mutations. In ad-dition, haplotype analysis offers the advantage of not assuming that any of the genotyped polymorphisms is ... Because this polymorphism is located in the vicinity of the translation initiation codon, it may alter translation efficiency. The nearby proximal nucleo-tides to the AUG initiation codon are important ... lesions. These clinical findings are associated with cellular defects, including hypersensitivity to killing and the mutagenic effects of UV and the inability of XP cells to repair UV-induced...
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Báo cáo y học: "Prion propagation in vitro: are we there yet"
... methodology of in vitro prion propagation assays and discuss their ability in reflecting prion propaga-tion in vivo. Key words: prion disease, prion, cellular prion protein, disease-associated scrapie ... transmit disease directly to wild type mice. To obtain infectivity in wild type mice, synthetic prions were Int. J. Med. Sci. 2008, 5 352serially passaged to wild type mice only after primary ... assay to this system allowed a microplate reader to monitor the amyloid fibril formation in real time. This semi-automated assay was particularly useful in studying kinetics of amyloid fibril...
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