Báo cáo Y học: DNA supercoiling in Escherichia coli is under tight and subtle homeostatic control, involving gene-expression and metabolic regulation of both topoisomerase I and DNA gyrase docx

... DNA supercoiling in Escherichia coli is under tight and subtle homeostatic control, involving gene-expression and metabolic regulation of both topoisomerase I and DNA gyrase Jacky L. Snoep 1,2 , ... on supercoiling: C supercoiling gyrase  1 e v topoisomerase I supercoiling e kt topoisomerase I supercoilin g Àe v gyrase super...

Ngày tải lên: 18/03/2014, 01:20

... complexes. EII is typically composed of EIIA, B and C domains, with the EIIA and B do- mains being part of the phosphorylation chain and the EIIC domain representing the membrane domain. As all ... this study, we compare two models describing catabolite repression in E. coli by discussing some relevant issues of modelling in systems biology, model validation, dynamics and...

Ngày tải lên: 18/02/2014, 13:20

... Refolding of the Escherichia coli expressed extracellular domain of a7 nicotinic acetylcholine receptor Cys116 mutation diminishes aggregation and stabilizes the b structure Victor I. Tsetlin 1 , ... denatured proteins and therefore is widely used in refolding studies [28–30]. It is assumed that the masking of hydrophobic protein interfaces by detergent molecules results...

Ngày tải lên: 31/03/2014, 23:20

... presence of some tertiary contacts involving at least one of the tyrosines, although the intensity of each peak is not very high. To gain further insight into the conformational prop- erties of EspB, ... amino acid residues at 1–53, 128–230 and 247–287 may be disordered. This is relatively consistent with the prediction of DisEMBL. If the prediction from PONDR is correct,...

Ngày tải lên: 16/03/2014, 18:20

... presented in this study indicates that the center had achieved its primary tasks. Such regional organization with executive, planning, teaching and training responsibilities offers possibilities for ... shipping and public gatherings all need to be included in the risk assessment regarding possible major incidents in this region. The purpose of this study was to find whether this...

Ngày tải lên: 25/10/2012, 09:56

... urinary acidification defects [42]. Patients with preexisting kidney disease are at increased risk for lithium toxicity and possibly the nephrotoxic effects of lithium. Lithium is contraindicated in ... plasma proteins, thereby increasing free-drug levels; increase in volume of distribution in patients with ascites [52]. Hepatitis C virus (HCV) infection is a leading cause of...

Ngày tải lên: 25/10/2012, 10:51

... efficacy of decompressive craniectomy in decreasing ICP and improving pr o g n o sis in patients wi th refractory in- tracranial hypertension after TBI. 2-8 Presently, th e European Brain Injury ... that maintains the blood supply. Brain herniation via the craniectomy defect may lead to compression of vessels and result in ischemic necrosis of the portion of the her...

Ngày tải lên: 25/10/2012, 11:40

... http://www.medsci.org 237 Microbiologic procedures in joint infections A differentiation of arthritis is practicable by examination of typical laboratory medicine and mi- crobiology characteristics in joint ... Abstract Infections of the hip joint are usually of bacterial etiology. Only rarely, an infectious arthritis is caused in this localization by viruses or fung...

Ngày tải lên: 26/10/2012, 09:57

... heterozygosity and tighter linkage disequilibrium with disease-causing mutations. In ad- dition, haplotype analysis offers the advantage of not assuming that any of the genotyped polymorphisms is ... Because this polymorphism is located in the vicinity of the translation initiation codon, it may alter translation efficiency. The nearby proximal nucleo- tides to the AUG ini...

Ngày tải lên: 31/10/2012, 14:59

... methodology of in vitro prion propagation assays and discuss their ability in reflecting prion propaga- tion in vivo. Key words: prion disease, prion, cellular prion protein, disease-associated scrapie ... transmit disease directly to wild type mice. To obtain infectivity in wild type mice, synthetic prions were Int. J. Med. Sci. 2008, 5 352 serially passaged to wild type m...

Ngày tải lên: 03/11/2012, 11:52