Báo cáo Y học: Synthesis of phosphoenol pyruvate (PEP) analogues and evaluation as inhibitors of PEP-utilizing enzymes pot
Báo cáo Y học: Synthesis of phosphoenol pyruvate (PEP) analogues and evaluation as inhibitors of PEP-utilizing enzymes pot
... as inhibitors of the reaction betweenADPandPEPcatalysedbypyruvatekinase. Pyruvic acid is one of the products of this reaction. Therefore, activity was measured by coupling the formation of pyruvate ... J. Biochem. 269) Ó FEBS 2002 Synthesis of phospho enol pyruvate (PEP) analogues and evaluation as inhibitors of PEP-utilizing enzymes Luis Fernando Garcı...
Ngày tải lên: 18/03/2014, 01:20
Báo cáo Y học: High affinity binding between laminin and laminin binding protein of Leishmania is stimulated by zinc and may involve laminin zinc-finger like sequences doc
... High affinity binding between laminin and laminin binding protein of Leishmania is stimulated by zinc and may involve laminin zinc-finger like sequences Keya Bandyopadhyay, Sudipan Karmakar, ... Ghosh and Pijush K. Das Molecular Cell Biology Laboratory, Indian Institute of Chemical Biology, Jadavpur, Calcutta, India In the course of trying to understand the pathogenesis of leishma...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo Y học: Interaction between p21-activated protein kinase and Rac during differentiation of HL-60 human promyelocytic leukemia cell induced by all-trans-retinoic acid pdf
... autophos- phorylation and kinase activity of PAK were stimulated by binding to activated Rac/Cdc42, which thereby directly modulates the enzyme activity [7–11]. However, Rho did not show binding activity ... 95% neutrophil granulocytes. Measurements of reactive oxygen species Superoxide generating activity was spectrophotometrically assayed by monitoring SOD-inhibitable ferricytochrome...
Ngày tải lên: 31/03/2014, 15:20
Báo cáo Y học: Conformationally constrained human calcitonin (hCt) analogues reveal a critical role of sequence 17–21 for the oligomerization state and bioactivity of hCt ppt
... and in vivo hypocalcemic potencies were assessed. The novel analogues include cyclo17,21-[Asp17, D -Phe19, Lys21]hCt (2), cyclo17,21-[Asp17,Aib18,Lys21]hCt (3), cyclo17,21-[Asp17, D -Lys18,Lys21]hCt ... ffect of the inversement of ch irality of Phe19 on in vivo bioactivity of 1. In contrast, 6 had the same potency and maximum effe ct as hCt which suggested that inverse- ment...
Ngày tải lên: 31/03/2014, 21:21
Báo cáo Y học: Synthesis and turn-over of the replicative Cdc6 protein during the HeLa cell cycle potx
... yeast cell cycle. They rapidly decrease w ith the entry of yeast cells into S phase and increase again during t he following G1 phase with the synthesis of new Cdc6p. In contrast, the rapid S-phase-related ... (0–2 h after thymidine-block) and in the middle of S phase (4–6 h), as well as at the e nd of mitosis and during the early G1 phase (12–14 h) of the next cycle (Fi...
Ngày tải lên: 17/03/2014, 23:20
Báo cáo Y học: Synthesis, characterization and application of two nucleoside triphosphate analogues, GTPcNH2 and GTPcF pdf
... investigated. The rate of hydrolysis of GTPcNH 2 bound to Ras protein lay between the rates found for Ras-bound GTPcS and GppNHp, while Ras-catalysed hydrolysis of GTPcF was almost as fast as for GTP. The ... function, structure and mechanism, often demands use of nonhy- drolyzable or slowly hydrolyzable nucleotide analogues. These modifications become necessary when stabiliz...
Ngày tải lên: 18/03/2014, 01:20
Báo cáo Y học: Synthesis, conformational analysis and biological activity of cyclic analogs of the octadecaneuropeptide ODN Design of a potent endozepine antagonist pot
... those previously observed with ODN and OP [12]. However, we found that the potency of cyclo 128 OP was increased by a factor of three and its efficacy by a factor of 1.4 compared to its linear counterpart ... preloaded 4-hydroxymethyl- phenoxymethyl-copolystyrene-1%-divinylbenzene resin [Fmoc-Lys(Boc)-HMP], O-benzotriazol-1-yl-N,N,N 0 ,N 0 - tetramethyluronium hexafluorophosphate (HBT...
Ngày tải lên: 24/03/2014, 04:21
Báo cáo y học: "Electronic patient record use during ward rounds: a qualitative study of interaction between medical staff"
... validation of hypotheses generated during video analysis about the interac- tion. Quantitative measures were not used as it was unlikely they would provide external validity in this situation of complex social ... months after deployment of the system, and the effects of the introduction of the EPR on group interaction were discussed. Patient privacy was ensured at all times by...
Ngày tải lên: 25/10/2012, 10:31
Báo cáo y học: "980 nm diode lasers in oral and facial practice: current state of the science and art"
... suggestions of scientific literature on the advantages of the compactness, reliability, ease of use and affordability of the 980 nm Diode Lasers, we evaluated the efficacy and safety of one such Laser ... Immunology and Infectious Diseases, Unit of Dermatology, University of Bari, Italy Correspondence to: Dr. Andrea BALLINI, PhD., Department of Dental Sciences and...
Ngày tải lên: 26/10/2012, 09:48
Báo cáo y học: " Laugh Yourself into a Healthier Person: A Cross Cultural Analysis of the Effects of Varying Levels of Laughter on Health"
... lifestyle. The total score was thirty-seven. Lifestyle Q1 to Lifestyle Q3 were equally weighted and represented 81% of the total value of the questions, whereas, Lifestyle Q4 and Lifestyle Q5 ... appropriately describe laughter-associated-asthma. The World Health Organization defined health as a “state of physical, mental and social well-being and not merely the absence...
Ngày tải lên: 26/10/2012, 09:57